How To Sleep While Taking Phentermine? The 128 Correct Answer

Correct Usage

Drug information provided by: IBM Micromedex

Only take this medicine as directed by your doctor. Don’t take more of it, don’t take it more often, and don’t take it longer than your doctor tells you to. If you take too much of this medicine it can become dependent (causing mental or physical dependence).

This medicine comes in four forms: capsules, disintegrating tablets, extended-release capsules, and tablets. Carefully follow the dosage instructions for the form you are using.

Swallow the prolonged-release capsule whole. Do not crush, break or chew.

Take the disintegrating tablet with or without food. Make sure your hands are dry before touching the tablet. Put the tablet on your tongue immediately after removing it from the bottle. It should melt quickly. After the tablet has melted, swallow or take a sip of water.

Swallow the tablet whole. Do not crush, break or chew.

Carefully follow your doctor’s instructions for a reduced-calorie eating plan and regular exercise. Talk to your doctor before starting an exercise program.

To avoid trouble sleeping, take the last dose of the day about 4 to 6 hours before bedtime unless your doctor tells you otherwise.

dosage

The dose of this medicine is different for different patients. Follow your doctor’s or label directions. The information below only includes the average doses of this drug. If your dose is different, don’t change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. Also, the number of doses you take each day, the length of time between doses, and how long you take the medicine depend on the medical problem you are using the medicine for.

To treat obesity: For the oral dosage form (capsules): Adults and children 17 years and older – 15 to 30 milligrams (mg) taken once a day, about 2 hours after breakfast. Children under 16 years of age – Use is not recommended. For the oral dosage form (disintegrating tablets): Adults and children 17 years and older – One tablet taken once a day, in the morning. Children under 16 years of age – Use is not recommended. For oral dosage form (extended release capsules): Adults and children 16 years and older – Take one capsule once daily before breakfast or 10 to 14 hours before bed. Children under 15 years of age – Use is not recommended. For oral dosage form (tablets): Adults and children 17 years and older – Lomaira™: Take one tablet 30 minutes before meals, three times daily. Phentermine: 18.75 to 37.5 milligrams (mg) once daily taken before breakfast or 1 to 2 hours after breakfast. Children under 16 years of age – Use is not recommended.

missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Don’t double the doses.

storage

Store the medicine in a closed container at room temperature away from heat, moisture and direct light. Keep from freezing.

Keep away from children.

Do not keep any medicines that are outdated or no longer needed.

Ask your doctor how to throw away medicines you no longer use.

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Phentermine can help you shed those unwanted pounds

Phentermine is the leading diet pill in the US and can help both men and women achieve desired weight loss results quickly. To get the most out of your recipe, you should know what you need to do to get the most out of your recipe. We’ve created a four-point guide to help you get the weight loss results you want.

1. Drink water to optimize Phentermine

Drinking water can really help you lose weight with phentermine. It can also help you lose weight fast. Our bodies need water to function properly and when you drink water it keeps your body running at peak levels. It can help by boosting your metabolism and helping you burn fat. Often our body thinks it’s hungry when it’s actually thirsty – our brain has trouble distinguishing between the two feelings. So it’s a good idea to drink water first before eating because you might not even be hungry. Drinking water is a great way to fill up without calories and to curb your appetite. While you should be drinking water throughout the day, it’s recommended that you have a glass 20 minutes before eating to help your stomach recognize the feeling of fullness – this way you’re actually eating less at mealtime.

In the first week of taking phentermine, users will often experience rapid weight loss from drinking water – this is your water weight that is lost. If you eat a high-sodium diet or don’t drink enough water, your body will retain that water in your body. resulting in larger numbers on the scale. So staying hydrated and drinking plenty of water is beneficial to both your body’s needs and your weight loss goal!

One of the most common side effects of phentermine is dry mouth; So, drinking water will help you relieve your dry mouth.

2. Eating right can work wonders when combined with Phentermine

While phentermine suppresses your appetite, it is very important that you need to eat in order to lose weight. You can determine the exact amount you need based on your weight, age, height and gender. Your doctor can help you design a personalized diet that meets your needs. But as a starting point, you should never eat fewer than 1,200 calories a day. If you eat fewer than 1,200 calories a day, your metabolism begins to slow; This means your body stores food instead of burning it for energy. In other words, you won’t be able to lose weight!

But it’s not just any food your body needs. To lose weight fast, you need to eat healthy meals and healthy snacks throughout the day. Your diet should include foods high in fiber, protein, fruits, vegetables, and healthy fats; combined these all work simultaneously to help your body burn fat, build muscle, limit swelling and lose weight fast with phentermine.

Most healthy foods also optimize the effects of phentermine by allowing the active ingredients to stay in your body longer; which allows you to lose weight fast with Phentermine. Healthy foods make the pH of your urine more alkaline, which causes phentermine to be slowly released into your body; allowing your body to benefit more from phentermine. You will feel the extra energy and appetite suppression longer throughout the day. On the other hand, foods high in preservatives, saturated fat, salt, sugar, and alcohol can make your urine pH more acidic and cause your body to release phentermine faster — meaning you won’t get the full benefit of yours Treatment with phentermine.

3. Cardio and Weights Might Enhance Your Phentermine Plan

Eating a healthy diet and taking phentermine can help you shed unwanted weight, but when you combine it with exercise, it can give you that extra boost you need and help target problem areas. While it’s great to do exercises you love, cardio and weight lifting are key. Cardio and weight lifting will help you tone your body. By toning your body, you build lean muscle mass. Lean muscle mass helps burn calories and boost metabolism even when you’re sleeping – which can help you lose weight faster with phentermine.

4. Healthy lifestyle is the key to Phentermine

A healthy lifestyle is often the missing piece between good and great. In order to really be successful with phentermine and lose weight fast, your body needs to be healthy. That means getting enough sleep, eating right, exercising, and remembering to relax and reduce stress.

Most people don’t realize how important sleep is. Not only can sleep help you relieve stress, but it can actually help you lose weight. Insomnia can be a common side effect of phentermine, so you really need to make sure you’re getting enough sleep.

