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Table of Contents
Why is my testosterone cypionate crystallizing?
Testosterone Cypionate Crystalization
Because of Testosterone cypionate’s high concentration, it is susceptible to something called crystallization when it is left outside of the recommended Testosterone storage temperature range (68° – 77°F).
Can you heat up testosterone?
Take a hot shower or bath before taking your shot, to warm your muscles. Put the unopened vial in warm water or under your armpit for a minute to warm up the oil, or rub the unopened vial between your hands.
Should I store testosterone in the fridge?
What should I know about storage and disposal of this medication? Keep testosterone enanthate injection (Xyosted) in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom). Do not refrigerate or freeze.
How long can you store testosterone?
36 months. Store at 20°C – 25°C (see USP Controlled Room Temperature) and protect from light.
How long does an open vial of testosterone last?
If a multi-dose has been opened or accessed (e.g., needle-punctured) the vial should be dated and discarded within 28 days unless the manufacturer specifies a different (shorter or longer) date for that opened vial.
Testosterone Injection: MedlinePlus Drug Information
Medication vials should be discarded whenever sterility is compromised or cannot be confirmed. In addition, the United States Pharmacopeia (USP) General Chapter 797 [16] recommends the following for multi-dose vials of sterile drugs:
If a multiple dose has been opened or accessed (eg, needle puncture), the vial should be dated within 28 days and discarded, unless the manufacturer specifies a different (shorter or longer) date for that opened vial.
If a multidose vial has not been opened or accessed (eg, needle puncture), it should be discarded according to the manufacturer’s expiration date.
The manufacturer’s expiration date refers to the date after which an unopened multidose vial should no longer be used. The best before date refers to the date after which an opened multidose vial should no longer be used. The best before date should never exceed the manufacturer’s original expiration date.
For vaccine storage and handling information, refer to the CDC Vaccine Storage and Handling Toolkit or the manufacturer’s recommendations for specific vaccines.
What temperature should you store testosterone?
Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Protect from light.
Testosterone Injection: MedlinePlus Drug Information
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Information selected for pacientes and cuidadores que se encuentra available in Español.
Is it better to inject testosterone once or twice a week?
Twice per week is preferred for the balance of testosterone delivery. What’s the best place to inject testosterone? This is really about personal preference; where it’s the least painful and easiest for you to inject.
Testosterone Injection: MedlinePlus Drug Information
Talk to your doctor first
Any doctor can show you how to give yourself an injection; If you need help, email us and we’ll arrange a live tutorial. Both can help you troubleshoot problems or point out common mistakes, and as telemedicine becomes more prevalent, video chatting with a doctor to observe your first shot is becoming more common. This can help calm you down through the tremendous mental jitters surrounding your first shot.
And after the first shot, it really gets easier. Almost all of my patients end the first self-injection with the words: “That’s it?! That was nothing.”
Prepare your mind and gear
Let’s go through some common questions you may have to clear up some common misconceptions about self-injection.
First, is self-injection safe?
Self-injection, done properly – that is, with a prescribed substance, under the direction of a doctor – is completely safe. black-market needles, home-sourced substances, and using one’s own needles; These are things that make self-injection unsafe. As long as your course of treatment is guided by a doctor, you’re good.
Is it difficult to inject yourself?
It’s not difficult. The first shot will be the hardest, but the rest will go smoothly. The biggest fear here is the pain associated with the needle and a phobia of needles themselves. If I have a patient who struggles with self-injections, my advice is:
Numb the injection site. You can do this by putting ice on it for a minute or two before injecting. Or you can use an over-the-counter numbing medication like Aspercreme with lidocaine. If you don’t feel the needle sticking in, that helps a lot.
Concentrate on breathing. It’s common to hyperventilate because of anxiety. Focus on taking measured, deep breaths to stay calm.
Stretch the skin at the injection site. Just before positioning the needle, spread the skin as tightly as possible with your thumb and forefinger. It helps distract your brain by refocusing on the tactile sensation, but it also allows the needle to poke in more easily.
Try a tool like Buzzy. We use Buzzy in the emergency room for anyone who has a needle phobia. It’s a device with an attached freezer bag and a vibrating motor that you position directly over the injection site. Your body feels both the cold and a vibration; The cool sensation helps block pain while the vibration keeps the brain busy so it can’t focus on fear of the shot.
Try an auto-injector. You simply load and position the syringe and push a button. The auto-injector shoots the needle in and you push the plunger. These can help a lot.
Look away at the last second. If you position the needle and turn your head away as you push it in, then push the plunger can help. Many people do not like to watch the needle penetrate their skin.
How do you overcome the fear of injections?
It’s really about surviving the first shot. Before every patient who has to inject himself tries to do it alone, we do a test run with me in the room. This helps them see how easy this is and that they can definitely do it on their own.
Just new needles
Never reuse needles. Reusing needles is problematic because they are unsanitary, but also because the needle dulls immediately after the first use, meaning the next use will be more painful. Always keep a fresh supply of new needles at home and use one for each injection.
understand syringes
A needle is part of a syringe. Let’s quickly talk about the other parts. The tip is the part of the syringe where the needle attaches. The barrel is the portion of the tube that is open at one end and narrows into the hollow tip at the other end. There are lines on the barrel to help you see the volume of the solution inside. The piston is the rod that sits in the cylinder and works like a piston; You can pull or push to get solutions in and out of the barrel.
Know your needle and gauge sizes
You can connect multiple needles to one syringe depending on the action required. Needle diameter is measured by numbers that indicate the bore of a needle lumen (a fancy word for the hole at the tip of the needle). The higher the reading, the smaller or thinner the hole; The lower the reading, the larger or thicker the hole. Stronger needles can reduce pain when injecting, but larger needles are needed to inject larger amounts of oil-based substances (like testosterone) into the muscle.
The last thing you need to know about needles is the length of the needle itself. This number is listed after the gauge number. For example, a 25G ½ indicates it is a 25 gauge needle that is half an inch long.
The injection site determines your needle
The injection site will help you determine needle size, but your weight may also play a role; Slightly taller people may need a slightly larger needle because the needle can penetrate more tissue.
At Hone, we recommend three needle sizes, one for injections under the skin – subcutaneous (or SubQ) – and two for injections going into the muscle – intramuscular (or IM). More about these two types of injections the same, but the hypodermic needle is 27-30 gauge and either 1/2 inch to ⅝ inch long.
For intramuscular injections, we will send two needles: a 20 gauge to draw up the drug and a 23 gauge for the injection itself (some people may be able to use these for a subcutaneous injection after some experience). Intramuscular needles are longer, between an inch and an inch and a half, because they have to penetrate the muscle.
The rest of your gear
It is important to have everything prepared and ready before you start self-injecting. You don’t want to be in the thick of it and realize you need something practical. You should have the following things within reach.
Your testosterone or medication vial
needles and syringes
alcohol wipes. You should sterilize and disinfect the rubber cap on the medicine vial and your injection site
Gauze or cotton ball, then immediately apply gentle pressure to the injection site for a few seconds
Band-aid if there is blood (this is more common with intramuscular injections)
A sharps container. This is a puncture resistant container for safe disposal of the needle
Soap so you can wash your hands thoroughly
Clean everything
First, you should wash your hands with soap for at least 20 seconds. Next, clean the top of your medication vial with an alcohol swab and allow it to dry completely (you don’t want to force any residual alcohol into the testosterone or medication). Next, you should scrub your injection site with a fresh alcohol swab and allow that to dry completely as well. Finally, if you need an injection device like Buzzy or ice, or an anesthetic, have that handy.
What are you injecting?
When you are on testosterone replacement therapy (TRT), you inject testosterone. Again, injecting testosterone is perfectly safe provided you are working under the guidance of a doctor. There are several ways to get testosterone into your body, but the advantages of injecting testosterone are that injections are highly effective and the dosage is consistent, as studies have shown. Testosterone in the bloodstream is eliminated quickly, so injections slowly release the hormone into the bloodstream over an extended period of time.
In addition, studies also show greater muscle strengthening with injections, confirming that testosterone injections are the best method for testosterone replacement therapy.
Frequently Asked Questions About Testosterone Injection
What is the best time of day to inject testosterone?
Traditionally it is the morning. It is not scientifically necessary to inject testosterone in the morning, even though our testosterone is highest in the morning. Rather, the reason for the morning boost is to create a routine to ensure you don’t miss doses.
However, there is no difference in the time of day you inject; I haven’t seen any study that suggests that effectiveness changes between morning and afternoon or evening. Whatever time you choose, stick to that time. Consistency is key to building a routine.
Is it better to inject testosterone once or twice a week?
The answer here varies depending on your doctor’s preference, but also your dosage. As a rule, once or twice a week is the norm. Some guys don’t want to self-inject twice a week, so they want to get the whole week’s dose all at once.
For example, if your course of treatment calls for a 200mg dose, with one shot of every 200mg, your testosterone levels would peak about four days later and then drop off. If you injected 100mg at the beginning of the week and another 100mg towards the end of the week, your peak won’t be as high and your trough won’t be as low. Twice a week is preferred for the remainder of testosterone delivery.
What is the best place to inject testosterone?
This is really a matter of personal preference; where it is least painful for you and easiest to inject. If you have help in the form of a loved one or friend, you can do an intramuscular injection in the upper gluteus maximus or deltoid. If you are injecting yourself, you can do a subcutaneous injection and use the abdomen or upper outer thigh (never the inner thigh; there are too many veins to hit).
