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Quetiapine is used alone or together with other medicines to treat bipolar disorder (depressive and manic episodes) and schizophrenia. Quetiapine extended-release tablet is also used together with other antidepressants to treat major depressive disorder.Quetiapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.Data synthesis: Quetiapine is commonly used off-label for treatment of insomnia. When used for sleep, doses typically seen are less than the Food and Drug Administration-recommended dosage of 150-800 mg/day; those evaluated in the studies reviewed here were 25-200 mg/day).
Contents
What’s Quetiapine used for?
Quetiapine is used alone or together with other medicines to treat bipolar disorder (depressive and manic episodes) and schizophrenia. Quetiapine extended-release tablet is also used together with other antidepressants to treat major depressive disorder.
What class of drug is Quetiapine?
Quetiapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.
Can you use Quetiapine for sleep?
Data synthesis: Quetiapine is commonly used off-label for treatment of insomnia. When used for sleep, doses typically seen are less than the Food and Drug Administration-recommended dosage of 150-800 mg/day; those evaluated in the studies reviewed here were 25-200 mg/day).
Is quetiapine the same as Xanax?
Seroquel (quetiapine) and Xanax (alprazolam) are used to treat psychiatric disorders. Seroquel is used to treat schizophrenia, major depression, and bipolar disorder. Xanax is prescribed to treat panic attacks and anxiety disorders. Seroquel and Xanax belong to different drug classes.
Can quetiapine make you crazy?
Interaction or overdosage may cause serotonin syndrome (symptoms include mental status changes [such as agitation, hallucinations, coma, delirium], fast heart rate, dizziness, flushing, muscle tremor or rigidity, and stomach symptoms [including nausea, vomiting, diarrhea]).
Is 25mg of quetiapine a lot?
However, the dose is usually not more than 750 mg per day. Children 13 to 17 years of age—At first, 25 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day.
How much quetiapine should I take to sleep?
Quetiapine dosage for sleep
When used to treat insomnia, it’s usually low-dose quetiapine, between 25 mg and 100 mg taken at bedtime. Quetiapine causes sedation quickly after taking it, so it’s recommended to take it close to bedtime.
Does quetiapine calm you down?
Quetiapine is an antipsychotic that calms and sedates, helping to relieve psychotic thoughts and manic and depressive behavior. Sedation, low blood pressure, and weight gain are common side effects.
Does quetiapine make you happy?
It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.
What drugs should not be taken with quetiapine?
- Anti-arrhythmic drugs such as quinidine, procainamide, amiodarone or sotalol.
- Antipsychotic drugs such as ziprasidone, chlorpromazine, or thioridazine.
- Antibiotics such as gatifloxacin or moxifloxacin.
- Pentamidine.
- Methadone.
Is quetiapine a opioid?
Quetiapine drug class is not a narcotic. Even though there are some people who misuse it, its classification is not related to opium or its derivatives.
What drug puts you to sleep instantly?
About zolpidem
Zolpidem is a sleeping pill. It’s used to treat insomnia (when you might have trouble getting to sleep and staying asleep). It helps you fall asleep more quickly and makes you less likely to wake up during the night.
Is quetiapine good for anxiety?
It has been most extensively studied as treatment for generalized anxiety disorder (GAD). Three trials that involved >2,100 patients found quetiapine XR monotherapy is effective for GAD in doses of 50 to 300 mg/d. In 2 of the studies, quetiapine XR was as effective as paroxetine and escitalopram for GAD.
Can you drink alcohol on quetiapine?
Avoid drinking alcohol or using illegal drugs while you are taking quetiapine. They may decrease the benefits (e.g. worsen your confusion) and increase adverse effects (e.g. sedation) of the medication.
Does quetiapine calm you down?
Quetiapine is an antipsychotic that calms and sedates, helping to relieve psychotic thoughts and manic and depressive behavior. Sedation, low blood pressure, and weight gain are common side effects.
What does quetiapine do to your mood?
It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.
How will quetiapine make me feel?
Taking quetiapine may make you feel tired or dizzy, and may affect your eyesight when you start taking it. This could affect you if you drive a car, ride a bike, or do anything else that needs a lot of focus. It might be best to stop doing these things for the first few days, until you know how it affects you.
Is quetiapine good for anxiety?
It has been most extensively studied as treatment for generalized anxiety disorder (GAD). Three trials that involved >2,100 patients found quetiapine XR monotherapy is effective for GAD in doses of 50 to 300 mg/d. In 2 of the studies, quetiapine XR was as effective as paroxetine and escitalopram for GAD.