Along with getting enough sleep, you should make sure you’re getting all your vitamins. Vitamins are crucial to keeping the good nutrients in your body. When your body is at its peak, you will see the best results from taking phentermine.

If you’re ready to see how Phentermine can transform your dieting or weight loss efforts, then call us today at (720) 534-2333 or fill out our contact form and we’ll get back to you as soon as possible all to answer your Phentermine-related questions!

A balanced, calorie-restricted diet and regular exercise are the cornerstones of weight loss, but certain medications can provide powerful support. One of these drugs is phentermine – one of the most popular weight loss drugs worldwide. It has been shown to be effective for short-term weight loss when used in conjunction with a calorie-restricted diet and exercise. However, using phentermine for weight loss is not without its risks and side effects. This article explains everything you need to know about phentermine, including its benefits, dosage, and potential side effects. Share on Pinterest Nadasaki/Getty Images

What is phentermine? Phentermine is a prescription weight loss drug. The Food and Drug Administration (FDA) approved it for short-term use of up to 12 weeks for people over the age of 16 in 1959 (1). In the 1990s, drug companies combined phentermine with other weight loss drugs. This drug combination was commonly referred to as Fen-Phen. After reports of significant heart problems among users, the FDA pulled the other two drugs used in the treatment — fenfluramine and dexfenfluramine — from the market (2). Today, phentermine can be used alone and is available under the brand names Adipex-P, Lomaira, and Suprenza. You can also find it in combination weight loss medications, such as Qsymia, which combines phentermine and another drug called topiramate. Phentermine is a stimulant and is available by prescription. Because there is a risk of dependency associated with taking phentermine, it is considered a controlled substance. It is chemically similar to the stimulant amphetamine, which is also a controlled substance (3). A healthcare professional may prescribe phentermine if you have obesity, defined by a body mass index (BMI) of 30 or higher. Health care professionals may also prescribe it if you’re overweight with a BMI of at least 27 and have at least one weight-related condition, such as high blood pressure, high cholesterol, or type 2 diabetes (4, 5). However, a doctor will likely recommend other weight loss strategies first, such as: B. Exercise and a calorie-restricted diet. Summary Phentermine is an FDA approved weight loss drug. Its chemical structure is similar to that of the stimulant amphetamine and is only available by prescription.

How does it work? Phentermine belongs to a class of drugs called appetite suppressants, also known as appetite suppressants. Taking phentermine helps suppress your appetite, which limits the number of calories you eat. Over time, this can lead to weight loss. While the exact way phentermine reduces appetite remains unclear, the drug is believed to work by increasing neurotransmitter levels in your brain (6, 7). Neurotransmitters — the chemicals norepinephrine, serotonin, and dopamine — are your body’s chemical messengers (6, 7). As your levels of these three chemicals increase, your feeling of hunger decreases. However, you can build up a tolerance to the appetite suppressant effects of phentermine within a few weeks. In this case, talk to the doctor who prescribed it. Summary Phentermine is thought to decrease your appetite by increasing neurotransmitter levels in your brain.

What is it used for? Phentermine is most commonly used for weight loss, but it can also be used in combination with the drug topiramate to help with certain eating disorders, such as binge eating disorder (BED) (8). Effective for Weight Loss Several clinical studies have shown that phentermine can support meaningful weight loss. Although the FDA has only approved it for short-term use of less than 12 weeks, healthcare professionals often prescribe phentermine off-label for longer-term use. Doctors can prescribe it intermittently, meaning you pause the drug for a period of time before restarting it (5, 9). The average weight loss when taking phentermine is 3% of your original body weight at 3 months and 5-7% at 6 months. Some people report even more weight loss (5, 6, 9, 10). To put this in perspective, a 5-7% weight loss equates to 10-14 pounds (4.5-6.4 kg) for a person who weighs 200 pounds (90.7 kg). However, not everyone responds the same way to this drug. If you haven’t lost much weight after 3 months of use, a doctor may recommend that you stop using the drug. In addition, its effectiveness appears to gradually decrease after prolonged use of more than a year (5, 6, 9, 10). While phentermine has been shown to be effective for weight loss, it may work better when combined with topiramate. Topiramate is a drug that has been used alone to treat seizures, but like phentermine, it also has appetite-suppressing properties (6, 11, 12). Topiramate and phentermine is a combination drug sold under the brand name Qsymia. The FDA approved it in 2012 as an adjunct to healthy lifestyle habits such as increased exercise and a calorie-restricted diet. Compared to three other commonly prescribed weight-loss drugs, the combination of phentermine and topiramate was associated with the highest odds of losing at least 5% of initial body weight (13). In addition, a recent analysis of studies found that people taking a drug that combined phentermine and topiramate lost an average of 7.3 kg compared to a placebo. For those who took the drug for more than 56 weeks, that number rose to 17.8 pounds (8 kg) (14). In addition, the degree of weight loss increased with dose. The average weight loss was (14): 7.8 pounds (3.55 kg) for a 3.75/23 mg dose (phentermine/topiramate).

16 pounds (7.27 kg) for a 7.5/46 mg dose

18 pounds (8.25 kg) for a 15/92 mg dose 16). May Help With Certain Eating Disorders The combination of phentermine and topiramate may help reduce binge eating in people with BED and bulimia nervosa. BES is characterized by eating large amounts of food, often quickly and to the point of discomfort. It’s also associated with a feeling of loss of control during the binge and feelings of shame or guilt afterwards (17). Bulimia nervosa involves the same binge eating behaviors as BED, but also includes behaviors that people engage in to offset the effects of binge eating, such as binge eating. B. Self-induced vomiting (17). In a small 12-week study of people with BED who were overweight, people taking a drug combination of phentermine and topiramate experienced a significant reduction in the frequency of binge eating episodes ( 18Trusted Source ). In another 12-week study, people with BED or bulimia nervosa received the drug combination or a placebo (19). Over 28 days, treatment with the combination of phentermine and topiramate reduced the number of binge-eating days in participants from 16.2 to 4.2. The same results were not observed in the placebo group (19). While these results are promising, larger studies are still needed. If you think you have BED, bulimia nervosa, or an eating disorder, it’s important to speak to a doctor. Summary Phentermine when combined with topiramate has been shown to promote significant weight loss and may help reduce the occurrence of binge eating episodes.