What time of day should I inject testosterone?
In young men, the concentrations are highest in the morning. Older men tend to have similar, but blunted, patterns. Clinicians should draw serum testosterone levels between 8:00 am and 11:00 am.
Testosterone Injection: MedlinePlus Drug Information
The primary indication for prescription testosterone is replacement therapy for deficiency (i.e., androgen deficiency syndrome or hypogonadism). Although a variety of testosterone formulations are available today, public concern is considerable. Pharmacists need to know 10 important points about Testosterone Replacement Therapy (TRT) to allay concerns and ensure patient safety.
1. The androgenic effects of testosterone begin in the perinatal period when the sex organs are developing. They continue through puberty and stimulate secondary sex characteristics such as deepening of the voice, growth of facial hair and development of armpit hair. The anabolic effects of testosterone increase muscle mass, strength, bone density, and bone maturation throughout life.3,4
2. The FDA has approved TRT for classic androgen deficiency caused by pathological conditions (eg, Klinefelter syndrome, orchiectomy, chemotherapy). Many prescribing physicians also use testosterone for age-related testosterone decline, known as late-onset hypogonadism. This is an off-label use.3
The 2010 Endocrine Society Clinical Practice guidelines did not address some population groups, but the results of later studies indicate that men with metabolic syndrome or frailty may benefit from TRT due to improvements in biometrics, insulin sensitivity, muscle strength and bone health.4
3. Endocrine Society guidelines indicate that in order to diagnose testosterone deficiency in a patient, the patient must have:
Why do I feel so tired after a testosterone shot?
Fatigue is a common effect of low testosterone. You might feel like you just don’t have the energy that you’re used to. Or you might be incredibly tired. These symptoms can add up to chronic low energy, and mental and physical fatigue.
Testosterone Injection: MedlinePlus Drug Information
We go up and down the details of TRT and answer the big questions that many other providers won’t answer. Here at Focal Point Vitality, we are all about educating our guests on the road to success with sound information, science-based studies and the like.
And today we cover one of the most frequently asked questions about TRT: how long does it take for testosterone replacement therapy to work?
How long does it take for testosterone replacement therapy to start working?
Both scientific studies and our clinical experience have shown that testosterone therapy provides a balance of short- and long-term effects. While it can take up to several months to fully resolve all of your low-T symptoms, you may start to see improvements much sooner.
Many men begin to feel the benefits of TRT within a few weeks of starting treatment and are fully achieving their wellness goals within four to six months.
At Focal Point we work hard to optimize your testosterone to ensure you get the maximum benefit from therapy. This is where Focal Point has become a leader in testosterone therapy. After your initial consultation and treatment plan, we will schedule a blood draw in 6-8 weeks to see how the body is responding to the therapy. We look for key indicators like free testosterone, DHEA, vitamin D and SHBG to understand how the body uses testosterone. This is where the “magic” happens and our patients begin to feel the full benefits of testosterone therapy.
Once our guests are optimized with testosterone, we have the option to introduce peptide therapy. This is like supercharging therapy as we start working with other hormones like growth hormone using CJC/IPAMORELIN and others to enhance testosterone therapy.
Things that can happen to your body after you start taking testosterone
When your body runs out of testosterone, it’s akin to trying to drive a sports car with an empty tank of gas (and more than a few mechanical problems). But when you start replenishing low T levels, your body can run like a finely tuned machine again.
Testosterone affects everything from your sex drive and muscle mass to your focus and mood. So when things get out of hand, you’ll really notice.
Symptoms of low testosterone range from physical to mental and can include:
The feeling of having zero energy
mental clarity
Erectile dysfunction/less interest in sex
Bad mood or down
Extra fat builds up around your abdomen and other areas
But once you start taking testosterone, you can expect these symptoms to subside. Remember, the best way to manage low T is with a comprehensive plan of attack – in other words, combining TRT, nutrition and fitness strategies, stress management, and other tactics will maximize your results.
Short-term effects of testosterone replacement therapy
Most people want to see signs that TRT is working, and they want to see them fast. And while it can take several months for the full effects of testosterone treatment to kick in, there are some short-term benefits that are more than worth the wait.
Your energy levels will get a jump start. Fatigue is a common consequence of low testosterone. You may feel like you just don’t have the energy you’re used to. Or you could be incredibly tired. These symptoms can add up to chronic lack of energy and mental and physical exhaustion. Studies have shown that men’s energy improves after they start TRT. Your mood changes to a positive one. Depression is common in men with low testosterone, but TRT can provide a big boost. You can usually expect to start feeling happier and more positive in three to four weeks, with a noticeable decrease in periods of depression within about three to six weeks. Diabetes takes a double whammy. If you are diabetic or pre-diabetic, TRT could produce an almost immediate improvement in your insulin sensitivity. Measurable progress can be seen in just a few days and complete glycemic control can be yours for the long term.
Long-term effects of testosterone replacement therapy
Once you get past the thrill of the initial effects of TRT, don’t give up – because there’s great reward to be had if you keep up with the treatment.
Your sex life will continue to heat up. You’ll probably be feeling “in the mood” within a few weeks of starting TRT, but your bedroom performance is only getting better. Over the next several months, you may experience improved erections. And of course, a side effect of this is that you feel more confident and enthusiastic about sex. It will be easier to get your body back in shape. After a few months, you should see a visible difference in your body composition. Less fat and more muscle is a natural part of balancing Low-T, and even your bones will get stronger. Understandably, men want to make sure they are not exposed to any serious health issues or negative side effects of TRT in the long run. But studies have shown us that TRT is an extremely effective and safe option for many men. In 2015, the American Heart Association held scientific sessions to highlight that healthy men who underwent TRT did not have an increased risk of heart attack, stroke, or death. Another 2015 study (with tens of thousands of patients enrolled) found no association between TRT and blood clots. These two studies — and others — are referenced in Harvard Health’s latest TR findings. Key Things to Look for in a TRT Provider As you prepare to launch TRT, choose your provider wisely. Partnering with the right one makes all the difference in your treatment experience and results, both in terms of how quickly you progress and how big your improvements are. You want a TRT provider who is an expert in age management and hormonal health so they can create you a personalized plan with the most effective strategies. TRT isn’t a one-size-fits-all treatment, so avoid any place that sets you up with a general plan or doesn’t assess your specific symptoms and medical condition. At Focal Point Vitality, we take a 360-degree approach to men’s wellbeing. This means that from day one we focus on providing training, support and the best options for your needs. You won’t be viewed as a potential sale here – our goal is to build rock-solid relationships with our guests and ensure we move you on the path to your best life. It’s like having a good friend who happens to be an industry-leading expert in TRT, hormonal health and age management… You can have complete peace of mind knowing you are in good hands. Start reaping the rewards of TRT now with the help of Focal Point Vitality. What if within the next few weeks – or even the next few days – you could see serious improvements in your quality of life? With TRT this is absolutely possible; and all you have to do is take that first step. Focal Point Vitality makes it easy for you with nationwide available TRT and services through our partner labs to get you access to treatments now. Effective, life-changing, and surprisingly affordable, testosterone therapy can put you back on the path to being your best self. Why wait any longer? Get in touch with our team and arrange a non-binding consultation today! Featured Image: BLACKDAY/Shutterstock
Do you feel testosterone shots right away?
For men who are prescribed testosterone replacement therapy, it usually takes three to six months to work, Farooq says. “Some men may see improvement sooner, but for most men it’s a gradual process,” Farooq says. “Don’t expect a miracle overnight.”
Testosterone Injection: MedlinePlus Drug Information
There is no quick fix, but your first step is to contact your doctor, who may recommend treatment for low testosterone. Aside from causing a drop in your sex drive and energy levels, low testosterone levels can increase your risk of heart disease, depression, type 2 diabetes and osteoporosis.
Treating and Dealing with Low Testosterone: Getting Started
If your low testosterone levels are being caused by an underlying health condition, such as obesity, type 2 diabetes, or sleep apnea, treating that condition can help improve testosterone deficiency, says Ahmer Farooq, DO, an assistant professor of urology at Loyola University Medical Center in Maywood, Ill.
Many doctors also recommend an overall healthy lifestyle as a first approach. But even if you are prescribed testosterone treatment, diet, exercise, managing stress and other healthy habits are important to keep symptoms of low testosterone at bay as well.
“Eat foods low in saturated fat and get regular exercise,” says Dr. Farooq.
A 2013 study published in the Journal of Sexual Medicine found that men who engaged in moderate-intensity aerobic exercise for more than 3½ hours per week had greater improvements in testosterone levels, sexual function, and losing weight and abdominal fat than did Men who did less than 3.5 hours 2½ hours of physical activity per week.
Treatment options for low testosterone levels
Treatment for low testosterone may include hormone replacement therapy. “Essentially, the body is getting the testosterone it lost,” says Farooq.
For some men, testosterone replacement therapy can help improve sex drive, relieve symptoms of depression, and increase energy levels. Treatment can also increase muscle mass and bone density.
Testosterone replacement therapy comes in a variety of forms, says Dr. Farooq. The most common form is a topical gel. About 70 percent of men on testosterone replacement therapy use these gels on a daily basis.
