Top 20 How Much Is Tren The 139 Top Answers

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Although lots of bodybuilders and athletes use Tren, it’s illegal to do so. In the USA, the Drug Enforcement Administration (DEA), classes it as a Schedule III controlled substance. Using Schedule III drugs may lead to moderate to low physical dependence and/or high psychological dependence.Trenbolone results typical

You can expect to gain 10-15lbs of lean mass if you use trenbolone in bulk. This is a 4-week cycle. You could gain 25-30lbs in an 8-week cycle.Most people find an underground lab that makes liquid injectable Trenbolone but it is against the law to do so. Also against the law is to purchase the Finaplex pellets which are intended for livestock. Even buying the paraphernalia required to convert the pellets into an injectable liquid is technically illegal.

Trenbolone acetate

Size	Price	Quantity
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Bulk Size	Bulk Discount
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Free Overnight Delivery on orders over $ 500 Next day delivery by 10:00 a.m. Order now.

It has strong anabolic effects and highly androgenic effects, as well as potent progestogenic effects, and weak glucocorticoid effects. Trenbolone acetate is an androgen ester and a long-lasting prodrug of trenbolone in the body.
…
Trenbolone acetate.

Clinical data
CAS Number	10161-34-9
PubChem CID	66359
DrugBank	DB14660
ChemSpider	17468428

Contents

Is Tren legal in USA?

How fast does TREN work?

Trenbolone results typical

You can expect to gain 10-15lbs of lean mass if you use trenbolone in bulk. This is a 4-week cycle. You could gain 25-30lbs in an 8-week cycle.

Can you buy trenbolone?

Most people find an underground lab that makes liquid injectable Trenbolone but it is against the law to do so. Also against the law is to purchase the Finaplex pellets which are intended for livestock. Even buying the paraphernalia required to convert the pellets into an injectable liquid is technically illegal.

Is Tren a strong steroid?

Clinical data
CAS Number	10161-34-9
PubChem CID	66359
DrugBank	DB14660
ChemSpider	17468428

What are the side effects to Tren?

Trenbolone’s androgenic qualities cause typical side effects. These include greasy skin, breakouts, seborrheic dermatitis, excessive growth of facial hair, and rapid scalp hair loss. Men prone to hair loss-related disorders such as baldness have a greater probability of experiencing premature baldness.

Where can I buy anabolic steroids?

You can also buy anabolic steroids from an online pharmacy that is based outside the US, but the shipment must be done from the US.
…
For example, if you live in the United States, then you can buy steroids from any of the following websites:

CrazyBulk.
CrazySteroids.
CrazyMuscle.
CrazyMass.

How long can you run TREN for?

300 to 500mg per week for 10-12 weeks is considered an effective Tren cycle for intermediate users, combined with at least one other compound such as testosterone propionate for 12 weeks.

Does Tren make you sweat?

“It’s a very controversial study,” wrote Christopher Wohlforth of Massachusetts General Hospital in an e-mail. “The data are not in for a decade, and it’s being treated as scientific proof of the efficacy of Tren, trenbolone side effects night sweats.

How much does trenbolone acetate cost?

Trenbolone acetate

Size	Price	Quantity
25mg	USD 97	0 1 2 3 4 5 6 7 8 9 10
Bulk Size	Bulk Discount
Add to Cart Bulk Inquiry
Free Overnight Delivery on orders over $ 500 Next day delivery by 10:00 a.m. Order now.

How much trenbolone should I take a week?

Most beginners would do well with 50mg every other day of Trenbolone Acetate (for a total of 200mg weekly) and is more than enough for staving off muscle loss during a cut. Some people find using more Trenbolone Acetate (500mg or higher) improves the effectiveness of the treatment.

How do you inject trenbolone?

Injecting into a muscle step by step

Draw up with a green needle, then swap to a blue for injecting.
Insert the needle at 90 degrees to your body. …
Draw the plunger back slightly to check you haven’t hit a vein or artery. …
Only inject up to 2ml of fluid into each site – if you inject more it raises your risk of infection.

What is the best anabolic steroid?

Top 5 Best Anabolic Steroids for Muscle Growth in 2022:

D-Bal – Overall Best Legal Steroids for Sale; Natural Steroids Online.
D-Bal MAX – Trusted Steroid Bodybuilders for Muscle Gain.
Brutal Force – DBULK Dianabol – Top Muscle Enhancers & Bulking Steroids.