Dosage and Forms Phentermine dosages vary depending on the form and concentration. Phentermine Prior to 2016, the only doses of phentermine available were 15, 30, and 37.5 mg (7, 9). However, because it’s good practice for physicians to prescribe the lowest effective dose, in 2016 the FDA approved an 8 mg formulation (Lomaira) that can be taken at least 30 minutes before meals, up to three times a day. If you are prescribed a higher dose (15, 30 or 37.5 mg) you can take it once a day in the morning before breakfast or 1-2 hours after breakfast. To prevent insomnia or problems falling asleep or staying asleep, you should not take the last dose too late in the day. Phentermine and Topiramate The combination of phentermine and topiramate – sold under the brand name Qsymia – is a weight loss drug. This drug is available in four doses with strengths ranging from 3.75-15 mg phentermine and 23-92 mg topiramate. It comes in an extended-release capsule that should be taken in the morning (7, 9, 20). After you’ve been on the lowest dose for 14 days, your doctor may decide to switch you to a higher dose (9, 20). According to the FDA, if you don’t lose 3% of your body weight after 12 weeks at the highest daily dose, you should stop taking the drug (20). Summary The dosage of phentermine differs depending on whether it is used alone or together with topiramate.

Side Effects and Precautions Phentermine alone is for short term use only as there are few long term studies on its safety. One study observed that people did not experience any significant side effects when taking phentermine for up to 24 months (10). However, the FDA has approved phentermine for long-term use in combination with topiramate because the doses of the two ingredients are lower than the maximum doses of the individual drugs (20). The most commonly reported side effects of phentermine and combined phentermine and topiramate are (6, 20, 21): Dry mouth

sleep disturbance

dizziness

palpitations

skin redness

fatigue

constipation

irritability

nausea

Vomiting Although rare, some serious side effects are possible, such as B. increased blood pressure, suicidal ideation, metabolic acidosis, increased creatinine levels, fetal harm, visual disturbances, cognitive impairment and hypokalemia (6, 20, 21). You shouldn’t take phentermine if you have heart disease, hyperthyroidism, glaucoma, or severe kidney or liver disease, or if you’re pregnant or breastfeeding (6, 20, 21, 22). Phentermine should also not be prescribed in combination with monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression. Talk to a doctor if you’re taking other medications, like antihypertensive or antiepileptic drugs (20). Your doctor will determine if phentermine is appropriate and safe for you. Summary While some common side effects are associated with phentermine and topiramate use, most people tolerate it. However, individuals who have certain medical conditions or who are pregnant or breastfeeding should not use phentermine and topiramate.

Healthy Ways to Promote and Maintain Weight Loss Most often, medical professionals prescribe phentermine and topiramate after trying other lifestyle changes for weight loss but not seeing significant results. While phentermine can be a powerful weight-loss aid, the only proven way to lose weight and maintain it long-term is through a healthy lifestyle (23, 24). Without these habit changes, you may regain the weight you lost—and potentially more—once you stop taking phentermine (25). Instead, it’s best to prioritize healthy, sustainable lifestyle choices that promote health beyond weight loss. Extensive research has shown that exercise, a nutritious diet, stress management, and proper sleep are critical to promoting better health and reducing your risk of disease (26, 27, 28, 29). Additionally, taking medication long-term is not without its risks, and the costs can add up, especially if you don’t have insurance. For these reasons, a doctor will likely recommend that you make healthy lifestyle changes before recommending any weight loss medication. Some examples of healthy lifestyle changes you can make are (23, 24, 30): Eating a calorie-restricted diet. If you want to lose excess weight, you can try to cut down on 300-500 calories per day. A Registered Dietitian can help tailor this range to suit your preferences and goals.

If you want to lose excess weight, you can try to cut down on 300-500 calories per day. A Registered Dietitian can help tailor this range to suit your preferences and goals. Favor nutrient-rich foods. Nutrient-dense foods like fruits and vegetables are relatively low in calories and high in nutrients like fiber, vitamins, and minerals.

Nutrient-dense foods like fruits and vegetables are relatively low in calories and high in nutrients like fiber, vitamins, and minerals. increase in physical activity. The US Department of Health and Human Services recommends at least 150 minutes of moderate aerobic exercise, such as brisk walking or running, per week.

The US Department of Health and Human Services recommends at least 150 minutes of moderate aerobic exercise, such as brisk walking or running, per week. Sleep more. Although individual needs vary, aim to get 7-9 hours of sleep per night.

Although individual needs vary, aim to get 7-9 hours of sleep per night. Do your best to manage your stress levels. Managing stress can help reduce emotional eating and inflammation. You can try strategies such as medication, walking, socializing with friends and family, or talking to a trained professional.

Managing stress can help reduce emotional eating and inflammation. You can try strategies such as medication, walking, socializing with friends and family, or talking to a trained professional. try behavioral strategies. Behavior changes that may help include self-monitoring of your food intake, physical activity, and weight, and making adjustments as needed. These lifestyle changes can be difficult, and you don’t have to make them all at once. Instead, slowly incorporate new healthy behaviors over time. This will help promote long-term, sustainable results. Summary Lifestyle and behavior changes are the cornerstones of successful weight loss and weight maintenance.

Adipex (Phentermine) is a prescription drug that helps people with weight loss. It works by reducing appetite and is usually prescribed for three to six weeks (although it can be used for up to 12 weeks) for people who exercise and eat a low-calorie diet.

Phentermine is also the active ingredient in other prescription drugs including Fastin, Ionamin and Zantryl and is one of the two ingredients in Qsymia. These drugs are the most commonly prescribed diet pills on the market. Because these drugs are similar to amphetamines and act as a stimulant, they are a controlled substance and are often sold illegally.

Knowing how phentermine works in your system and for how long can help you avoid drug interactions and side effects. It is also important to note that phentermine has the potential to be addictive.