“Gels are used in places where men are less likely to come into contact with women or children, such as the inner thigh, shoulder or armpit,” says Farooq. And the gel should only be applied to areas of the body that are covered by clothing to avoid contact with others.
About 17 percent of men being treated for low testosterone receive testosterone injections every 7 to 22 days. Testosterone levels peak two to three days after injection and then slowly decline until the next dose of the hormone is administered.
There are also testosterone patches that men can use. These patches can be applied to areas of the body such as the back, stomach, upper arm or thigh. About 10 percent of men with low testosterone use the patches. The skin absorbs the testosterone, which is slowly released into the bloodstream.
An uncommon option, used by no more than 3 percent of men being treated for low testosterone, is implanted testosterone pellets. Over the course of three to four months, the pellets slowly release testosterone into the body. The process must then be repeated.
Oral medications are rarely used to treat low testosterone because these medications have potentially harmful side effects on the liver.
When will low testosterone treatment start working?
Men who are prescribed testosterone replacement therapy typically take three to six months to take effect, Farooq says.
“Some men may see improvement sooner, but for most men it’s a gradual process,” says Farooq. “Don’t expect a miracle overnight.”
However, a 2011 study published in the European Journal of Endocrinology suggested that the effects of testosterone replacement therapy on male libido and symptoms of depression may begin after three weeks.
Treating low testosterone is an ongoing process and is usually continued over the long term. As with many other chronic conditions, if you stop therapy, the problem will return – your testosterone levels will fall back below normal.
Possible risks of low testosterone treatment
The number of men using testosterone replacement therapy in the United States has increased dramatically in recent years. Several short-term studies have shown that it is an effective treatment in appropriately selected individuals, but the long-term effects remain unclear.
Like any other drug, testosterone replacement therapy carries certain risks. Although the research has shown mixed results, it could potentially stimulate the growth of existing prostate cancer. Men diagnosed with breast or prostate cancer are not candidates for testosterone replacement therapy, Farooq says.
Testosterone replacement could also contribute to sleep apnea. Farooq says men should be screened for sleep apnea before receiving treatment for low testosterone. Treating low testosterone can also limit sperm production, cause your body to make too many red blood cells, or cause acne or breast enlargement.
“It’s important to look at a man’s low testosterone levels and weigh the risks and benefits of treatment,” says Farooq. He also says that if you’re concerned about discussing your concerns or symptoms with your doctor, it can be helpful to bring your spouse or partner with you to checkups.
When to schedule follow-up appointments with your doctor
“During the first year of treatment for low testosterone, men are usually screened every three months to check their blood and testosterone levels,” says Farooq. Tests you can expect include the prostate cancer screening test for prostate-specific antigen (PSA) and blood tests to measure lipids, liver function, and red blood cell counts.
“If you’re healthy after a year, follow-up visits can be every six months,” says Farooq. “It’s important to make sure you don’t develop any of the possible side effects of the treatment.”
How much testosterone should I inject?
Your doctor will decide a dosage based on your needs. In general, the dosage is 50–400 mg injected into your muscle every 2–4 weeks. Dosage increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
Testosterone Injection: MedlinePlus Drug Information
Important Warnings Cardiac Effects Warning: No long-term studies have been conducted to know if testosterone replacement therapy has any adverse effects on heart health in men. However, short-term studies have shown that this drug may increase your risk of heart attack, stroke, or death.
No long-term studies have been conducted to know if testosterone replacement therapy has any adverse effects on heart health in men. However, short-term studies have shown that this drug may increase your risk of heart attack, stroke, or death. Liver problems warning: Long-term use of high doses of this drug may increase the risk of liver problems. These problems include liver cancer and hepatitis. These are serious medical conditions that can be life-threatening.
Using high doses of this medicine for a long time can increase the risk of liver problems. These problems include liver cancer and hepatitis. These are serious medical conditions that can be life-threatening. Blood clots warning: This drug may increase your risk of developing blood clots in your lungs or the deep veins of your legs.
This drug can increase your risk of developing blood clots in your lungs or the deep veins of your legs. Abuse Warning: Testosterone can be abused. There is an increased risk if you take the drug in higher doses than your doctor has prescribed for you or if you use it in conjunction with other anabolic steroids. Testosterone abuse can lead to serious health problems. These problems include heart attack, heart failure, depression and psychosis. Your doctor can tell you more about the risks of testosterone abuse.
What is Testosterone Cypionate? Testosterone cypionate is a prescription drug. It is given as an injectable solution into the muscle. Testosterone cypionate is a self-injectable drug. You can give yourself this medication at home after your doctor has shown you how. Testosterone cypionate is available as the brand name drug Depo-Testosterone. It is also available as a generic. Generic drugs usually cost less than the branded version. In some cases, they may not be available in every strength or form as a branded drug. Testosterone cypionate is a controlled substance. This means that it is regulated by the government. Why it is used Testosterone cypionate is used to treat symptoms of hypogonadism in men. In this condition, men do not produce enough of the sex hormone testosterone. Low testosterone levels in men can lead to mood swings, poor concentration, erectile dysfunction (difficulty getting or maintaining an erection), and low sex drive. It can also cause decreased growth of the penis and testicles, gynecomastia (breast growth), loss of body hair and muscle mass, anemia, and osteoporosis. There are two types of hypogonadism: primary and hypogonadotropic. This drug can be used to treat both. Primary hypogonadism occurs when the testicles cannot produce enough testosterone.
occurs when the testicles cannot produce enough testosterone. Hypogonadotropic hypogonadism occurs when parts of the brain (hypothalamus or pituitary gland) that tell the testicles to produce testosterone are damaged. How it works Testosterone Cypionate belongs to a class of drugs called androgens. A drug class is a group of drugs that work in a similar way. These drugs are often used to treat similar conditions. Testosterone cypionate works to treat hypogonadism in men by replacing the testosterone that your body cannot make.
Testosterone Cypionate Side Effects Testosterone Cypionate Injectable Solution does not cause drowsiness but may cause other side effects. More Common Side Effects Some of the more common side effects of testosterone cypionate include: Acne
Pain and swelling at the injection site
hair growth
Gynecomastia (breast enlargement)
more frequent erections
Erections that last longer than normal
mood swings
headache
Decrease in sperm count when the drug is used in high doses. If these effects are mild, they may go away within a few days or a few weeks. If they get more severe or don’t go away, talk to your doctor or pharmacist. Serious side effects Call your doctor at once if you have any serious side effects. Call 911 if your symptoms feel life-threatening or if you think you have a medical emergency. Serious side effects and their symptoms may include: Heart attack. Symptoms may include the following: chest pain shortness of breath upper body discomfort
Stroke. Symptoms may include: weakness in one part or side of your body slurred speech
Enlargement of your prostate. Symptoms may include: frequent or urgent need to urinate nocturia (needing to urinate more often at night) difficulty urinating weak stream of urine, or a stream that stops and starts to dribbling at the end of urination straining to urinate not being able to empty your bladder completely
prostate cancer. Your doctor should screen for prostate cancer or prostate problems before and during treatment with this drug, especially if you are 65 years of age or older.
liver problems. Symptoms may include: feeling sick (nausea) vomiting abdominal pain and swelling swelling in your legs and ankles bruising more easily than normal pale stools unusual or unexplained tiredness loss of appetite dark-colored urine yellowing of the skin or whites of the eyes
Deep vein thrombosis (blood clots in the deep veins of the legs). Symptoms may include: swelling of your leg leg pain
pulmonary embolism (blood clots in the lungs). Symptoms may include: shortness of breath chest pain or discomfort, which gets worse if you take a deep breath or cough feeling lightheaded or dizzy or fainting fast heart rate coughing up blood
Polycythemia (increase in the number of your red blood cells). Symptoms may include the following: flushing headache confusion stroke blood clots tiredness decrease in mental alertness
Disclaimer: Our goal is to provide you with the most relevant and up-to-date information. However, because medicines affect everyone differently, we cannot guarantee that this information includes all possible side effects. This information does not replace medical advice. Always discuss possible side effects with a doctor who knows your medical history.
Testosterone Cypionate May Interact with Other Drugs Testosterone Cypionate Injectable Solution may interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To avoid interactions, your doctor should carefully manage all your medications. Be sure to tell your doctor about all medications, vitamins, or herbs you are taking. To find out how this medication might interact with something else you’re taking, talk to your doctor or pharmacist. Examples of drugs that can cause testosterone cypionate interactions are listed below. Interactions that increase the risk of side effects Taking testosterone cypionate with certain medications increases the risk of side effects from those medications. Examples of these drugs include: insulin and oral diabetes drugs such as nateglinide, pioglitazone, repaglinide, rosiglitazone, metformin, glimepiride, glipizide, sitagliptin, saxagliptin, linagliptin, exenatide, and liraglutide. Taking these medicines at the same time can lead to a significant reduction in your blood sugar levels. Your doctor may lower the dose of your diabetes medication. You may need to monitor your blood sugar levels closely while taking these medicines together.
Taking these medicines at the same time can lead to a significant reduction in your blood sugar levels. Your doctor may lower the dose of your diabetes medication. You may need to monitor your blood sugar levels closely while taking these medicines together. Oral blood thinners such as warfarin. Taking these medicines at the same time can increase the risk of bleeding. Your doctor will monitor you closely if you take these medicines together.