Quetiapine (Oral Route) Side Effects – Mayo Clinic
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Description and Brand Names
Before Using
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Precautions
Side Effects
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How to pronounce quetiapine (Seroquel) (Memorizing Pharmacology Flashcard) – YouTube
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Quetiapine: MedlinePlus Drug Information
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IMPORTANT WARNING
Why is this medication prescribed
How should this medicine be used
Other uses for this medicine
What special precautions should I follow
What special dietary instructions should I follow
What should I do if I forget a dose
What side effects can this medication cause
What should I know about storage and disposal of this medication
In case of emergencyoverdose
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Brand names
Safety of low doses of quetiapine when used for insomnia – PubMed
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- Most searched keywords: Whether you are looking for Safety of low doses of quetiapine when used for insomnia – PubMed Updating There are potential safety concerns when using low-dose quetiapine for treatment of insomnia. These concerns should be evaluated in further prospective studies. Based on limited data and potential safety concerns, use of low-dose quetiapine for insomnia is not recommended.pmid:22510671, doi:10.1345/aph.1Q697, Review, Holly V Coe, Irene S Hong, Antipsychotic Agents / administration & dosage, Antipsychotic Agents / adverse effects*, Antipsychotic Agents / therapeutic use, Dibenzothiazepines / administration & dosage, Dibenzothiazepines / adverse effects*, Dibenzothiazepines / therapeutic use, Dose-Response Relationship, Drug, Humans, Quetiapine Fumarate, Sleep Initiation and Maintenance Disorders / drug therapy*, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE
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How to Pronounce Quetiapine (Seroquel) Correctly
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How to Pronounce Quetiapine (Seroquel) Correctly
Drug Pronunciation » quetiapine (Seroquel) · The generic name ‘Quetiapine’ is pronounced: · The brand name ‘Seroquel’ is pronounced:. Pronunciation guide (phonetic spelling and recorded audio) of quetiapine, also known as Seroquel, which is a Top 250 Drug in the drug class of Atypical antipsychotic.quetiapine,Seroquel,how to, pronounce, pronunciation, how to say, how to pronounce, phonetic, guide, audio, Atypical antipsychotic - Table of Contents:
Drug Pronunciation » quetiapine (Seroquel)
The generic name ‘Quetiapine’ is pronounced
The brand name ‘Seroquel’ is pronounced
Quetiapine Definition & Meaning | Merriam-Webster Medical
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Quetiapine (Oral Route) Side Effects
Description and Brand Names
Drug information provided by: IBM Micromedex
US Brand Name
SEROquel SEROquel XR
Descriptions
Quetiapine is used alone or together with other medicines to treat bipolar disorder (depressive and manic episodes) and schizophrenia. Quetiapine extended-release tablet is also used together with other antidepressants to treat major depressive disorder. This medicine should not be used to treat behavioral problems in older adult patients who have dementia or Alzheimer disease. Quetiapine is an antipsychotic medicine that works in the brain.
This medicine is available only with your doctor’s prescription.
This product is available in the following dosage forms:
Tablet, Extended Release
Tablet
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of quetiapine extended-release tablets and tablets in children with schizophrenia younger than 13 years of age, in children with bipolar mania younger than 10 years of age, and in children with bipolar depression. Safety and efficacy have not been established in these age groups.