How much trenbolone should I take a week?

Does Tren increase testosterone?

The trenbolone further increases testosterone levels and muscle growth without causing an overabundance of estrogen in the body. This is why research shows that animals given trenbolone along with estrogen generally grow muscle faster and end up leaner than animals only given trenbolone.

How often do I inject Tren enanthate?

This medication is given by injection into the buttock muscle as directed by your doctor, usually every 1 to 4 weeks. Do not inject this medication into a vein. Dosage is based on your medical condition, testosterone blood levels, and response to treatment.

Tren for TRT, how much tren is too much? Ask the Anabolic Doc Ep. 42

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Table of Contents:

What is Trenbolone (Tren Steroid)

Trenbolone Types

What is Trenbolone Acetate

What is Trenbolone Enanthate

What is Trenbolone Hexahydrobenzylcarbonate

Is Trenbolone Legal – A Look at the Legal Issues

Who Makes Trenbolone

Why is Trenbolone So Popular

Trenbolone Cycle

Trenbolone Results (Before and After Cycles)

Massive Muscle Growth

Fat Loss and Cutting

Rapid Recovery

Endurance

Zero Aromatization

How to Get the Best Before and After Results from Tren Cycles

Trenbolone Steroid Cycle Side Effects

Acne

Male Pattern Baldness

High Cholesterol Levels and Increases In Blood Pressure

Gynecomastia

Increases In Visceral Fat

Anxiety Aggression and Depression

Testosterone Suppression

Where to Buy Trenbolone Steroids Online and In Store

Best Legal Trenbolone Alternatives

Crazy Bulk Trenorol Review An Evaluation of the Best Legal Trenbolone Pills

Crazy Bulk Trenorol Ingredients

Crazy Bulk Trenorol Benefits

Where to Buy Legal Trenbolone Steroids Online

Trenorol vs Trenbolone Which is Best

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Trenbolone before and after

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Table of Contents:

What is Trenbolone

Trenbolone Steroid Introduction

What is the Difference Between Trenbolone and Tren

Injectable Trenbolone Acetate

Trenbolone – Benefits to the Bodybuilder Athlete

Trenbolone Side Effects

How to Use Trenbolone for Bodybuilding

Best Tren Cycle

What Other Steroids Can be Stacked With Trenbolone

Trenbolone Conclusion and Recommendations

Trenbolone Results – How Quickly Does it Work

How to Buy Legal Trenbolone

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Table of Contents:

Contents

Uses[edit]

Side effects[edit]

Pharmacology[edit]

Chemistry[edit]

History[edit]

Society and culture[edit]

References[edit]

Trenbolone before and after

Trenbolone before and after

Trenbolone is one the most potent steroids on the market. It is an excellent steroid for building muscle.

You may be asking yourself, “What can tren do?” It’s possible!

The short answer is no. So let’s know more about trenbolone before and after.

It is a very anabolic drug that can be used to burn fat. This makes trenbolone a great choice for cutting and bulking. Because it can add large amounts of lean mass to the body (without water retention), it is more popular during the offseason.

It is a bulking steroid that can also be used for cutting. The great thing about tren is its ability to reduce muscle mass and neutralize any catabolic effects associated with eating in a calorie deficit.

Trenbolone is also diuretic. It will make it more frequent to use the bathroom.

You will appear more toned by your body’s ability to flush out extracellular fluids like this.

After completing a tren program, your gains in muscle mass and fat loss will be permanent. A small amount of water may be lost after your tren cycle. This is the diuretic effect that wears off.

Trenbolone results typical

You can expect to gain 10-15lbs of lean mass if you use trenbolone in bulk. This is a 4-week cycle.

You could gain 25-30lbs in an 8-week cycle. Side effects can be more common the longer trenbolone is used.

FDA considers Trenorol safe and will not cause any side effects.

You might see the following visuals on tren:

Enhanced vascularity

Increased sweating

A reduction in water, under the skin, results in a thinner skin.

Skin that is reddish or flushed

Bigger pumps

Trenbolone can be used during a cut to help you lose fat.

While you won’t be able to lose as much fat as with other cutting steroids such as anavar and/or clenbuterol it will be noticeable. Trenbolone has such anabolic properties that it will likely help you build muscle while cutting.