Adipex can be detected in blood, urine and hair. The SAMHSA amphetamine test on the 5-panel urine test is the most commonly performed test. Hair follicle tests and blood tests are less common but can also be used.

Very good / Gary Ferster

How long does it take to feel the effects?

Phentermine works similarly to amphetamines by suppressing appetite, stimulating the central nervous system and increasing blood pressure. Phentermine is absorbed from the gastrointestinal tract and reaches peak blood levels within three to 4.4 hours. At this point you should start to feel the effects, which will let you know that the drug is working.

Short-term effects of Adipex may include:

Decreased appetite

euphoria

hyperactivity

anxiety, irritability

chest pain

It is taken either as a prolonged-release capsule, which is taken once a day in the morning, or as a tablet, which is taken three times a day half an hour before meals.

Phentermine increases norepinephrine, dopamine, and serotonin levels and produces effects similar to amphetamine. Because of this, phentermine is a controlled substance and is only legally available through a prescription.

How long does Adipex last?

Adipex has a half-life of about 20 hours, which is the time it takes for half of the dose to be metabolized by the liver or excreted unchanged in the urine. It takes five to six half-lives for Adipex to be completely eliminated from your system.

A typical dose of Adipex is one 37.5 mg capsule in the morning before breakfast. Adipex capsules contain the active ingredient phentermine hydrochloride, 70% to 80% of which is excreted unchanged in the urine. The rest undergoes N-oxidation and N-hydroxylation to form corresponding metabolites.

blood

Adipex is detected via a blood test for up to 24 hours.

urine

Adipex is detected by the SAMSHA 5 panel amphetamine test for one to four days. Urine tests are the most common, so it’s fairly safe to stop taking Adipex a week before the drug test and expect it not to show up on the test.

hair

The hair follicle drug test can detect Adipex for several months.

False positive tests

Because phentermine is similar in structure to amphetamines, it can give a false positive in urine drug tests for amphetamines or MDMA, a 2016 study confirms. A positive result signals the need for a confirmatory test, which then shows that it is was phentermine and not amphetamine or methamphetamine. The original result is then considered a false positive.

If you have a prescription for phentermine, you should let the testing lab know so that your results can be properly interpreted.

Factors affecting detection time

The amount of phentermine that tests detect and how long it stays in your system depends on a number of factors.

Age

The metabolism of Adipex may take longer in older people.

dosage

Taking more than the recommended dose and using it off-label can allow Adipex to stay in your system longer.

metabolism

A person of average build and metabolism can expect phentermine to be present in their urine for three to five days. It may take longer for older people

How to get Adipex out of your system

It is recommended to taper off the use of Adipex rather than stop immediately. Adipex is generally cleared from your system about two days after you last took it.

Phentermine is stored in body fat and fat burning can aid in elimination. However, there is no healthy way to speed up this process. If you expect to be tested for Adipex, state that you are taking it or stop using it before being tested. People who are prescribed Adipex for weight loss often expect to take it for several weeks. plan ahead.

Remember that showing up for a drug test is no problem for Adipex if you take the drug as prescribed by your doctor.

Symptoms of an overdose

Phentermine has stimulant properties and can affect neurotransmitters such as dopamine, norepinephrine, and serotonin. This is very similar to amphetamines. For this reason, prescriptions are strictly regulated and often only permitted for short periods of time. It is not recommended for people with a history of stimulant use disorder.

Some of the serious side effects of Adipex include increased blood pressure, palpitations, restlessness, dizziness, tremors, insomnia, shortness of breath, chest pain, and swelling of the legs and ankles.

Symptoms of an Adipex overdose, on the other hand, may include:

confusion

panic

hallucinations

Extreme restlessness

nausea

Vomit

Diarrhea

Stomach cramps

tiredness or depression

Irregular heartbeats

Weak pulse

seizure

Slow breathing (breathing may stop)

If you think someone has overdosed on phentermine medication, call the Poison Control Center at 1-800-222-1222. If the victim has collapsed or is not breathing, call 911 immediately.

Interactions with other drugs

It’s important to discuss all your medications and supplements with your doctor to avoid drug interactions. Drugs of particular concern include those used to treat depression and related disorders, including:

Monoamine oxidase inhibitors (MAOIs) such as Marplan (isocarboxazid) and Nardil (phenelzine)

Selective serotonin reuptake inhibitors (SSRIs) such as Prozac (fluoxetine), Luvox (fluvoxamine), Paxil (paroxetine), and Zoloft (sertraline)

Your doctor should also be made aware of any history of heart disease, including high blood pressure and atherosclerosis, or an overactive thyroid. It’s also best to avoid alcohol while taking Adipex, as the combination can increase the effects.

get help

Withdrawal symptoms from Adipex tend to peak within the first few days and decrease over the next week. Common withdrawal symptoms from Adipex include:

headache

lack of energy

High blood pressure

Diarrhea

stomach pain

Vomit

menstrual irregularities

insomnia

irritability

memory loss

palpitations

If you regularly take Adipex in high doses and stop taking it too soon, you could be at risk of more serious problems, including:

heart failure

cardiac arrest

dashes

Tremble

seizures

nerve damage

Adipex and other phentermine-containing medications may be available by prescription and can help you with your weight loss goals. However, it’s important to recognize that there are potential risks involved, including developing addiction and even stimulant use disorder.

You may find it difficult to concentrate without taking Adipex. You could get into unhealthy cycles of taking more and less of the drug, putting a dangerous strain on your cardiovascular system.

Cravings for Adipex interfering with your daily routine is a reason to speak to a psychologist. Counseling or group therapy can help you understand why you are using Adipex and develop alternatives and strategies to gradually stop using it. Both harm reduction psychotherapy and abstinence-based programs are available, depending on what works best for you.

Water: The first rule of any diet is to drink plenty of water. When you are taking phentermine you should drink at least 8 glasses of water per day to improve your body functions and aid in water weight shed as well as keep you hydrated and less likely to misinterpret thirst for hunger. Chilled water tastes better and is easier for the body to digest, or if you want something warming, green tea is similarly hydrating and counts towards your daily requirement.