Appropriate studies have not been performed on the relationship of age to the effects of quetiapine extended-release tablets to treat major depressive disorder in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of quetiapine in the elderly. However, elderly patients are more likely to have dementia or age-related heart, liver, or kidney problems, which may require caution and an adjustment in the dose for patients receiving quetiapine.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Bepridil
Bromopride
Cisapride
Dronedarone
Fluconazole
Lefamulin
Levoketoconazole
Mesoridazine
Metoclopramide
Pimozide
Piperaquine
Posaconazole
Potassium Citrate
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Ziprasidone
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Aclidinium
Alfentanil
Alfuzosin
Alprazolam
Amantadine
Amiodarone
Amisulpride
Amitriptyline
Amoxapine
Anagrelide
Anisotropine
Apomorphine
Aripiprazole
Aripiprazole Lauroxil
Arsenic Trioxide
Asenapine
Astemizole
Atazanavir
Atropine
Azithromycin
Bedaquiline
Belladonna
Belzutifan
Benzhydrocodone
Benztropine
Biperiden
Boceprevir
Bornaprine
Bromazepam
Brompheniramine
Buprenorphine
Bupropion
Buserelin
Butorphanol
Butylscopolamine
Calcium Oxybate
Cannabidiol
Carbamazepine
Carbinoxamine
Carisoprodol
Ceritinib
Cetirizine
Chloroquine
Chlorpheniramine
Chlorpromazine
Cimetropium
Ciprofloxacin
Citalopram
Clarithromycin
Clemastine
Clidinium
Clobazam
Clofazimine
Clomipramine
Clonazepam
Clozapine
Cobicistat
Codeine
Conivaptan
Crizotinib
Cyclobenzaprine
Cyclopentolate
Cyproheptadine
Dabrafenib
Daridorexant
Darifenacin
Darunavir
Dasatinib
Degarelix
Delamanid
Desipramine
Deslorelin
Deutetrabenazine
Dexmedetomidine
Dicyclomine
Dihydrocodeine
Dimenhydrinate
Diphenhydramine
Disopyramide
Dofetilide
Dolasetron
Domperidone
Donepezil
Doxepin
Doxylamine
Droperidol
Duvelisib
Ebastine
Efavirenz
Emepronium
Encorafenib
Entrectinib
Enzalutamide
Eribulin
Erythromycin
Escitalopram
Esketamine
Famotidine
Fedratinib
Felbamate
Fentanyl
Fesoterodine
Fexinidazole
Fingolimod
Flavoxate
Flecainide
Flibanserin
Fluoxetine
Fluphenazine
Formoterol
Foscarnet
Fosnetupitant
Fosphenytoin
Fostemsavir
Gabapentin
Gabapentin Enacarbil
Galantamine
Gatifloxacin
Gemifloxacin
Glasdegib
Glucagon
Glycopyrrolate
Glycopyrronium Tosylate
Gonadorelin
Goserelin
Granisetron
Halofantrine
Haloperidol
Histrelin
Homatropine
Hydrocodone
Hydromorphone
Hydroquinidine
Hydroxychloroquine
Hydroxyzine
Hyoscyamine
Ibutilide
Idelalisib
Iloperidone
Imipramine
Indinavir
Inotuzumab Ozogamicin
Ipratropium
Isopropamide
Itraconazole
Ivabradine
Ivosidenib
Ketamine
Ketoconazole
Lapatinib
Larotrectinib
Lemborexant
Lenvatinib
Leuprolide
Levocetirizine
Levofloxacin
Levorphanol
Lofexidine
Lopinavir
Lorlatinib
Loxapine
Lumacaftor
Lumefantrine
Macimorelin
Magnesium Oxybate
Mebeverine
Meclizine
Mefloquine
Mepenzolate
Meperidine
Methadone
Methantheline
Methixene
Methotrimeprazine
Methscopolamine
Metronidazole
Mifepristone
Milnacipran
Mirtazapine
Mitotane
Mizolastine
Mobocertinib
Moricizine
Morphine
Morphine Sulfate Liposome
Moxifloxacin
Nafarelin
Nalbuphine
Nefazodone
Nelfinavir
Netupitant
Nilotinib
Nirmatrelvir
Norfloxacin
Nortriptyline
Octreotide
Ofloxacin
Olanzapine
Ondansetron
Orphenadrine
Osilodrostat
Osimertinib
Oxaliplatin
Oxitropium Bromide
Oxybutynin
Oxycodone
Oxymorphone
Ozanimod
Pacritinib
Paliperidone
Panobinostat
Papaverine
Paroxetine
Pasireotide
Pazopanib
Pentamidine
Pentazocine
Periciazine
Perphenazine
Phenytoin
Pimavanserin
Pinaverium
Pipamperone
Pipenzolate Bromide
Pirenzepine
Pitolisant
Ponesimod
Potassium Oxybate
Pregabalin
Probucol
Procainamide
Prochlorperazine
Procyclidine
Promethazine
Propafenone
Propantheline
Propiverine
Protriptyline
Quinidine
Quinine
Ranolazine
Remifentanil
Remimazolam
Revefenacin
Ribociclib
Rifampin
Risperidone
Ritonavir
Ropeginterferon Alfa-2b-njft
Scopolamine
Selpercatinib
Sertindole
Sertraline
Sevoflurane
Siponimod
Sodium Oxybate
Sodium Phosphate
Sodium Phosphate, Dibasic
Sodium Phosphate, Monobasic
Solifenacin
Sorafenib
Sotalol
St John’s Wort
Stramonium
Sufentanil
Sulpiride
Sunitinib
Tacrolimus
Tamoxifen
Tapentadol
Telaprevir
Telavancin
Telithromycin
Terodiline
Tetrabenazine
Thiothixene
Tiotropium
Tizanidine
Tolterodine
Toremifene
Tramadol
Trazodone
Triclabendazole
Trifluoperazine
Trihexyphenidyl
Trimethobenzamide
Trimipramine
Triptorelin
Tropicamide
Trospium
Umeclidinium
Valethamate
Vandetanib
Vardenafil
Vemurafenib
Venlafaxine
Vilanterol
Vinflunine
Voclosporin
Voriconazole
Vorinostat
Zolpidem
Zuclopenthixol
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Aprepitant
Fosaprepitant
Warfarin
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
Grapefruit Juice
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
Ethanol
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Blood vessel or circulation problems or
Dehydration or
Heart attack or stroke, history of or
Heart disease (eg, heart hypertrophy) or
Heart failure or
Heart rhythm problems (eg, QT prolongation), or
Hypotension (low blood pressure) or
Hypovolemia (low blood volume)—May cause side effects to become worse.