Taking these medicines at the same time can increase the risk of bleeding. Your doctor will monitor you closely if you take these medicines together. Corticosteroids and adrenocorticotropic hormone. Taking these drugs with testosterone cypionate puts you at greater risk of edema (fluid retention). Your doctor should monitor you closely for fluid buildup when you take these medicines together, especially if you have heart or liver problems. Disclaimer: Our goal is to provide you with the most relevant and up-to-date information. However, because medications affect everyone differently, we cannot guarantee that this information includes all possible interactions. This information does not replace medical advice. Always talk to your doctor about possible interactions with all prescription drugs, vitamins, herbs and dietary supplements, and over-the-counter medicines you are taking.
Testosterone Cypionate Warnings This drug comes with several warnings. Allergy warning Testosterone cypionate can cause a severe allergic reaction. Adverse symptoms may include the following: Difficulty breathing
Swelling of your throat or tongue If you develop these symptoms, call 911 or go to the nearest emergency room. Do not take this drug again if you have ever had an allergic reaction to it. Re-administration could be fatal (cause death). Warnings for people with certain health conditions For people with liver problems: This drug can cause liver damage. This can lead to serious liver disease. If you have liver disease, this drug can also cause salt and water retention. This can make your liver disease worse. For people with heart problems: If you have heart disease, this drug can cause salt and water retention. Both the medication and the salt and water retention can make your condition worse. If you’ve had a heart attack or heart disease in the past, ask your doctor if this drug is safe for you. For people with kidney problems: If you have kidney problems or a history of kidney disease, this drug can cause salt and water retention. Both the medication and salt and water retention can make your condition worse. For people with breast cancer: You should not take this medication if you are a man with breast cancer. This drug can make your illness worse. For people with prostate cancer: You should not take this medication if you have prostate cancer. Testosterone cypionate can make your disease worse. For people with sleep apnea (difficulty breathing during sleep): If you have sleep apnea, ask your doctor if this medication is safe for you. This drug can make this condition worse. You may wake up more frequently at night, which can make you more tired during the day. For people with polycythemia (high red blood cell count): This drug can significantly increase your red blood cell count and make your condition worse. You should not use this medication if your hematocrit is above 54%. For people with high cholesterol: This drug can raise your cholesterol levels. High cholesterol can increase your risk of heart or blood vessel problems. Your doctor will monitor your cholesterol levels while you are taking this medication. For people with diabetes: This drug can cause a significant drop in your blood sugar levels. Your doctor may lower the dose of your diabetes medication. You may also need to monitor your blood sugar levels closely. For people with blood clots: This drug may increase your risk of developing blood clots in your lungs or in the deep veins of your legs, especially if you have had blood clots in the past. Warnings for other groups For pregnant women: Testosterone cypionate is a category X pregnancy drug. Category X drugs should never be used during pregnancy. This drug should only be used in men. For seniors: This drug should not be used to treat age-related testosterone decline. There isn’t enough information from clinical trials in the elderly 65 years and older to support the long-term use of this drug. If you are older than 65 you may be at higher risk of heart disease, prostate cancer and an enlarged prostate while taking this drug. For children: Testosterone cypionate has not been confirmed to be safe and effective for use in children under the age of 12. Testosterone cypionate can affect bone growth in children. This drug can cause bones to mature faster than normal without an increase in height. This can result in a shorter adult height. Your doctor will check your child’s growth regularly if your child is taking this medicine.
How to take Testosterone Cypionate? All possible dosages and dosage forms may not be included here. Your dosage, form of administration and how often you take the medicine will depend on: Your age
the disease to be treated
how severe your condition is
other medical conditions you have
how you react to the first dose Dosage forms and strengths Generic: Testosterone cypionate Form: injectable solution
Solution for injection Strengths: 100 mg/ml, 200 mg/ml Brand: Depo-Testosterone Form: Solution for injection
Solution for injection Strengths: 100 mg/mL, 200 mg/mL Dose for primary hypogonadism Dose for adults (18 years and older) Typical starting dose: Your dose will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks.
Your dosage will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks. Dose increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your muscle every 2 weeks. Dosage for children (ages 12-17 years) Typical starting dosage: Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks.
Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks. Dose increases: Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your child’s muscle every 2 weeks. Child Dosing (Age 0-11 years) Testosterone cypionate has not been confirmed to be safe and effective for use in children under 12 years of age. Dosing for hypogonadotrophic hypogonadism Dosing for adults (18 years and older) Typical starting dose: Your dose will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks.
Your dosage will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks. Dose increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your muscle every 2 weeks. Dosage for children (ages 12-17 years) Typical starting dosage: Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks.
Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks. Dose increases: Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your child’s muscle every 2 weeks. Child Dosing (Age 0-11 years) Testosterone cypionate has not been confirmed to be safe and effective for use in children under 12 years of age. Disclaimer: Our goal is to provide you with the most relevant and up-to-date information. However, because medications affect everyone differently, we cannot guarantee that this list includes all possible dosages. This information does not replace medical advice. Always talk to your doctor or pharmacist about the right dosage for you.
Taking as directed Testosterone Cypionate Injection Solution is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you suddenly stop taking your medicine or stop taking it at all: Your medicine may not be working as well. For this drug to work well, there needs to be a certain amount in your body at all times. If you are not taking this drug, you may still have symptoms of low testosterone levels. If you miss doses or don’t take your medication on time: Your medication may not work as well or may stop working completely. For this drug to work well, there needs to be a certain amount in your body at all times. If you take too much: You could have dangerous levels of the medicine in your body. Adverse symptoms may include: acne
Pain and swelling at the injection site
hair growth
Gynecomastia (breast enlargement)
more frequent erections
Erections that last longer than normal
decrease in sperm count
mood swings
Headache If you think you have taken too much of this medication, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room immediately. What to do if you miss a dose: Call your doctor and let them know how long it has been since you last injected testosterone cypionate. They will help you create a new dosing schedule. Never try to catch up by taking two doses at once. This can lead to dangerous side effects. How to tell if the drug is working Your symptoms of low testosterone should improve and may go away.
Important Considerations When Taking Testosterone Cypionate Keep these considerations in mind if your doctor prescribes testosterone cypionate for you. General Take this medication at the times recommended by your doctor. Storage Store Testosterone Cypionate at room temperature between 68°F and 77°F (20°C and 25°C).
Keep this medication away from light. Refills A prescription for this medication may not be refillable. You may need a new prescription for this drug to be refilled. Ask your doctor about the refill status for this medication. Travel If you travel with your medication: Always carry your medication with you. Never put it in checked baggage when flying. Keep it in your hand luggage.
Don’t worry about X-ray machines at the airport. They can’t harm your medication.
You may need to show airport staff the pharmacy label of your medication. Always carry the original container marked with the prescription with you.
Do not put this medication in the glove box of your car and do not leave it in the car. Avoid doing this at all costs when the weather is very hot or very cold.
Remember to bring syringes and needles so you can inject your medication while you are away from home. Self-management Testosterone cypionate is given by injection into your muscle (usually the buttocks). Your doctor will teach you how to inject the drug deep into your muscle. What you need to buy to give yourself an injection: sterile alcohol swabs
syringes
needles
a sharps container (a bin for safely disposing of used syringes) Clinical monitoring You and your doctor should monitor certain health conditions while you are taking this medicine. This can help keep you safe during your treatment. These problems include: Cholesterol levels. This drug can raise your cholesterol levels. High cholesterol can increase your risk of heart or blood vessel problems. Your doctor will monitor your cholesterol levels while you are taking this medication.
This drug can raise your cholesterol levels. High cholesterol can increase your risk of heart or blood vessel problems. Your doctor will monitor your cholesterol levels while you are taking this medication. hemoglobin and hematocrit. In rare cases, this drug can increase your red blood cell count to very high levels. This is called polycythemia. Your doctor will check your hemoglobin and hematocrit levels to make sure they are not significantly elevated while you are taking this medication.
In rare cases, this drug can increase your red blood cell count to very high levels. This is called polycythemia. Your doctor will check your hemoglobin and hematocrit levels to make sure they are not significantly elevated while you are taking this medication. testosterone levels. Your doctor will check your total testosterone levels 3-6 months after you start taking this medication. After that, they check your testosterone levels once a year to make sure this drug is working for you. Your doctor may adjust your dosage based on your testosterone levels.
Your doctor will check your total testosterone levels 3-6 months after you start taking this medication. After that, they check your testosterone levels once a year to make sure this drug is working for you. Your doctor may adjust your dosage based on your testosterone levels. bone age. If your child is given this drug for delayed puberty, your doctor should take x-rays of your child’s wrist and hand every 6 months to check how quickly their bones are maturing.
If your child is given this drug for delayed puberty, your doctor should take x-rays of your child’s wrist and hand every 6 months to check how quickly their bones are maturing. Prostate Health. Seniors treated with this drug may be at increased risk of developing an enlarged prostate and prostate cancer. Your doctor can examine your prostate and measure your prostate-specific antigen (PSA) levels to make sure your prostate is healthy. Availability Not every pharmacy carries this drug. When you fill out your prescription, be sure to call ahead to make sure your pharmacy carries it. Hidden costs You may need to purchase: Sterile alcohol swabs
Syringes and needles for injection of testosterone cypionate
a sharps container (a container for safely disposing of used syringes) Prior Authorization Many insurance companies require prior authorization for this medication. This means that your doctor must obtain approval from your health insurance company before your health insurance company will pay for the prescription.