Trenbolone results

Trenbolone users are often easy to spot because their bodies are so distinctive. Because certain muscle groups are visible, like traps and the deltoids in their bodies, they appear ‘photoshopped’. These muscles are more susceptible to muscle growth due to their high number of androgen-receptors.

Because trenbolone is an extremely androgenic drug, it causes the muscles of these two to explode.

Due to the low amount of water outside of the muscle cells, it is much easier to get striations with trenbolone. When your body fat is less than 6%, striations are likely to occur.

How to Maximize Trenbolone Performance

If you’re looking for a way to make your body incredibly lean, trenbolone can be stacked with the following steroids.

Clenbuterol

Anavar

Anavar and clenbuterol can help you shed a lot of fat, compared to trenbolone.

You can stack trenbolone with these bulking steroids if you are looking to bulk.

Dianabol

Testosterone

Deca

The testosterone and trenbolone cycles work well for people who don’t want any water retention. This is also known as a dry cycle or ‘dry gain’. Because your gains are muscle-based, you will lose weight almost immediately after you have completed such a cycle.

If you’re looking to boost your muscle gains, you can also add deca or dianabol. Although not very noticeable, these two steroids can result in water retention.

Combining anadrol and trenbolone is not a good idea unless you have a lot of experience. This is because the 2 anabolics are very harsh on the body.

Trenbolone Steroid Cycle: Tren Results, Before and After, Buy Legal Tren

Looking to get incredible results with your next steroid cycle? Look no further than trenbolone. This powerful anabolic steroid can help you achieve muscle growth, fat loss, and improved strength like never before. I will highlight trenbolone results, before and after results, how to use, and where to buy legal tren online.

But before talking Trenbolone, you should be aware how it works and what side effects to watch out for. We will tell you how to best use Trenbolone for bodybuilding – including how to stack with other steroids and if you need a PCT – as well as where to BUY LEGAL TRENBOLONE ONLINE.

Where to Buy Legal Tren

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Trenorol mimics the androgenic effects of Trenbolone producing positive muscle building effects without the risk of side effects.

Increase muscle growth

Speeds up muscle gains

Increase strength and power

Great all round conditioner

Trenorol can be stack with D-Bal, DecaDuro and Testo Max to form a bulking stack – great for bulking up and packing on the muscle mass

When these steroids are stacked together, they can create an incredibly powerful muscle-building environment.

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What is Trenbolone?

Steroid Name: Trenbolone Acetate

aka: Tren, Fina, Finaplex, Finaject, Finajet, Parabolan

Forms: Liquid injectable (Finaplex is an ear plug for cattle but must be converted to injectable acetate for human use)

Trenbolone Mostly Used For: Bulking, Cutting, Strength – it is a very versatile steroid

Trenbolone Steroid Introduction

Trenbolone Acetate is considered by many professional bodybuilders to be the best anabolic steroid ever synthesized. Talk to different users at different gyms and you will get varying stories about Tren and what it can and can’t do.

It’s gained a lot of attention in the past – as most steroids have – but it’s also retained a kind of mystique as the steroid that seems to be able to do everything.

If you want to know the hard facts about Trenbolone, and not the broscience and nonsense being shouted at you by some acne-ridden dude by the benchpress, continue reading…

What is the Difference Between Trenbolone and Tren?

Trenbolone is also known as its shortened form, Tren, but it’s more widely recognized as “Fina ” after the first brand names it traded under; Finajet and Finaject. These were veterinary grade steroids first synthesized in the 1960s.

A pharmaceutical version called Parabolan was manufactured with an ester attachment, which was the only chemical alteration to the animal grade Fina.

Parabolan would be the only human grade cut of Trenbolone but it didn’t make it, ultimately succumbing to the same fate as most anabolic steroids, and was discontinued in the late ‘90s. The vet-grade Trenbolone Acetate that had come out of the ‘60s had been stopped in the ‘80s, even before the human grade stuff, but it made a reappearance as Finaplex.

Finaplex came in the form of pellets which were placed in the ears of cattle to dissolve and improve the lean tissue before slaughter day.

Injectable Trenbolone Acetate

Bodybuilders and athletes have used this pellet form of Trenbolone by making an injectable Trenbolone Acetate. This is still practiced by some people but the black market has also advanced in more recent years and there are pre-prepared injectable forms of Trenbolone Acetate.

Trenbolone Acetate is a favorite because it outstrips other steroids at bulking, cutting and strength cycles. We’ll look into that more in the next section.