Protein: When dieting, it is important that you eat enough protein. One reason is that high-protein foods take more work to digest, metabolize, and utilize, which means you burn more calories as you process them. They also take longer to leave your stomach, making you feel full sooner and longer. Protein is doubly important when you’re exercising and dieting to ensure you’re losing fat and not muscle. Your body uses protein to build lean muscle, which not only makes you stronger and more toned, but also burns calories even when you’re not active, as opposed to lazy fat, meaning your metabolism works at a faster rate. Good sources of protein include skinless chicken and turkey, tofu, fish, low-fat dairy, lean beef, eggs, and nuts.

Fiber: While fiber isn’t a magic weapon for weight loss, healthy high-fiber foods keep you feeling full so you can resist eating more food than you need. Although phentermine helps suppress your appetite, opting for high-fiber foods means your appetite will be satiated with fewer calories and fat when you are hungry. Good sources of fiber include beans, whole grains and brown rice, nuts, baked potatoes (but you have to eat the skin), berries, bran cereals, and vegetables.

Fruits and Vegetables: The water and fiber in fruits and vegetables add bulk to your meals, allowing you to eat the same amount of food with fewer calories. Most fruits and vegetables fill you up and are naturally low in fat and calories. Choose whole fruits over juices to maximize fiber content, and always make sure your veggies are healthily cooked and served with healthy dressings.

Alkalizing Foods: To maximize the effects of phentermine, an alkaline urine pH (7.5 to 8.0) is required as this means that the phentermine will be eliminated from your body more slowly. Almost all fruits and vegetables are alkalizing so they will help you maintain alkaline levels in your body and therefore you will not experience the effects of phentermine such as phentermine. B. Feeling higher energy levels and a suppressed appetite, longer throughout the day. Other alkalizing foods are almonds, chestnuts, tofu, stevia, cinnamon, curry, ginger, mustard, chili and all herbs.

What to avoid

Simple Carbohydrates: Foods that contain simple carbohydrates include table sugar, products made with white flour, candy, chocolate, cake, jam, cookies, soda, and packaged cereal. They are digested quickly by your body, causing dramatic changes in your blood sugar levels, and are not used by your body for fuel, often being stored as fat. When you include carbohydrates in your diet, you make them complex carbohydrates; these take longer to digest and are packed with fiber, vitamins and minerals. Examples include vegetables, whole wheat bread, oatmeal, legumes, brown rice, and whole wheat pasta.

Sugar: Added sugar provides a lot of fructose that can only be processed by the liver. When the liver is already processing food, the extra sugar is stored as fat. Sugar directly increases your chances of becoming obese due to increased insulin resistance, as well as a rise in cholesterol and your chances of developing diabetes. Sugar is found in many of the simple carbohydrates listed above and hidden in many processed foods like frozen foods. Dried fruit and store-bought fruit juices can also be high in sugar, so fresh fruit and freshly squeezed juices are preferable.

Alcohol: Like high sugar levels, alcohol can affect your liver functions by inhibiting your body’s fat-burning systems for several days, allowing the liver to burn less fat.

Acidifying Foods: In addition to being bad for weight gain and inhibiting fat burning, the above foods are also acidifying, meaning these foods are especially important for those taking phentermine. The reason for this is that acidifying foods increase the elimination of phentermine, which means it doesn’t last in your system as long as it should. So stay away from soda, alcohol, coffee, sugar, butter, ice cream and products that contain white flour.

While taking phentermine, it’s important to get used to eating the right foods so you can re-educate your mind to provide your body with the best. When you reach your goal weight, it’s the changes you make on your weight loss journey that will help you maintain your new body. All in all, the odd treat here and there means you don’t feel disadvantaged and end up undoing all your good work along the way.

Are you a patient seeking obesity treatment? Find an obesity medicine specialist who can assist you with your health and weight loss goals. Click here to find an obesity medicine doctor near you.

Weight loss medications are an important part of a complete treatment plan for obese (BMI > 30) or overweight (BMI > 27) adults with increased obesity-related complications. The benefits of weight loss medication include: appetite control, improvement in eating habits, and slowing the progression of weight gain and regain.

Prior to 2012, there were few weight loss drugs approved by the U.S. Food and Drug Administration (FDA). The top drugs back then were phentermine and orlistat.

Currently available weight loss drugs

Phentermine (Adipex, Ionamin, Suprenza) and diethylpropion are the oldest weight loss drugs. Phentermine is available in daily doses of 37.5 mg, 30 mg, 15 mg, and 8 mg (Lomaira). Approved by the FDA for short-term use, Phentermine is an adrenergic agonist that suppresses appetite. Side effects include: dry mouth, insomnia, dizziness, and irritability. Caution should be exercised in patients with hypertension.

Orlistat is a weight loss pill that inhibits lipase in the pancreas and stomach, reducing fat absorption in the gastrointestinal tract. It is available for mealtime use in doses of 120 mg (Xenical) and 60 mg (Alli) OTC. Side effects are: Flatulence with discharge of fat and urge to defecate after eating high-fat food, side effects that lead to discontinuation of the medication.

Since 2012, the FDA has approved four safe weight loss drugs for long-term weight management.

Phentermine-Topiramate Extended Release (Qsymia) is the most effective weight loss drug to date. It combines an adrenergic agonist with a neurostabilizer. Four strength daily doses start at 3.75/23 mg to 15 mg/92 mg. Adults with migraines and obesity are good candidates for this weight loss drug. Side effects include: abnormal sensations, dizziness, changes in taste, insomnia, constipation, and dry mouth. Contraindications include: uncontrolled hypertension and coronary artery disease, hyperthyroidism, glaucoma and sensitivity to stimulants. If weight loss of more than 5% is not achieved after 12 weeks of the maximum dose, the weight loss pill should be discontinued gradually.

Bupropion/naltrexone (Contrave) combines a dopamine/norepinephrine reuptake inhibitor and an opioid receptor antagonist. Start with a daily dose of 8/90mg tablet up to four tablets per day. It controls food cravings and addictive behaviors. Side effects include: constipation, headache, insomnia and dry mouth. Contraindications include: uncontrolled hypertension, history of seizures, and opioid use and addiction.