Is 2 ml of testosterone a week enough?
Answer. 1 ml per week is 200 mg per week of testosterone. This is a replacement dose not shown to increase lean mass significantly in the short term. However, using higher doses may also increase red blood cell production and blood viscosity, so your doctor needs to monitor your hematocrit blood levels.
Testosterone Injection: MedlinePlus Drug Information
Mine injected me 1ml Testosterone CYP per week. No improvement I gave up about a year ago. My VL went from 200 to 738 in 6 months. I started a new treatment (Stribild) and tried to go undetectable. I want to get back into my training routine and steroid use. I have your book BTS is 1ml enough to get desired results. should i dr ask to increase the amount in a 12-week cycle. I’m about 5’8″ and 159 pounds and every day someone makes a comment about how skinny I look.
answers
1ml per week is 200mg testosterone per week. This is a replacement dose that will not significantly increase lean mass in the short term. However, using higher doses can also increase red blood cell production and blood viscosity, so your doctor will need to monitor your blood hematocrit levels. Nandrolone and oxandrolone are two compounds that have been studied in isolating HIV and have fewer side effects than high-dose testosterone. They are described in detail in my book Built to Survive.
Built to survive
are you eating enough Do you train with weights or machines? These factors are just as important or more important than using hormones to gain weight and lean mass.
Please let me know if you have any further questions. I hope you regain the weight you seem to have lost.
Nelson
How much testosterone should I take to build muscle?
Supplementation of testosterone (300-600 mg/wk) to healthy older men for 20 weeks results in skeletal muscle hypertrophy and increases relative area of both type I and II fibers and myogenin expression.
Testosterone Injection: MedlinePlus Drug Information
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Can you overdose on testosterone?
If testosterone is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
Testosterone Injection: MedlinePlus Drug Information
Testosterone is a hormone normally produced by the body. It controls the growth, development, and function of male sex organs and characteristics.
This drug is available in several topical forms for the skin, nose, and mouth that are applied to the body one to three times a day, depending on how it is administered.
This drug is also available in an injectable form that is administered directly into a muscle (IM) by healthcare professionals.
Common side effects of testosterone include irritation and redness at the application site, headache, acne, abdominal pain, nervousness, hair loss, mood and behavior changes, and changes in the ability to taste or smell.
Can testosterone cypionate freeze?
How do I store and/or throw out Testosterone Cypionate Injection? Store at room temperature. Do not freeze. Store in the original container to protect from light.
Testosterone Injection: MedlinePlus Drug Information
Generic Name: Testosterone Cypionate Injection [tes-TOS-ter-one]
Brand Name: Depo-Testosterone
Drug class: Androgenic and anabolic steroids
Medically verified by Drugs.com. Last updated on February 18, 2022.
How to use Testosterone Cypionate Injection:
It is used to treat low testosterone levels.
What do I need to tell my doctor BEFORE taking Testosterone Cypionate Injection?
If you have an allergy to Testosterone or any other part of Testosterone Cypionate Injection.
if you are allergic to testosterone cypionate injections; any part of Testosterone Cypionate Injection; or other drugs, foods or substances. Let your doctor know about the allergy and what signs you’ve had.
if you are male and have breast or prostate cancer.
If you have any of these health conditions: heart disease, kidney disease, or liver disease.
If you are a woman. This medicine is not approved for use in women. If you are a woman using testosterone cypionate injection, talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
This is not a list of every medication or health issue that interacts with Testosterone Cypionate Injection.
Tell your doctor and pharmacist about all your medications (prescription, over-the-counter, natural products, vitamins) and health problems. You need to verify that it is safe for you to take Testosterone Cypionate Injections with all your medications and health issues. Do not start, stop, or change the dose of any medication without consulting your doctor.
What do I need to know or do while taking Testosterone Cypionate Injection?
For all patients taking Testosterone Cypionate Injection:
Let all your healthcare providers know that you are taking Testosterone Cypionate Injections. This includes your doctors, nurses, pharmacists and dentists.
If you have high blood sugar (diabetes), you need to monitor your blood sugar closely.
There may be a higher risk of prostate cancer. Talk to the doctor.
If you have an enlarged prostate, your symptoms may worsen while using testosterone cypionate injections. Call your doctor if this happens to you.
Hypertension has occurred with Testosterone Cypionate Injection. Have your blood pressure checked as directed by your doctor.
High blood pressure can increase the risk of heart attack, stroke, or death from heart disease. If you have high blood pressure or heart disease, talk to your doctor.
If you have sleep apnea, talk to your doctor. Sometimes sleep apnea has worsened in people using testosterone.
Treatment with testosterone cypionate injections can lead to higher cholesterol and triglyceride levels. The impact of these changes on heart health is unknown. Talk to the doctor.
Have your blood count checked as directed by your doctor. Talk to the doctor.
This medicine can affect certain laboratory tests. Tell all your healthcare providers and lab workers that you are on Testosterone Cypionate Injections.
Blood clots have occurred with Testosterone Cypionate injection. Tell your doctor if you have ever had a blood clot. Talk to your doctor.
This drug is an anabolic steroid. Anabolic steroid drugs have previously been abused and abused. Anabolic steroid abuse can lead to addiction and very bad health problems. These health problems include heart or blood vessel problems, stroke, liver problems, and mental or mood problems. Talk to the doctor.
Some cancer patients have experienced high calcium levels with drugs like this. Call your doctor right away if you have signs of high calcium such as weakness, confusion, tiredness, headache, stomach upset or vomiting, constipation, or bone pain.
If you are 65 years or older, use Testosterone Cypionate Injection with caution. You could have more side effects.
This medicine is not approved for the treatment of age-related low testosterone levels. Talk to your doctor.
This medicine can affect sperm in men. This can affect the ability to father a child. Talk to the doctor.
Children:
Use with caution in children. Talk to the doctor.
Some products contain benzyl alcohol. Do not give a product that contains benzyl alcohol to a newborn or infant. Talk to your doctor to see if this product contains benzyl alcohol.
This medicine may in some cases affect the growth of children and adolescents. They may need regular growth checks. Talk to the doctor.
What is the best way to take this medicine (Testosterone Cypionate Injection)?
Use Testosterone Cypionate Injection as directed by your doctor. Read all the information you are given. Follow all instructions carefully.
It is given as an injection into a muscle.
If you are giving yourself the injection, your doctor or nurse will teach you how to give the injection.
Wash your hands before use.
Make sure you know where to drop off the syringe. If you are not sure where to give the injection, talk to your doctor.
Do not apply to skin that is irritated, sensitive, bruised, red, scaly, hard, scarred, or has stretch marks.
Do not use if the solution is cloudy, leaking, or contains particles.
This medicine is colorless to pale yellow. Do not use if the solution changes colour.
Dispose of needles in a needle/sharps disposal box. Do not reuse needles or other objects. When the crate is full, follow all local rules to get rid of it. Talk to a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
Use a missed dose as soon as you think about it.
If it is almost time for your next dose, skip the missed dose and go back to your normal time.
Do not use 2 doses at the same time or extra doses.
What side effects should I discuss with my doctor immediately?
WARNING/CAUTION: Although rare, some people can experience very serious, and sometimes fatal, side effects when taking a medication. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that could indicate a very serious side effect:
signs of an allergic reaction such as a rash; hives; Itching; red, swollen, blistered, or peeling skin with or without a fever; wheezing; chest or throat tightness; difficulty breathing, swallowing, or speaking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Signs of high blood pressure such as a very severe headache or dizziness, fainting or blurred vision.
In men, erections (hard penis) that occur frequently or last a long time.
Difficulty urinating, painful urination, urinating in a weak stream or dripping, or urinating more frequently.
Cannot control urination.
New or worse behavior or mood changes such as depression or suicidal thoughts.
Enlarged breasts.
chest pain.
shortness of breath, excessive weight gain, or swelling in your arms or legs.
upset stomach or vomiting.
Difficulty breathing while sleeping.
sleepiness during the day.
Weakness on one side of the body, difficulty speaking or thinking, balance problems, drooping on one side of the face, or blurred vision.
change in skin color.
Change in the size or shape of the testicles.
Call your doctor at once if you have signs of a blood clot such as chest pain or pressure; cough up blood; Shortness of breath; swelling, warmth, numbness, color change, or pain in a leg or arm; or difficulty speaking or swallowing.
Liver problems have occurred with drugs like this. Sometimes this was deadly. Call your doctor right away if you have signs of liver problems such as dark urine, tiredness, feeling hungry, upset stomach or abdominal pain, light-colored stools, vomiting, or yellow skin or eyes.
What Are Some Other Side Effects of Testosterone Cypionate Injection?
All medications can have side effects. However, many people experience little or no side effects. Call your doctor or get medical help if any of these or other side effects bother you or don’t go away:
Headache.
pimples (acne).
Diarrhea.
Emotional ups and downs.
Feeling tired or weak.
Sleep disorders.
Irritation when Testosterone Cypionate Injection is used.
These are not all of the side effects that can occur. If you have any questions about side effects, ask your doctor. Call your doctor for medical advice about side effects.
You can report side effects to the FDA at 1-800-332-1088. You can also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think you have overdosed, call your poison control center or get medical help right away. Be ready to tell or show what was taken, how much and when it happened.
How do I store and/or dispose of Testosterone Cypionate Injection?