Trenbolone – Benefits to the Bodybuilder / Athlete

Trenbolone is five times the anabolic and androgenic ratings of testosterone due to a simple alteration to its structure.

It also binds very tightly to the androgen receptor while having low aromatization activity. It is also a fairly fast acting steroid.

It’s a lot like other steroid from an anabolic standpoint, it promotes:

Nitrogen Retention

Protein Synthesis

IGF-1 Production

Red Blood Cell production

Muscle Hardness, Strength, Vascularity

All of the above create an anabolic environment in muscle tissue, and Trenbolone appears to accomplish this more potently compared to most if not all other anabolic steroids.

In terms of cutting fat, Trenbolone binds tightly to the Androgen Receptor (AR) and by doing so can trigger direct fat burning and inhibit cortisol based hormones.

Cortisol is known as the stress hormone, and it can create a catabolic environment (muscle breakdown) especially during dieting phases and cutting cycles.

Trenbolone can be used during a bulking cycle, as is evidential from its anabolic traits, however it is also used during a cutting cycle due to its:

Cortisol Inhibition

Direct Fat Burning

What makes it particularly useful is the combination of its anabolic and fat burning traits. People tend to lose some muscle during a cutting cycle no matter what but Tren can reduce the catabolic state.

So for the person bulking, it will prevent them from adding on body fat mass, and for the person in a cutting cycle it will improve muscle retention.

Finally, Trenbolone increases the uptake of nutrients from food. This is due to the demands it puts on the body by increasing all the other aspects of anabolism and androgenicity. Diet therefore becomes an extremely important part of any cycle that includes Trenbolone Acetate.

Trenbolone Side Effects

Like any anabolic androgenic steroid, Trenbolone users should be prepared for the possibility of side effects. Although it is a lot more potent than most steroids with respect to its anabolic and cutting benefits, it is not necessarily true of its side effects.

The negative side effects of Trenbolone don’t include estrogenic effects such as excess water retention but it can cause:

Gynecomastia (man boobs)

The gynecomastia is not a result of aromatization of the Tren but the progesterone promotion of it which can trigger breast tissue to grow.

When used in combination with other aromatizing steroids this side effects can become worse. Users tend to need estrogen blockers as part of their on-cycle therapy.

Androgenic Side Effects of Trenbolone

Androgenic side effects are possible given Trenbolone’s affinity to the androgen receptor. These include:

Acne

Male Pattern Baldness, i.e. an accelerated rate if predisposed

Some people who use Tren need not worry about baldness if they are not predisposed to it.

Cardiovascular Tren Side Effects

Cardiovascular problems can arise in the form of:

Increased LDL (aka, bad cholesterol)

Increased Blood Pressure

Other side effects of Trenbolone include:

Testosterone Suppression – Trenbolone’s suppression of natural testosterone production is strong compared to most steroids, perhaps with the exception of Deca Durabolin (Nandrolone). Deca can shut down natural testosterone production in one shot. Steroid users usually take exogenous (synthetic) testosterone in some form in order to supply the body with some testosterone and prevent themselves from entering a low testosterone state, a condition which can be extremely bad for health.

Anxiety

Insomnia

Night Sweats

Heart Palpitations

The last four side effects there are known as “response effects” which are the effects particular to a steroid, in this case Trenbolone Acetate. There is nothing life threatening there but they can be severe and can sometimes be the reason a person stops using Trenbolone even if they experience no other negative effects.

How to Use Trenbolone for Bodybuilding

It’s important to remember that Trenbolone has not been approved for human use and so there can’t really be said to be an optimal usage guideline.

Most people find an underground lab that makes liquid injectable Trenbolone but it is against the law to do so.

Also against the law is to purchase the Finaplex pellets which are intended for livestock. Even buying the paraphernalia required to convert the pellets into an injectable liquid is technically illegal.

Hopefully you will also forgive us if we do not give explicit dosage information for using Trenbolone Acetate. The steroid – any steroid – can have different effects on different people and where some men can tolerate 100mg every other day, others would find 50mg every other day more than enough. Trenbolone acetate’s concentration is 75mg/ml of liquid.

Trenbolone is a very powerful steroid, and it can have potent side effects if the user does not tolerate it well. It goes without saying that caution must be assumed every step of the way with anabolic steroids, not to mention the peripheral issues of needle use and hygiene.