Bradycardia (slow heartbeat), history of or
Constipation or
Diabetes, or family history of or
Enlarged prostate or
Heart rhythm problem (eg, congenital long QT interval) or
Hyperglycemia (high blood sugar) or
Hypokalemia (low potassium in the blood) or
Hypomagnesemia (low magnesium in the blood) or
Increased pressure in the eye or
Trouble urinating, or history of—May increase risk for more serious side effects.
Breast cancer, prolactin dependent or
Cataracts or
Hyperlipidemia (high blood cholesterol or fats) or
Hyperprolactinemia (high prolactin in the blood) or
Hypertension (high blood pressure) or
Hypothyroidism (underactive thyroid) or
Liver disease or
Seizures, history of or
Trouble swallowing—Use with caution. May make these conditions worse.
Proper Use
Take this medicine exactly as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
This medicine should come with a Medication Guide. Read and follow the instructions carefully. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions.
Quetiapine tablets may be taken with or without food on a full or empty stomach. However, if your doctor tells you to take it a certain way, take it as directed.
Swallow the extended-release tablets whole. Do not break, crush, or chew it. It is best to take this medicine without food or with a light meal (approximately 300 calories).
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (extended-release tablets): For treatment of depression with bipolar disorder: Adults—At first, 50 milligrams (mg) once a day in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg per day. Children—Use and dose must be determined by the doctor. For treatment of mania with bipolar disorder: Adults—At first, 300 milligrams (mg) once a day in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children 10 to 17 years of age—At first, 50 mg once a day in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 600 mg per day. Children younger than 10 years of age—Use and dose must be determined by the doctor. For treatment of major depressive disorder (MDD): Adults—At first, 50 milligrams (mg) once a day in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg per day. Children—Use and dose must be determined by the doctor. For treatment of schizophrenia: Adults—At first, 300 milligrams (mg) once a day in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children 13 to 17 years of age—At first, 50 mg once a day in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children younger than 13 years of age—Use and dose must be determined by the doctor.
For oral dosage form (tablets): For treatment of depression with bipolar disorder: Adults—At first, 50 milligrams (mg) once a day at bedtime. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg per day. Children—Use and dose must be determined by the doctor. For treatment of mania with bipolar disorder: Adults—At first, 50 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children 10 to 17 years of age—At first, 25 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 600 mg per day. Children younger than 10 years of age—Use and dose must be determined by the doctor. For treatment of schizophrenia: Adults—At first, 25 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 750 mg per day. Children 13 to 17 years of age—At first, 25 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children younger than 13 years of age—Use and dose must be determined by the doctor.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions
It is very important that your doctor check your or your child’s progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. You may also need to have your eyes tested on a regular basis.
This medicine may add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using quetiapine.
For some patients, this medicine can increase thoughts of suicide. Tell your doctor right away if you start to feel more depressed and have thoughts about hurting yourself. Report any unusual thoughts or behaviors that trouble you, especially if they are new or are getting worse quickly. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell the doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let the doctor know if you or anyone in your family has bipolar disorder (manic-depressive illness) or has tried to commit suicide.
Quetiapine may cause drowsiness, trouble with thinking, trouble with controlling body movements, or trouble with your vision (especially during the first week of use), which may lead to falls, fractures, or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
This medicine may increase the amount of sugar in your blood. Check with your doctor right away if you have increased thirst or urination. If you have diabetes, the results of your urine or blood sugar tests may change. Check your blood sugar closely and talk with your doctor if you have any questions.