Liraglutide (Saxenda) is a glucagon-like peptide 1 (GLP-1) receptor approved as Victoza for type 2 diabetes and as Saxenda for weight loss injections. Dosing starts at 0.6 mg to 3 mg per day. Liraglutide delays gastric emptying and causes a feeling of satiety. Good candidates are adults with diabetes and prediabetes. Side effects include: nausea, vomiting, diarrhea, constipation and abdominal pain. It is contraindicated in patients with a personal or family history of medullary thyroid carcinoma.

Obesity drugs are for long-term use because obesity is a chronic disease. They improve health, quality of life and body weight in overweight and obese patients.

Weight loss medications are just one component of a comprehensive treatment plan that also includes diet, exercise, and behavioral therapies.

frequently asked Questions

DISCLAIMER:

The following FAQs are for educational purposes only and are in no way intended or should be construed as medical advice. Anyone wishing to begin a new diet, physical activity, or medication should always consult their primary care physician first to learn how participation may affect or limit certain health conditions. This list of frequently asked questions and answers about phentermine was prepared by A Better Way Health Center Medical Director, Richard A. Nelson, M.D. dr Nelson is a graduate of University Medical School and a former staff fellow and visiting researcher at the National Institutes of Health (NIH). The following information is provided as a courtesy and not as medical advice based on his review of the phentermine related literature and his nine year experience with approximately eight thousand patients in over forty thousand doctor visits.

How exactly does phentermine work? The full mechanism of action of Phentermine has not been definitively defined. However, it is currently believed to have its primary effect on the hypothalamus, which is a very deep part of the brain responsible for hunger and thirst, affecting levels of arousal and sleep. By affecting neurotransmitter reuptake in this area of ​​the brain, phentermine effectively reduces appetite to levels below normal levels. A significantly reduced appetite makes a calorie-restricted diet much easier to follow, which aids in the weight loss process.

Is phentermine the same as fen-phen?

Phentermine was half of Fen-Phen. Fen-phenâ was a nickname for the combination of fenfluramine and phentermine for weight loss, which was widely used from about 1994 to 1997 in the US market by their manufacturers at the request of the Food and Drug Administration (FDA) due to concerns that these drugs were being used by some Users of these drugs could possibly damage the heart valves. It was determined that phentermine used without fenfluramine is not associated with this increased frequency of heart valve changes and was therefore allowed to remain on the US market as it has been for the past 40 years.

Is Phentermine sold under other names? Phentermine is the name of the generic drug. Phentermine trade names include: Adipex, Ionomin, and Fastin.

Does phentermine have ephedrine in it?

no Phentermine and ephedrine are two different drugs. Phentermine is only available by prescription and is not sold as part of an herbal cocktail, while because ephedrine is naturally occurring and not under as strict FDA scrutiny, ephedrine has been used in a variety of herbal energy boosters, fat burners, and diet supplements. Given the recent tragic events surrounding ephedrine-containing products, that could soon change. no Phentermine and ephedrine are two different drugs. Phentermine is only available by prescription and is not sold as part of an herbal cocktail, while because ephedrine is naturally occurring and not under as strict FDA scrutiny, ephedrine has been used in a variety of herbal energy boosters, fat burners, and diet supplements. Given the recent tragic events surrounding ephedrine-containing products, that could soon change.

Is Phentermine Addictive?

Phentermine is classified by the Food and Drug Administration (FDA) as a Schedule 4 controlled substance, meaning it has minimal liability for abuse. (Table 1 is the highest and 5 is the lowest) Tolerance to the drug evolves as its side effects and some of its appetite suppressant effects diminish over time, a common component of a potentially addictive drug. However, the vast majority of participants do not experience a significant euphoric effect or high from the drug, nor does development of craving for the drug appear to occur. If the drug were stopped abruptly, many participants would experience some rebound hunger and some rebound fatigue, but not the severe withdrawal symptoms commonly associated with abrupt nicotine or caffeine withdrawal. So while the possibility of Phentermine addiction needs to be kept in mind, based on our experience it appears to be a very rare occurrence. The development of a psychological dependence on phentermine, where participants use the drug rather than developing good health habits, rather than as an adjunct to this process, is probably of more interest. This is something we pay attention to to help participants not view phentermine as some kind of crutch and is the main reason why we do not recommend the use of phentermine for those who are only aiming for modest weight loss.

What are the side effects of phentermine? Dry mouth is the most common side effect we see and the one that lasts the longest. It’s usually manageable by following sensible measures like drinking plenty of water and chewing sugar-free gum.

Insomnia is the second most common side effect, which takes the form of either difficulty falling asleep or waking up very early in the morning and not being able to get back to sleep. This occurs mainly in the first week of phentermine use, which recedes to an annoyance level; However, in some patients it may last for a few weeks and gradually decrease over time. Constipation is also fairly common and persistent for some, but except in rare cases it can usually be treated with aggressive water and fiber intake. Mild headaches, restlessness, anxiety, irritability, and occasional heart palpitations are not uncommon in the first few days of a new user starting Phentermine, but usually subside quickly during the first week.

Other side effects are rare and usually mild when they occur and include: dizziness with sudden standing, blurred vision, hesitancy to urinate (in men) and occasional gastrointestinal upset when taken on an empty stomach. Below our program results, we list the percentage of participants (of the first 500 at visit 5) who report symptoms thought to be likely related or related to the use of phentermine. At Visit 4, approximately six weeks into the program, the only side effect that persisted in more than 10 percent of the participants was dry mouth, and the only symptoms that persisted in more than 2 percent of the participants were: dry mouth, insomnia, and Constipation. As tolerance to phentermine continues to build, these effects gradually wear off.

If tolerance to the effects of phentermine develops, does phentermine stop working after some time? As tolerance to side effects builds, most participants will also experience the development of tolerance to the appetite suppressant effects of phentermine over time. This tolerance development can be largely compensated for by gradually up-titrating the drug dose, usually adding a second dose in the early afternoon to continue to provide good all-day appetite control. Since too early or inappropriate titration of the dose can provoke the recurrence of unpleasant side effects, this dose titration should only be performed under medical supervision.