With the exception of testosterone, trenbolone is probably the most popular anabolic steroid on the black market. While it sounds like an easy thing to purchase, the more popular a steroid is the more chance there is of coming across counterfeit gear that is either garbage or dangerous. Neither option is good nor worth risking your neck over.

Best Tren Cycle

It is essential that users take care when cycling trenbolone. The first step is to make sure that you are in good health before beginning a cycle.

Trenbolone can put a lot of strain on your heart and lungs, so it is important to get a checkup from your doctor before starting. Once you have been cleared for use, you will need to slowly increase your dosage over the course of several weeks.

Start with a low dose and increase it gradually, monitoring your side effects closely. If you experience any negative effects, stop using trenbolone immediately and consult your doctor.

Be sure to end your cycle slowly, tapering off your dosage over a period of several weeks. This will help your body adjust back to its normal hormone levels and minimize the risk of side effects. Cycling trenbolone can be safe and effective if done carefully. Follow these guidelines to ensure that you stay healthy while using this powerful steroid.

When cycling trenbolone, it is important to start with a low dose and gradually increase the dose over the course of the cycle. Trenbolone should not be used for more than 8 weeks at a time. It is also important to use a proper PCT (post cycle therapy) protocol after cycling trenbolone.

What Other Steroids Can be Stacked With Trenbolone?

There are a few different steroids that can be stacked with Trenbolone to create an even more powerful and effective effect.

One option is to stack Trenbolone with Dianabol (or Dbol). Dbol pills are a very fast-acting steroid that helps to increase protein synthesis, leading to increased muscle mass. It also has the ability to increase nitrogen retention, which helps to create an anabolic environment in the body.

Another option is to stack Trenbolone with Anadrol. Anadrol is another fast-acting steroid that increases protein synthesis and nitrogen retention. It also has the ability to increase red blood cell production, which leads to improved oxygenation of the muscles.

Trenbolone can also be stacked with Winstrol. Winstrol is a slower-acting steroid that helps to increase lean muscle mass and strength. It also has the ability to increase vascularity and definition. When these three steroids are stacked together, they create an incredibly powerful and effective muscle building effect.

Trenbolone Conclusion and Recommendations

Trenbolone Acetate is one of the most popular and potent anabolic steroids available to black market buyers because it is so versatile, slotting into cutting cycles and bulking cycles and easily being the most potent steroid in the stack. During both phases it can increase strength incredibly.

However, it is also illegal and can have severe side effects depending on the tolerance level of the individual using it.

The steroid comes in two forms: a liquid which must be injected intramuscularly, most likely every other day for the cycle duration, and solid cattle ear plugs under the name Finaplex. An injectable acetate form can be made from the ear plugs, but this can often cause confusion for the person doing it.

Underground labs tend to make a prepared liquid form, however underground labs are also unscrupulous more often than not.

An important consideration is that someone using Tren must also inject Testosterone due to the potency of Tren’s testosterone suppression. They are also likely to need estrogen blockers and possibly even Finasteride, or another 5-AR blocker to prevent too much conversion to DHT (to prevent premature balding) however this has not been shown to be overly effective.

Together with on cycle medication to mitigate the potential side effects there is a course of Post Cycle Therapy that will be required. And on top of all this is the risk of cardiovascular side effects.

If you wish to purchase a legal and safe oral anabolic steroid which is the alternative to Trenbolone, follow the link below and you can find out more.

Trenbolone Results – How Quickly Does it Work?

In terms of how quickly trenbolone works, studies have shown that it can help to increase muscle mass and strength within just a few weeks of use.

In one study, participants who used trenbolone for eight weeks were able to gain an average of 5.5 kilograms of muscle mass. So, if you are looking for a quick way to boost your muscle-building results, tren may be worth considering.

How to Buy Legal Trenbolone

If you wish to buy Trenbolone in a safe oral pill form that is also legal, try looking at Trenorol from the company Crazybulk.

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Trenbolone acetate

Chemical compound

Trenbolone acetate, sold under brand names such as Finajet and Finaplix among others, is an androgen and anabolic steroid (AAS) medication which is used in veterinary medicine, specifically to increase the profitability of livestock by promoting muscle growth in cattle.[2][3][4][5] It is given by injection into muscle.[5][6]
Side effects of trenbolone acetate include symptoms of masculinization like acne, increased body hair growth, scalp hair loss, voice changes, and increased sexual desire.[5] The drug is a synthetic androgen and anabolic steroid[7] and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).[5][6][8] It has strong anabolic effects and highly androgenic effects, as well as potent progestogenic effects, and weak glucocorticoid effects.[5][6][8][9][10] Trenbolone acetate is an androgen ester and a long-lasting prodrug of trenbolone in the body.