Check with your doctor right away if you have convulsions (seizures), difficulty breathing, a fast heartbeat, high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).
Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor.
Quetiapine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:
If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.
Check with your doctor immediately if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.
Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.
Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.
Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.
Avoid contact sports or other situations where bruising or injury could occur.
This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.
Quetiapine may increase your cholesterol and fats in the blood. If this condition occurs, your doctor may give you medicine to lower the cholesterol and fats in the blood.
This medicine may increase your weight. Your doctor may need to check your weight on a regular basis while you are using this medicine.
You will need to have your blood pressure measured before starting this medicine and while you are using it. If you notice any changes to your recommended blood pressure, call your doctor right away. If you have questions about this, talk to your doctor.
This medicine can cause changes in your heart rhythm, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects. Contact your doctor right away if you have symptoms of heart rhythm problems, such as a fast, pounding, or uneven heartbeat.
Quetiapine may make it more difficult for your body to cool down. It might reduce how much you sweat. Your body could get too hot if you do not sweat enough. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might vomit or have an upset stomach. Do not get too hot while you are exercising. Avoid places that are very hot. Call your doctor if you are too hot and can not cool down.
Do not suddenly stop taking this medicine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This will decrease the chance of having withdrawal symptoms such as nausea, vomiting, insomnia, dizziness, irritability, or headache.
Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests (eg, urine drug screens) may be affected by this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John’s wort) or vitamin supplements.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Chills cold sweats confusion dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position sleepiness or unusual drowsiness
Less common
Black, tarry stools blurred vision changes in patterns and rhythms of speech chest pain cough drooling fever inability to move the eyes inability to sit still increased blinking or spasms of the eyelid lip smacking or puckering loss of balance control mask-like face muscle aches need to keep moving painful or difficult urination puffing of the cheeks rapid or worm-like movements of the tongue restlessness shakiness in the legs, arms, hands, or feet shuffling walk slowed movements slurred speech sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stiffness of the arms or legs sweating swelling of the face, arms, hands, feet, or lower legs swollen glands trembling and shaking of the hands and fingers trouble with breathing, speaking, or swallowing uncontrolled chewing movements uncontrolled movements of the arms and legs uncontrolled twisting movements of the neck, trunk, arms, or legs unusual bleeding or bruising unusual facial expressions unusual tiredness or weakness
Rare
Dry, puffy skin fast, pounding, or irregular heartbeat loss of appetite menstrual changes unusual secretion of milk (in females) weight gain
Incidence not known
Aching or discomfort in the lower legs or sensation of crawling in the legs agitation bed-wetting blistering, peeling, or loosening of the skin bloating bluish lips or skin chest discomfort constipation dark urine decreased awareness or responsiveness decreased urine output depression diarrhea difficulty breathing difficulty in passing urine (dribbling) difficulty swallowing dizziness faintness general feeling of tiredness or weakness headache hives, itching, skin rash hoarseness increased thirst indigestion irritability joint or muscle pain light-colored stools loss of consciousness lower back or side pain muscle cramps, spasms, stiffness, or twitching nausea painful or prolonged erection of the penis painful urination pains in the stomach, side, or abdomen, possibly radiating to the back puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue red skin lesions, often with a purple center red, irritated eyes seizures severe constipation severe sleepiness severe vomiting sore throat stomach pain, continuing tightness in the chest tingling of the hands or feet unusual bleeding or bruising unusual drowsiness, dullness, or feeling of sluggishness unusual weight gain or loss upper right abdominal pain vomiting yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Abnormal vision belching decreased appetite decreased strength and energy heartburn increased appetite increased muscle tone increased sweating indigestion sneezing stomach discomfort or upset stuffy or runny nose
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Quetiapine: MedlinePlus Drug Information
Important warning for older adults with dementia:
Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as quetiapine have an increased risk of death during treatment.
Quetiapine is not approved by the Food and Drug Administration (FDA) for the treatment of behavioral problems in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking quetiapine. For more information visit the FDA website: http://www.fda.gov/Drugs
Important warning for people who have depression:
A small number of children, teenagers, and young adults (up to 24 years of age) who took medications for depression during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 10 years of age should not normally take quetiapine, but in some cases, a doctor may decide that quetiapine is the best medication to treat a child’s condition.
You should know that your mental health may change in unexpected ways when you take quetiapine or other antidepressants even if you are an adult over age 24. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.
Your healthcare provider will want to see you often while you are taking quetiapine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.
The doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with quetiapine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.
No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.
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