When looking for a new diet, physical activity, or medication, you should always consult your primary care physician first.

On days when I forgot to take phentermine, I still don’t feel hungry. Why is that? Phentermine takes about three to five days to build up in the system (to what is known as a steady state), which is why some people report not feeling its full effects until after taking it for several days.

Similarly, phentermine also takes about three to five days to be flushed out of the blood, so if a day is missed, quite a bit still remains in the system. While forgetting one day seems to have little effect here or there, we still found that the participants who performed best at weight loss were those who took their prescribed doses of phentermine very regularly every day.

Do you recommend buying Phentermine over the internet? If you buy Phentermine from a reputable US source like Walgreens.com that requires a prescription from your doctor, you can probably rest assured that you are getting a legitimate product. On the other hand, if you are ordering a product from a location with no visible address or an address abroad, and/or one that is dispensing phentermine based on an online doctor’s consultation, aside from the legal issues, you can be at a very real risk accept that the product you receive is not the original. We spoke to several participants at our clinic who reported side effects of phentermine from the internet, leading us to believe that what they were receiving was not phentermine. So be very careful.

What is the average weight loss I should expect to lose in the program? Because our program is designed to develop long-term healthy behavior and not acute dramatic weight loss, we advise patients who adhere to the program to expect an average weight loss of one and a half to two pounds per week, or about one percent of her Body weight per week, which is considered optimal to maintain muscle mass while burning fat. With this plan, the transition to the weight maintenance phase of the program is then a very smooth process, in which diet and exercise habits remain the same as in the weight loss phase, while calorie intake is gradually increased to support the new weight.

Can I take Phentermine if I am also taking an antidepressant? Phentermine is a prescription drug approved by the US Food and Drug Administration (FDA). This is a question that is best answered by your GP or psychiatrist.

There is a class of older antidepressants called MAOIs that you definitely cannot take in combination with phentermine. We are not aware of any adverse interactions in patients on the newer antidepressants that are more commonly used (e.g. Prozac, Paxil, Zoloft, Celexa, Effexor) and we have many patients in the program who are on any of these drugs and are doing it well, but your doctor should still be consulted.

Can I use Phentermine if I’m pregnant or breastfeeding? Although phentermine has not been linked to birth defects in any animal studies, we do not recommend its use by women who are pregnant or planning to become pregnant. Since phentermine can be found in breast milk, we also advise against using phentermine by breastfeeding women.

What over-the-counter medications should I avoid when taking Phentermine? For those taking phentermine, we advise caution when using other over-the-counter stimulants, particularly the decongestants (pseudoephedrine) and caffeine. If a decongestant must be used, we recommend that a participant have their blood pressure checked multiple times while taking this product. We also recommend avoiding any products that contain the drug ephedrine. This long list includes various energy boosters, fat burners and various dietary supplements that promise metabolism-stimulating effects.

How often and when should I take Phentermine? To begin with, one intake per day is usually sufficient for good all-day hunger control. We usually recommend taking Phentermine around 9 or 10am so that it will be effective until lunchtime, last until dinnertime and still wear off by bedtime for sleep.

What Dose of Phentermine Do You Prescribe? Unless otherwise indicated by the participant’s medical history, a single 30 milligram pill taken once daily is our usual starting dose. On return visits, this dose may need to be increased (if hunger persists) or decreased (if side effects persist) depending on the participant’s response. Matching the dose to the patient is an art of sorts, and having seen several thousand patients using this drug helps.

Do I need to worry about being on phentermine if I get drug tested? There are some professions such as B. Commercial airline pilots where the use of phentermine (along with many medications) is not permitted. In all other cases, to the best of our knowledge, a letter from our program stating that a participant is receiving this medication as part of a physician-supervised weight loss program is sufficient to avoid problems. Because of its similar chemical structure, phentermine could cause a false-positive result for amphetamine-like drugs in a wide-screen immunoassay, such as B. a urine tox screen generate. A more specific follow-up test, such as A gas chromatography, for example, should then clarify that the drug is phentermine and not an illegal substance. However, showing our letter to an employer before a drug test has been carried out should prevent this from becoming a problem.

Is there any way to tell how I will react to phentermine other than by trying it? A very rough indicator would be examining how you respond to other stimulant medications such as caffeine and over-the-counter decongestants. If you are extremely sensitive to these products, you may only need a very small dose of phentermine for it to be effective, and a standard starting dose may be too much to produce side effects such as insomnia, nervousness, and tachycardia. On the other hand, if you are very tolerant to stimulants, you may still feel hungry with a standard dose of phentermine, and it may need to be increased to achieve adequate hunger control. Another rough indicator is examining how close blood relatives (i.e. brother, sister) have responded to phentermine, as in our experience close relatives often appear to be quite similar in terms of tolerability.

However, these are only very rough guidelines, and the only definitive test of how you will respond is to actually try it under medical supervision. (Interestingly, initial height does not appear to be a large predictor of initial response to phentermine, with some relatively tall individuals responding to small doses of phentermine and vice versa.)

Can I use Phentermine if I have high blood pressure? History of hypertension is not a precluding condition for the use of Phentermine; However, blood pressure must be adequately controlled prior to beginning the program (e.g., ideally systolic blood pressure < 135 mmHg and diastolic blood pressure < 85 mmHg). We measure blood pressure at each visit and refer patients back to their GP for more appropriate blood pressure monitoring before continuing the program if it becomes too high. However, as our results show, the average blood pressure among program participants actually decreases from the first visit, and the number of patients who actually experience an increase in blood pressure over the course of the program is quite small.

You should not use phentermine if you are allergic to it or if you:

a history of heart disease (coronary artery disease, cardiac arrhythmias, congestive heart failure, stroke);

severe or uncontrolled high blood pressure;

hyperthyroidism;

Glaucoma;

extreme excitement or nervousness;

a history of substance abuse; or

if you are taking other diet pills.

Do not use phentermine if you have used an MAOI in the past 14 days. It can lead to a dangerous interaction with other medicines. MAOIs include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use phentermine if you are pregnant. Tell your doctor immediately if you become pregnant during treatment.