Trenbolone acetate was discovered in 1963 and was introduced for veterinary use in the early 1970s.[5][11][12] In addition to its veterinary use, trenbolone acetate is used to improve physique and performance, and is purchased from black market suppliers.[5] The drug is a controlled substance in many countries and so non-veterinary use is generally illicit.[5]
Uses [ edit ]
Veterinary uses [ edit ]
A single cartridge of Finaplix-H containing 10 implants. Each implant contains 10 small yellow pellets. (Image Adapted from Medi-Vet Animal Health, LLC ( https://www.medi-vet.com/Finaplix-H-p/16301.html )).

In the livestock industry, trenbolone acetate is more often called Finaplix. It was intentionally developed to promote androgen and gain muscle mass in cattle. Due to its properties, this allows livestock to grow as much muscle as possible before they are transported to a slaughterhouse.

Methyl cellulose and yellow dye are usually present in pellets given to livestock. A single dosage generally consists of 10 pellets, and a package of Finaplix usually consists of one cartridge, which contains 100 pellets (See Figure). This is usually given to the animal by means of a subcutaneous injection into the posterior location of the ear (See Figure) with the use of an implanter gun. Finaplix is consistently implanted until the animal is ready to be slaughtered. There is no withholding period. Due to the common practice of trenbolone acetate use in veterinary medicine, it is quite common to find traces of trenbolone metabolites in cattle worldwide.[11][13]
Image showing the general area of the implantation of Finaplix-H pellets displayed on bovine ear.

Non-medical uses [ edit ]
Bodybuilding [ edit ]
Trenbolone acetate was never approved for use in humans and therefore guidelines for human consumption do not exist.[5] However, athletes and bodybuilders have been using trenbolone acetate as a physique- and performance-enhancing drug for decades. There are a large number of benefits as a bodybuilder through using trenbolone acetate as an AAS. Unlike testosterone, trenbolone acetate does not cause any fluid retention while gaining muscle mass.[11] This allows bodybuilders to appear leaner, and this is why it is more commonly used whilst preparing for competitive events. Trenbolone acetate does not convert into an estrogenic metabolite,[11] and this results in a lack of estrogenic side effects.[5] Trenbolone enanthate is also a very commonly used AAS and lasts much longer than trenbolone acetate with intramuscular injection.[5]
Medical uses [ edit ]
Trenbolone acetate was never approved for use in humans and hence has no medical uses.[5] However, as an AAS, it would be expected to be effective for indications in which other AAS are useful such as the treatment of conditions like androgen deficiency, wasting syndromes and muscle atrophy, and certain types of anemia.[5][14]
Trenbolone actually was produced for human use as a human grade product, but only once. The product came in 1.5ml ampoules consisting of 76.2mg of Trenbolone hexahydrobenzylcaronate and made by Negma Pharmaceuticals of France.[citation needed]
Side effects [ edit ]
Trenbolone acetate, like any other AAS, has many side effects.[15][16][17] The strong androgenic nature of trenbolone acetate facilitates its tendency to produce virilization[15] and this is why it is not recommended for women for physique- or performance-enhancing purposes.[5] The side effects of trenbolone acetate are similar to other AAS; however, the negative side effects that are specifically facilitated by trenbolone acetate are as follows.

Androgenic [ edit ]
Trenbolone acetate has androgenic activity.[18][19][20] Specific to the androgenic properties of trenbolone, common side effects of the AAS use include oily skin, acne, seborrhea, increased facial/body hair growth, and accelerated scalp hair loss.[5][15][21] These side effects strongly rely on an individual’s genetics and may not always occur in every individual. Men susceptible to hair loss related illnesses, such as baldness have a higher chance of becoming permanently bald with the use of trenbolone acetate.[15] In women, voice deepening, hirsutism, clitoral enlargement, and virilization in general may occur.[5]
Hypogonadism [ edit ]
Trenbolone acetate contributes greatly to muscle mass and feed efficiency; however, administration of the AAS suppresses natural testosterone production; i.e., it has the potential to cause hypogonadism.[5][16][21] This is a common effect of all AAS; the only difference is the variation in how much they suppress in comparison to others.