Store at room temperature. Do not freeze.
Store in the original container in order to protect from light.
Store dry. Do not store in the bathroom.
Keep all medications in a safe place. Keep all medications out of the reach of children and pets.
Throw away unused or expired medication. Do not flush down a toilet or pour down a drain unless instructed to do so. If you have any questions about the best way to dispose of medicines, ask your pharmacist. There may be drug take-back programs in your area.
Use of Consumer Information
If your symptoms or health problems don’t get better or get worse, call your doctor.
Don’t share your medicines with others or take other people’s medicines.
Some medications may have a different leaflet. Ask your pharmacist. If you have any questions about Testosterone Cypionate Injection, please speak to your doctor, nurse, pharmacist, or other healthcare provider.
If you think you have overdosed, call your poison control center or get medical help right away. Be ready to tell or show what was taken, how much and when it happened.
frequently asked Questions
View more frequently asked questions
Further information
Always check with your doctor to ensure that the information presented on this page is appropriate for your personal circumstances.
Medical Disclaimer
How should testosterone cypionate be stored?
Storage. Store testosterone cypionate at room temperature between 68°F and 77°F (20°C and 25°C). Keep this drug away from light.
Testosterone Injection: MedlinePlus Drug Information
Important Warnings Cardiac Effects Warning: No long-term studies have been conducted to know if testosterone replacement therapy has any adverse effects on heart health in men. However, short-term studies have shown that this drug may increase your risk of heart attack, stroke, or death.
No long-term studies have been conducted to know if testosterone replacement therapy has any adverse effects on heart health in men. However, short-term studies have shown that this drug may increase your risk of heart attack, stroke, or death. Liver problems warning: Long-term use of high doses of this drug may increase the risk of liver problems. These problems include liver cancer and hepatitis. These are serious medical conditions that can be life-threatening.
Using high doses of this medicine for a long time can increase the risk of liver problems. These problems include liver cancer and hepatitis. These are serious medical conditions that can be life-threatening. Blood clots warning: This drug may increase your risk of developing blood clots in your lungs or the deep veins of your legs.
This drug can increase your risk of developing blood clots in your lungs or the deep veins of your legs. Abuse Warning: Testosterone can be abused. There is an increased risk if you take the drug in higher doses than your doctor has prescribed for you or if you use it in conjunction with other anabolic steroids. Testosterone abuse can lead to serious health problems. These problems include heart attack, heart failure, depression and psychosis. Your doctor can tell you more about the risks of testosterone abuse.
What is Testosterone Cypionate? Testosterone cypionate is a prescription drug. It is given as an injectable solution into the muscle. Testosterone cypionate is a self-injectable drug. You can give yourself this medication at home after your doctor has shown you how. Testosterone cypionate is available as the brand name drug Depo-Testosterone. It is also available as a generic. Generic drugs usually cost less than the branded version. In some cases, they may not be available in every strength or form as a branded drug. Testosterone cypionate is a controlled substance. This means that it is regulated by the government. Why it is used Testosterone cypionate is used to treat symptoms of hypogonadism in men. In this condition, men do not produce enough of the sex hormone testosterone. Low testosterone levels in men can lead to mood swings, poor concentration, erectile dysfunction (difficulty getting or maintaining an erection), and low sex drive. It can also cause decreased growth of the penis and testicles, gynecomastia (breast growth), loss of body hair and muscle mass, anemia, and osteoporosis. There are two types of hypogonadism: primary and hypogonadotropic. This drug can be used to treat both. Primary hypogonadism occurs when the testicles cannot produce enough testosterone.
occurs when the testicles cannot produce enough testosterone. Hypogonadotropic hypogonadism occurs when parts of the brain (hypothalamus or pituitary gland) that tell the testicles to produce testosterone are damaged. How it works Testosterone Cypionate belongs to a class of drugs called androgens. A drug class is a group of drugs that work in a similar way. These drugs are often used to treat similar conditions. Testosterone cypionate works to treat hypogonadism in men by replacing the testosterone that your body cannot make.
Testosterone Cypionate Side Effects Testosterone Cypionate Injectable Solution does not cause drowsiness but may cause other side effects. More Common Side Effects Some of the more common side effects of testosterone cypionate include: Acne
Pain and swelling at the injection site
hair growth
Gynecomastia (breast enlargement)
more frequent erections
Erections that last longer than normal
mood swings
headache
Decrease in sperm count when the drug is used in high doses. If these effects are mild, they may go away within a few days or a few weeks. If they get more severe or don’t go away, talk to your doctor or pharmacist. Serious side effects Call your doctor at once if you have any serious side effects. Call 911 if your symptoms feel life-threatening or if you think you have a medical emergency. Serious side effects and their symptoms may include: Heart attack. Symptoms may include the following: chest pain shortness of breath upper body discomfort
Stroke. Symptoms may include: weakness in one part or side of your body slurred speech
Enlargement of your prostate. Symptoms may include: frequent or urgent need to urinate nocturia (needing to urinate more often at night) difficulty urinating weak stream of urine, or a stream that stops and starts to dribbling at the end of urination straining to urinate not being able to empty your bladder completely
prostate cancer. Your doctor should screen for prostate cancer or prostate problems before and during treatment with this drug, especially if you are 65 years of age or older.
liver problems. Symptoms may include: feeling sick (nausea) vomiting abdominal pain and swelling swelling in your legs and ankles bruising more easily than normal pale stools unusual or unexplained tiredness loss of appetite dark-colored urine yellowing of the skin or whites of the eyes
Deep vein thrombosis (blood clots in the deep veins of the legs). Symptoms may include: swelling of your leg leg pain
pulmonary embolism (blood clots in the lungs). Symptoms may include: shortness of breath chest pain or discomfort, which gets worse if you take a deep breath or cough feeling lightheaded or dizzy or fainting fast heart rate coughing up blood
Polycythemia (increase in the number of your red blood cells). Symptoms may include the following: flushing headache confusion stroke blood clots tiredness decrease in mental alertness
Disclaimer: Our goal is to provide you with the most relevant and up-to-date information. However, because medicines affect everyone differently, we cannot guarantee that this information includes all possible side effects. This information does not replace medical advice. Always discuss possible side effects with a doctor who knows your medical history.
Testosterone Cypionate May Interact with Other Drugs Testosterone Cypionate Injectable Solution may interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To avoid interactions, your doctor should carefully manage all your medications. Be sure to tell your doctor about all medications, vitamins, or herbs you are taking. To find out how this medication might interact with something else you’re taking, talk to your doctor or pharmacist. Examples of drugs that can cause testosterone cypionate interactions are listed below. Interactions that increase the risk of side effects Taking testosterone cypionate with certain medications increases the risk of side effects from those medications. Examples of these drugs include: insulin and oral diabetes drugs such as nateglinide, pioglitazone, repaglinide, rosiglitazone, metformin, glimepiride, glipizide, sitagliptin, saxagliptin, linagliptin, exenatide, and liraglutide. Taking these medicines at the same time can lead to a significant reduction in your blood sugar levels. Your doctor may lower the dose of your diabetes medication. You may need to monitor your blood sugar levels closely while taking these medicines together.
Taking these medicines at the same time can lead to a significant reduction in your blood sugar levels. Your doctor may lower the dose of your diabetes medication. You may need to monitor your blood sugar levels closely while taking these medicines together. Oral blood thinners such as warfarin. Taking these medicines at the same time can increase the risk of bleeding. Your doctor will monitor you closely if you take these medicines together.
Taking these medicines at the same time can increase the risk of bleeding. Your doctor will monitor you closely if you take these medicines together. Corticosteroids and adrenocorticotropic hormone. Taking these drugs with testosterone cypionate puts you at greater risk of edema (fluid retention). Your doctor should monitor you closely for fluid buildup when you take these medicines together, especially if you have heart or liver problems. Disclaimer: Our goal is to provide you with the most relevant and up-to-date information. However, because medications affect everyone differently, we cannot guarantee that this information includes all possible interactions. This information does not replace medical advice. Always talk to your doctor about possible interactions with all prescription drugs, vitamins, herbs and dietary supplements, and over-the-counter medicines you are taking.