Cardiovascular [ edit ]
Administration of any AAS can lead to cardiovascular issues.[22] Trenbolone acetate can have a negative and strong impact on cholesterol through suppressing both high-density lipoprotein (HDL) cholesterol and increasing low-density lipoprotein (LDL) cholesterol.[23] When compared to oral AAS, trenbolone acetate has a stronger negative effect on cholesterol levels. This negative effect is much more severe with the use of injectable AAS, particularly trenbolone acetate.[24]
The exact mechanisms underlying the cause of the tren cough is not known. However, trenbolone acetate’s androgenic effect activates a variety of lipid-like active compounds which are called prostaglandins.[25] Many of these prostaglandins are inflammatory and vasoconstrictive. Prostaglandins are signalled through two varying pathways cyclooxygenase (COX) (Also known as: prostaglandin-endoperoxide synthase) and lipoxygenases (LOX) (also known as: EC 1.13.11.34, EC 1.13.11.33, etc.).[26] The bradykinin peptide is well known to promote a cough reaction associated with ACE inhibitor medications prescribed for hypertension.[27]
Estrogenic and progestogenic [ edit ]
No form of trenbolone, including trenbolone acetate, is estrogenic.[5] Excess fluid retention is not possible with the administration of this AAS as a result of its not being estrogenic as opposed to testosterone.[5] However, due to trenbolone’s potent progestogenic activity, gynecomastia, which is characterized by development and swelling of breast tissue,[28] may still be possible.[citation needed] Stimulation of estrogenic mechanisms are enforced by progestogenic activity[citation needed] as trenbolone acetate and its compounds bind with high affinity to the progesterone receptor.[11][20] It has been assumed that gynecomastia as a result of trenbolone use is due to a buildup of the hormone prolactin;[28] however, a variety of studies conclude that it is the progestogenic activity of trenbolone promoting this and not prolactin.[citation needed] Trenbolone also has a negative impact on blood pressure, but it does not appear to negatively affect most healthy adult men in this way.[citation needed]
Pharmacology [ edit ]
Pharmacodynamics [ edit ] [29] The administration of the trenbolone hormone promotes a direct anabolic effect on Androgen Receptor (AR) activity. AR activity facilitated by trenbolone contributes to an increase in IGF-1 and IGF-1R levels, which then enhances skeletal muscle protein accretion. Activation and proliferation of satellite cells then facilitate an increase in skeletal muscle growth.

Trenbolone acetate is a prodrug of trenbolone.[6][5] Like other AAS, trenbolone is an agonist of the androgen receptor (AR) and hence has anabolic and androgenic activity as well as antigonadotropic activity.[5][6][9][30] Trenbolone carries a rating for both anabolic potency and androgenic potency of 500, relative to a standard of nandrolone acetate (rating 100 for both).[5][16] In addition to its anabolic and androgenic activity, trenbolone is an agonist of the progesterone receptor (PR), and in relation to this, has moderate to strong progestogenic activity.[5][9][30] Conversely, trenbolone acetate is not a substrate for aromatase and hence lacks estrogenic activity.[5][6][9] The compound also has weak glucocorticoid activity.[9][10]
Similar to many other AAS, trenbolone acetate has the capability to produce insulin-like growth factor-1 (IGF-1).[31][32] This naturally produced protein-based hormone affects every cell in the body of an organism and plays a large role in muscle recovery and rejuvenation. Extreme muscle growth and cell splitting compared is facilitated through trenbolone acetate administration when compared to other AAS.[31] The facilitation of IGF-1 plays a significant role in the functions and properties of the central nervous system, pulmonary system, muscle tissue, ligaments, cartilage, and tendons.[32]
Trenbolone acetate also has the ability to increase red blood cell count. With a larger amount of red blood cells, blood oxygenation is enhanced. This allows for enhanced muscular endurance and therefore promotes a faster rate of recovery. Trenbolone acetate is capable of inhibiting glucocorticoids such as cortisol.[citation needed] The properties of glucocorticoid are the opposite of androgens as muscle tissue depletion and fat gain is promoted.[33] Administration of trenbolone acetate aims at decreasing the production of glucocorticoid hormones. Trenbolone acetate’s contribution to feed efficiency, also known as nutrient efficiency is what makes it an attractive AAS used for agricultural purposes. Food is one of the most anabolic substances that any living organism can consume, and therefore with the administration of trenbolone acetate, every nutrient in the body becomes a lot more valuable.[34] This facilitates an organism’s body that is exposed to the AAS to make better use of the nutrients already consumed.[11][34]
Pharmacokinetics [ edit ]
The acetate ester of trenbolone acetate allows for slow release post injection. This ester gives trenbolone an activated elimination half-life of about 3 days.[1]
Chemistry [ edit ]
Trenbolone acetate, or trenbolone 17β-acetate, is a synthetic estrane steroid and a derivative of nandrolone (19-nortestosterone).[5][35][36] It is the C17β acetate ester of trenbolone, which itself is δ9,11-19-nortestosterone (δ9,11-19-NT) or estra-4,9,11-trien-17β-ol-3-one.[5][35][36] Other trenbolone esters include trenbolone enanthate, trenbolone hexahydrobenzylcarbonate, and trenbolone undecanoate.[5][35][36]
Structure–activity relationships [ edit ]
Trenbolone acetate is a modified form of nandrolone.[18] The structure of trenbolone acetate is a 19-nor classification, which represents a structural change of the testosterone hormone. Trenbolone acetate lacks a carbon atom at the 19 position and carries a double bond at carbons 9 and 11. The position of these carbons slows its metabolism, which greatly increases its binding affinity to the AR, and inhibits it from undergoing aromatization into the corresponding estrogenic metabolite. Trenbolone acetate contains trenbolone modified with the addition of a carboxylic acid ester (acetic acid) at the 17β-hydroxyl group.[11] This facilitates the slow release of the AAS from the area of injection.

History [ edit ]
Trenbolone acetate was first synthesized in 1963 and approved by the livestock industry as a growth promoter for beef cattle in the early 1970s.[5][11][12] During this period of its first administration, trenbolone acetate was sold under the names Finajet and Finaject. The original manufacturer of trenbolone acetate discontinued during the late 1980s and administered the synthesis of subcutaneous pellets called Finaplix. These pellets aimed to increase muscle mass and lean tissue of cattle prior to slaughter to increase the profitability of livestock when measured in total pounds of meat sold.[11]
The drug appears to have been an early development project of Roussel Uclaf, a French pharmaceutical company, and by the early 1970s, it was being sold as an injectable.[20] There are a number of trenbolone esters but trenbolone acetate is the only one known to be produced in veterinary AAS manufacturers.

Trenbolone acetate became popular among bodybuilders and athletes during the early 1980s. During this period, the AAS was transported illegally from Europe in large quantities. Although trenbolone acetate was very popular for a short amount of time, the large amounts of supplies were discontinued in 1987.[11] This decision was based upon the public concern of sports doping and its negative effects on athletes.[5]
Society and culture [ edit ]
Generic names [ edit ]
Trenbolone acetate is the generic name of the drug and its USAN , USP , and BANM .[3][4][35][36]
Brand names [ edit ]
Trenbolone acetate is or has been sold alone for veterinary use under the brand names Component TH, Component TS, Finaject, Finajet, Finaplix-H, and Finaplix-S.[3][4][5][35][36] It is or has also been sold in combination with estradiol or estradiol benzoate for veterinary use under the brand names Revalor and Synovex.[3][4][5][35][36]
Distribution and regulation [ edit ]
Trenbolone acetate, specifically referred to as Finaplix in the livestock industry, is available to purchase in veterinary drug markets.[5] A typical cartridge usually comes in the form of 20 mg pellets. It generally comes in the form of implant pellets containing 20 mg of trenbolone acetate each.[35] Preparations containing trenbolone acetate remain rare since its decline in production after the 1980s. Using AAS for any other purpose, or without a doctor’s prescription, is illegal in most countries. Major sporting and bodybuilding organizations ban the use of controlled AAS, and the possession or sale of drugs can lead to arrest and conviction of drug-trafficking in many countries, including the United States and Australia. However, in the United Kingdom, owning AAS for personal use as a bodybuilding supplement is not illegal, but selling the AAS without a valid medical license or reason is still against the law.[37]
Doping in sports [ edit ]
Regardless of their legality, AAS are still banned by most sporting leagues in the country, who routinely conduct drug tests to find the users of any AAS. There are known cases of doping in sports with trenbolone acetate by professional athletes.

References [ edit ]
Further reading [ edit ]

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