Testosterone Cypionate Warnings This drug comes with several warnings. Allergy warning Testosterone cypionate can cause a severe allergic reaction. Adverse symptoms may include the following: Difficulty breathing
Swelling of your throat or tongue If you develop these symptoms, call 911 or go to the nearest emergency room. Do not take this drug again if you have ever had an allergic reaction to it. Re-administration could be fatal (cause death). Warnings for people with certain health conditions For people with liver problems: This drug can cause liver damage. This can lead to serious liver disease. If you have liver disease, this drug can also cause salt and water retention. This can make your liver disease worse. For people with heart problems: If you have heart disease, this drug can cause salt and water retention. Both the medication and the salt and water retention can make your condition worse. If you’ve had a heart attack or heart disease in the past, ask your doctor if this drug is safe for you. For people with kidney problems: If you have kidney problems or a history of kidney disease, this drug can cause salt and water retention. Both the medication and salt and water retention can make your condition worse. For people with breast cancer: You should not take this medication if you are a man with breast cancer. This drug can make your illness worse. For people with prostate cancer: You should not take this medication if you have prostate cancer. Testosterone cypionate can make your disease worse. For people with sleep apnea (difficulty breathing during sleep): If you have sleep apnea, ask your doctor if this medication is safe for you. This drug can make this condition worse. You may wake up more frequently at night, which can make you more tired during the day. For people with polycythemia (high red blood cell count): This drug can significantly increase your red blood cell count and make your condition worse. You should not use this medication if your hematocrit is above 54%. For people with high cholesterol: This drug can raise your cholesterol levels. High cholesterol can increase your risk of heart or blood vessel problems. Your doctor will monitor your cholesterol levels while you are taking this medication. For people with diabetes: This drug can cause a significant drop in your blood sugar levels. Your doctor may lower the dose of your diabetes medication. You may also need to monitor your blood sugar levels closely. For people with blood clots: This drug may increase your risk of developing blood clots in your lungs or in the deep veins of your legs, especially if you have had blood clots in the past. Warnings for other groups For pregnant women: Testosterone cypionate is a category X pregnancy drug. Category X drugs should never be used during pregnancy. This drug should only be used in men. For seniors: This drug should not be used to treat age-related testosterone decline. There isn’t enough information from clinical trials in the elderly 65 years and older to support the long-term use of this drug. If you are older than 65 you may be at higher risk of heart disease, prostate cancer and an enlarged prostate while taking this drug. For children: Testosterone cypionate has not been confirmed to be safe and effective for use in children under the age of 12. Testosterone cypionate can affect bone growth in children. This drug can cause bones to mature faster than normal without an increase in height. This can result in a shorter adult height. Your doctor will check your child’s growth regularly if your child is taking this medicine.
How to take Testosterone Cypionate? All possible dosages and dosage forms may not be included here. Your dosage, form of administration and how often you take the medicine will depend on: Your age
the disease to be treated
how severe your condition is
other medical conditions you have
how you react to the first dose Dosage forms and strengths Generic: Testosterone cypionate Form: injectable solution
Solution for injection Strengths: 100 mg/ml, 200 mg/ml Brand: Depo-Testosterone Form: Solution for injection
Solution for injection Strengths: 100 mg/mL, 200 mg/mL Dose for primary hypogonadism Dose for adults (18 years and older) Typical starting dose: Your dose will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks.
Your dosage will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks. Dose increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your muscle every 2 weeks. Dosage for children (ages 12-17 years) Typical starting dosage: Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks.
Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks. Dose increases: Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your child’s muscle every 2 weeks. Child Dosing (Age 0-11 years) Testosterone cypionate has not been confirmed to be safe and effective for use in children under 12 years of age. Dosing for hypogonadotrophic hypogonadism Dosing for adults (18 years and older) Typical starting dose: Your dose will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks.
Your dosage will depend on your age and diagnosis. Your doctor will determine a dosage based on your needs. Generally, the dosage is 50-400 mg injected into your muscle every 2-4 weeks. Dose increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your muscle every 2 weeks. Dosage for children (ages 12-17 years) Typical starting dosage: Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks.
Your child’s dosage will depend on their age and diagnosis. Your doctor will determine a dosage based on your child’s needs. Generally, the dosage is 50-400 mg injected into your child’s muscle every 2-4 weeks. Dose increases: Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects.
Your doctor may adjust your child’s dosage based on their testosterone blood levels, response to treatment, and side effects. Maximum dose: 400 mg injected into your child’s muscle every 2 weeks. Child Dosing (Age 0-11 years) Testosterone cypionate has not been confirmed to be safe and effective for use in children under 12 years of age. Disclaimer: Our goal is to provide you with the most relevant and up-to-date information. However, because medications affect everyone differently, we cannot guarantee that this list includes all possible dosages. This information does not replace medical advice. Always talk to your doctor or pharmacist about the right dosage for you.
Taking as directed Testosterone Cypionate Injection Solution is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you suddenly stop taking your medicine or stop taking it at all: Your medicine may not be working as well. For this drug to work well, there needs to be a certain amount in your body at all times. If you are not taking this drug, you may still have symptoms of low testosterone levels. If you miss doses or don’t take your medication on time: Your medication may not work as well or may stop working completely. For this drug to work well, there needs to be a certain amount in your body at all times. If you take too much: You could have dangerous levels of the medicine in your body. Adverse symptoms may include: acne
Pain and swelling at the injection site
hair growth
Gynecomastia (breast enlargement)
more frequent erections
Erections that last longer than normal
decrease in sperm count
mood swings
Headache If you think you have taken too much of this medication, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room immediately. What to do if you miss a dose: Call your doctor and let them know how long it has been since you last injected testosterone cypionate. They will help you create a new dosing schedule. Never try to catch up by taking two doses at once. This can lead to dangerous side effects. How to tell if the drug is working Your symptoms of low testosterone should improve and may go away.
Important Considerations When Taking Testosterone Cypionate Keep these considerations in mind if your doctor prescribes testosterone cypionate for you. General Take this medication at the times recommended by your doctor. Storage Store Testosterone Cypionate at room temperature between 68°F and 77°F (20°C and 25°C).
Keep this medication away from light. Refills A prescription for this medication may not be refillable. You may need a new prescription for this drug to be refilled. Ask your doctor about the refill status for this medication. Travel If you travel with your medication: Always carry your medication with you. Never put it in checked baggage when flying. Keep it in your hand luggage.
Don’t worry about X-ray machines at the airport. They can’t harm your medication.
You may need to show airport staff the pharmacy label of your medication. Always carry the original container marked with the prescription with you.
Do not put this medication in the glove box of your car and do not leave it in the car. Avoid doing this at all costs when the weather is very hot or very cold.
Remember to bring syringes and needles so you can inject your medication while you are away from home. Self-management Testosterone cypionate is given by injection into your muscle (usually the buttocks). Your doctor will teach you how to inject the drug deep into your muscle. What you need to buy to give yourself an injection: sterile alcohol swabs
syringes
needles
a sharps container (a bin for safely disposing of used syringes) Clinical monitoring You and your doctor should monitor certain health conditions while you are taking this medicine. This can help keep you safe during your treatment. These problems include: Cholesterol levels. This drug can raise your cholesterol levels. High cholesterol can increase your risk of heart or blood vessel problems. Your doctor will monitor your cholesterol levels while you are taking this medication.
This drug can raise your cholesterol levels. High cholesterol can increase your risk of heart or blood vessel problems. Your doctor will monitor your cholesterol levels while you are taking this medication. hemoglobin and hematocrit. In rare cases, this drug can increase your red blood cell count to very high levels. This is called polycythemia. Your doctor will check your hemoglobin and hematocrit levels to make sure they are not significantly elevated while you are taking this medication.
In rare cases, this drug can increase your red blood cell count to very high levels. This is called polycythemia. Your doctor will check your hemoglobin and hematocrit levels to make sure they are not significantly elevated while you are taking this medication. testosterone levels. Your doctor will check your total testosterone levels 3-6 months after you start taking this medication. After that, they check your testosterone levels once a year to make sure this drug is working for you. Your doctor may adjust your dosage based on your testosterone levels.
Your doctor will check your total testosterone levels 3-6 months after you start taking this medication. After that, they check your testosterone levels once a year to make sure this drug is working for you. Your doctor may adjust your dosage based on your testosterone levels. bone age. If your child is given this drug for delayed puberty, your doctor should take x-rays of your child’s wrist and hand every 6 months to check how quickly their bones are maturing.
If your child is given this drug for delayed puberty, your doctor should take x-rays of your child’s wrist and hand every 6 months to check how quickly their bones are maturing. Prostate Health. Seniors treated with this drug may be at increased risk of developing an enlarged prostate and prostate cancer. Your doctor can examine your prostate and measure your prostate-specific antigen (PSA) levels to make sure your prostate is healthy. Availability Not every pharmacy carries this drug. When you fill out your prescription, be sure to call ahead to make sure your pharmacy carries it. Hidden costs You may need to purchase: Sterile alcohol swabs
Syringes and needles for injection of testosterone cypionate
a sharps container (a container for safely disposing of used syringes) Prior Authorization Many insurance companies require prior authorization for this medication. This means that your doctor must obtain approval from your health insurance company before your health insurance company will pay for the prescription.
What happens if steroids freeze?
It is concluded that repeated freezing and thawing of plasma, or storage at various temperatures have only a small effect on the measured levels of steroids and their plasma binding. Although it is not advisable, even whole blood may be used for the analysis of steroid concentrations.
Testosterone Injection: MedlinePlus Drug Information
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How To Properly Store Testosterone // What to do If Crystalize
See some more details on the topic how to fix crystallized testosterone here:
Why Does Testosterone Crystallise? – The Men’s Health Clinic
Yes, it’s a pain to resolve and yes, you will need to warm your cypionate up prior to injecting if crystals are present, however please rest …
Source: themenshealthclinic.co.uk
Date Published: 3/12/2021
View: 4141
Top 12 How To Fix Crystallized Testosterone
Top 12 How To Fix Crystallized Testosterone · 1. Crystallized Test Vial, and How to handle bringing it back · 2. TRANSITION BLOG — Testosterone Crystallizing and …
Source: thuvienhoidap.net
Date Published: 5/8/2021
View: 3811
Crystallized Test Vial, and How to handle bringing it back
Simply get yourself a pot. · Fill the pot up with water that comes up to half way on your vial. · Turn on heat to medium (do not let it boil).
Source: www.secretsofbodybuilding.org
Date Published: 7/25/2022
View: 1964
best way to fix crystallized gear? – Getbig.com
Even the testosterone cypionate I get from the pharmacy eventually crystalizes. You don’t have to put it in boiling water to fix it though.
Source: www.getbig.com
Date Published: 4/29/2022
View: 3077
Testosterone Cypionate Storage Warning – Defy Medical
If your Testosterone cypionate has crystalized, it will likely be opaque or cloudy and contain small, needle-shaped crystals. Injecting the separated …
Source: www.defymedical.com
Date Published: 8/25/2022
View: 2992
TRANSITION BLOG — Testosterone Crystallizing and Pain…
I’ve recently learned that Testosterone Cypionate (the stuff most transmen use for HRT) crystallizes when stored below 59 degrees fahrenheit (15 …
Source: nickbehr.tumblr.com
Date Published: 12/23/2021
View: 2503
Best way to fix crystallized gear? – The Iron Den
I just put a cup of water in the microwave and bring to a boil, remove and place the vial in there. Only use enough water so the vial does not …
Source: www.theironden.com
Date Published: 12/8/2021
View: 827
What to Do With Crystalized Test – Pharma – Forums – T Nation
Everyone knows you smoke crystal test. Actually heating it in water on the stove is a good way. Then bring the temperature down slowly to try to …
Source: forums.t-nation.com
Date Published: 1/20/2021
View: 8594
Injectable T & Crystallization : r/ftm – Reddit
You can try dissolving the crystals by using a hair dryer or putting it on a radiator or something. People will also microwave water so that …
Source: www.reddit.com
Date Published: 9/17/2022
View: 9333
PROBLEM: Test Cyp is crystalizing in bottle | MESO-Rx Forum
The less Cyp that was left, the more Cyp seemed to turn into crystals. Last week I noticed that quite a bit had crystalized and there was only …
Source: thinksteroids.com
Date Published: 3/2/2022
View: 4886
Why Does Testosterone Crystallise?
Testosterone Cypionate is more prone to satiety compared to Testosterone Enanthate. This makes it more prone to crystallization under certain avoidable circumstances, which will be explained in more detail later.
Cypionate manufacturers worldwide have universal advice to screen your testosterone drug for crystal particles prior to administration (1-3). If crystals are present, they recommend warming and shaking the solution to dissolve them. Research reports have reassuringly confirmed that this process does not negatively affect testosterone in any way (4)(5).
Below is a “simple” description of the differences between Testosterone Cypionate and Testosterone Enanthate. I will not describe in detail how crystals can form nor their structural configurations as it is lengthy. Note the following image that represents the structure of Testosterone Cypionate or Testosterone Enanthate (click for full size):
The esters covalently attach to the rightmost oxygen atom of the testosterone steroid. The structure is completely different, although chemically speaking the esters only differ by one carbon atom. This structural difference, in addition to changing the stereochemistry (note the ester positioning and this is a 2D image!), will greatly affect several factors such as: B. the ability to form crystals. For one thing, Testosterone Cypionate has two less-rotatable bonds, which severely affects Testosterone’s ability to bind to other Testosterone molecules in a crystal formation. This doesn’t even include the number of electrons and other structural considerations. Small changes can have big effects. I’ll leave it at that so we don’t go into too much detail about the chemistry.
One of the biggest contributors to crystal formation is supersaturation, ie. too much of a solute. Think too many teabags in your tea making it taste too strong! To counteract this, manufacturers often increase the volume of Testosterone Cypionate to 125 mg/ml (250 mg/2 ml). The next factor is temperature; a temperature that exceeds the threshold for crystal formation will actually cause crystal formation. The other factor is just bad luck – if you already have a crystal and shake this solution, it’s more likely to ‘hit’ other testosterone molecules and possibly bind to them and form a crystal – the temperature is ideal and the conditions are such a crystal configuration can be formed. Add in the fact that users often force air into their testosterone vial when drawing up their medication and we just compress the solution more, which can mean a higher chance of crystal formation occurring.
We can really go into depth here with the actual chemistry behind it, but we won’t because it’s complex. The bottom line is that it can happen, which is why manufacturers are changing the concentration to minimize this risk. Also, that’s not to say it can’t happen with other testosterone supplements, there are papers describing the same thing with other esters like propionate (6). Unfortunately, there’s not much we can do against the laws of physics, but the bottom line is that these drugs are clinically approved and the crystals won’t harm you. Yes, it’s a hassle to dissolve and yes, you need to warm up your cypionate before injecting if crystals are present. However, rest assured that this will not affect your testosterone replacement therapy.
You can reduce the risk of crystals forming in your Testosterone Cypionate by following the advice below:
Do not shake the vial unnecessarily (handle gently and carefully when transporting).
When traveling, store carry-on baggage instead of putting it in the hold (temperatures in the hold can be significantly lower than the cabin temperature).
Make sure not to inject air into the vial while preparing and drawing up your testosterone. Sometimes when you take it out of the sealed package, there will be a small amount of air in the syringe, make sure that all of this air is expelled BEFORE inserting it into the vial. Please email us if you need links to instructional videos on how to prepare and take your testosterone medication.
References:
1. https://www.sandoz.ca/sites/www.sandoz.ca/files/10033-Testosterone%20Cypionate%20Injection%20USP%20Product%20Monograph.pdf
2. https://www.medsafe.govt.nz/Profs/Datasheet/d/Depotestosteroneinj.pdf
3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/085635s029lbl.pdf
4. https://pfe-pfizercom-prod.s3.amazonaws.com/products/hcp_depotestosterone.pdf
5. https://www.sunpharma.com/sites/default/files/customer-letter-pdf.pdf
6. https://pubs.acs.org/doi/10.1021/cg200640g
Testosterone Cypionate Storage Warning
What is Testosterone Cypionate?
You may be wondering what Testosterone Cypionate is and why it is prone to crystallization along with other exposure issues.
Testosterone is a male sex hormone (also called an androgen) that is responsible for many functions throughout the body. These include:
maintenance of body composition
Promotion of muscle growth
Regulating Mood
Libido and sex drive support
Supporting healthy sexual function
Many men and women suffer from testosterone deficiency, which can lead to sexual dysfunction, reduced quality of life, and other testosterone deficiency symptoms. Low testosterone can occur for many reasons, but the most common is the result of reduced testosterone production due to aging.
Testosterone Replacement Therapy (TRT) is a treatment that replenishes testosterone levels to reduce deficiency symptoms and optimize hormone levels for a better quality of life.
Testosterone Cypionate is an injectable form of testosterone that contains a cypionate ester. Esters are chains of hydrogen, carbon, and oxygen that bind to testosterone, essentially making it take longer to break down in the body – creating a timed release.
Testosterone esters are important because without them, the body would metabolize testosterone very quickly, causing testosterone levels to spike and then drop precipitously. This would lead to uncomfortable hormone fluctuation symptoms.
Testosterone Cypionate is a longer acting ester that is metabolized in around 7-8 days making it ideal for many patients. It is commonly used in TRT protocols and is usually injected weekly.
Due to Testosterone Cypionate’s chemical makeup and concentration, it is susceptible to degradation or crystallization when exposed to temperatures outside of Testosterone’s recommended storage temperature range of 68° – 77°F. It is also susceptible to chemical degradation from exposure to UV light.
It is important to store Testosterone Cypionate as recommended to avoid crystallization and degradation and to follow the directions outlined in this article if your Testosterone Cypionate vial is exposed to any of these elements.
Depending on the type of exposure, your injection may be painful or your medication may stop working effectively, which could negatively impact your TRT protocol and cause your hormone deficiency symptoms to return.
If you are a patient at Defy Medical, you can contact Patient Services at 813-445-7342 or [email protected] to discuss any concerns you may have about taking medication. We gladly support you.
Testosterone Injection: MedlinePlus Drug Information
Testosterone undecanoate injection (Aveed) can cause severe breathing problems and allergic reactions during or immediately after the injection. The injection should be given by a doctor or nurse in a medical facility that can treat these problems or reactions. You must remain at the medical facility for at least 30 minutes after receiving your injection. Tell your doctor or nurse right away if you experience any of the following symptoms during or after the injection: tight throat, trouble breathing, trouble swallowing, shortness of breath, coughing or coughing, chest pain, dizziness, fainting, sweating, rash, hives, or itching .
A program has been put in place to limit the use of testosterone undecanoate injections (Aveed) and to educate people about the increased risk of breathing problems and allergic reactions while taking this drug. The program also ensures that anyone who has received this drug understands the risks and benefits of this drug and receives the drug in an environment where they can be monitored for any serious reactions.
Testosterone Enanthate Injection (Xyosted) and other testosterone products can cause a rise in blood pressure, which can increase your risk of a heart attack or stroke, which can be life-threatening. Tell your doctor if you have or have ever had high blood pressure, heart disease, a heart attack, or stroke. Tell your doctor and pharmacist if you are taking medication for blood pressure, pain, or cold symptoms. If you experience any of the following symptoms, contact your doctor immediately: chest pain; Shortness of breath; pain in your arms, back, neck, or jaw; slow or difficult speech; dizziness or fainting; or weakness or numbness of an arm or leg.
Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly.
Your doctor or pharmacist will give you the manufacturer’s patient information (medication guide) when you start treatment with testosterone undecanoate injection or testosterone enanthate injection (Xyosted). Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website for the Medication Guide.
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