You should not breast-feed while using phentermine.

Tell your doctor if you have ever had:

heart disease or coronary artery disease;

a heart valve disease;

high blood pressure;

diabetes (your diabetes medication dose may need to be adjusted); or

kidney disease.

Phentermine is not approved for anyone under the age of 16.

Phentermine is a popular weight loss drug that helps suppress appetite. No recipe can replace a healthy diet and exercise. However, drugs like phentermine can help those who are struggling to lose weight through diet and exercise alone. Phentermine can enhance weight loss in some people, although results may vary from person to person. It depends on their reaction, how long they use it and their weight loss activities. Some people should not take phentermine for weight loss. For them, the risks outweigh the potential benefits. In this article, we look at what the current research says about phentermine, whether it helps with weight loss, recommended dosages, and how to use it.

Definition Share on Pinterest A person should discuss weight loss options with their doctor. Phentermine is a short-term weight loss drug approved by the Food and Drug Administration (FDA). The National Library of Medicine advises that people should only use the drug for a few weeks. Phentermine stimulates certain brain chemicals that tell the body it’s full. This can curb appetite sooner and help a person eat less. It is a complementary therapy for people who find it difficult to lose weight after making diet and lifestyle changes to maintain a moderate weight.

It works? In many cases, phentermine helps with weight loss. Since its approval in 1959, it has remained one of the most popular prescription weight loss drugs, either alone or as part of a combination therapy. The exact mechanism of how phentermine helps suppress appetite is unclear. Researchers suggest the drug increases neurotransmitter levels in the brain, which reduces hunger. Weight loss results can also depend on the person’s general changes in their diet and lifestyle. These include regular exercise, calorie restriction, and a healthy diet. These changes alone are often enough to induce weight loss, although phentermine can enhance these effects. For example, a study in Obesity notes that phentermine can increase the efforts of some diet programs. This study finds that people who replaced one meal a day to reduce their calorie intake lost weight. And those who added phentermine to their program lost more weight and had fewer cravings.

When and how to use Phentermine is for people with obesity or those who are unable to lose weight with a balanced diet and exercise alone. You should have a BMI over 30 or over 27 with a weight-related medical condition. Importantly, a person should still make diet and lifestyle changes to support their weight loss in order for the drug to work properly. Phentermine is not for people looking to lose a few pounds or who are otherwise healthy. Doctors adjust each dose so that a person takes in the lowest effective amount. Phentermine is also a short-term drug. A few studies report on the safety of phentermine for long-term use, but it is still intended for a few weeks of use.

Risks There are risks with phentermine, and a doctor will discuss them before prescribing the weight loss drug. Side Effects Phentermine alone or in combination with other medications such as topiramate may carry its own risk of side effects including: trouble sleeping or staying asleep

chest pain

dizziness

increased blood pressure

constipation

Diarrhea

Vomit

restlessness

palpitations

unpleasant taste

dry mouth

Swelling in the legs and ankles

Shortness of breath In some cases, these drugs can also make someone unable to drive or use heavy machinery. Doctors recommend that people take time off work when first starting the drug to gauge side effects. Other Conditions or Medications A person’s conditions or medications may mean that phentermine is unsuitable for them as a weight loss medication. These include: Hyperthyroidism

glaucoma

a history of cardiovascular disease

a history of drug abuse

Use of antidepressants such as monoamine oxidase inhibitors or selective serotonin reuptake inhibitors. Pregnant or breastfeeding women should also avoid phentermine until they stop breastfeeding. Doctors will monitor people with diabetes or hypoglycemia who are taking phentermine. They may need to reduce their insulin or other medications when taking the drug. Phentermine might also interact with alcohol, so a person taking the drug should try to avoid alcoholic beverages. Risk of Abuse and Tolerance Phentermine is chemically related to amphetamine drugs such as methamphetamine, a stimulant with a history of abuse. Therefore, there is a potential for abuse and addiction when someone is taking phentermine. Some people can become tolerant to the drug and want more to experience the same effects. In these cases, it is important to stop taking phentermine altogether and switch to other methods of weight loss. Individuals taking longer doses may also experience withdrawal symptoms when stopping the drug. In any case, talk to a doctor about the risk of withdrawal. Overdose A person who takes too much phentermine can overdose. Symptoms include: Hyperactivity

rapid breathing

psychosis

confusion

hallucinations

panic attacks

fatigue

depression

nausea

fast heartbeat

high or low blood pressure

cramps

coma

Forms and Recommended Dosage Phentermine, or a drug that contains a mixture of phentermine and other drugs, usually comes in a capsule for oral use. Doctors can adjust the amount to ensure a person is taking the minimum effective dose. Typical doses of phentermine for adults contain 15 milligrams (mg), 30 mg, or 37.5 mg, which provides 12 mg, 24 mg, or 30 mg of phentermine, respectively. A daily dose of phentermine and topiramate can vary from 3.75 mg phentermine and 23 mg topiramate to 15 mg phentermine and 92 mg topiramate. Some underlying conditions also change the dosage recommendations. People with impaired kidney function may need lower doses to avoid putting extra strain on these organs. Others with late-stage kidney disease may not be able to take the drug. Doctors do not recommend phentermine in older adults because it can put a strain on the kidneys. Children under the age of 16 should also avoid the drug due to uncertain risks. It is also not advisable to take the drug in the evening or at night as it can cause insomnia. Different forms and dosages of phentermine vary in price. In some cases, the health insurance company can also help to cover the costs.

Weight Loss Tips Phentermine can help people lose weight, but it’s still a complementary treatment. A healthy diet and lifestyle changes should be the foundation of maintaining a moderate weight. General weight loss tips include: Eating a healthy diet and eating nutrient-dense foods like fruits, vegetables, whole grains, and lean proteins.

Get regular physical activity, including cardio and strength training.

Avoid fatty or less nutrient dense foods like fast food or packaged goods.

Avoid extra calories from sugar-sweetened beverages. Here are some tips on how to lose weight safely and naturally.

We’ve all heard that breakfast is supposed to be the most important meal of the day, but you may be wondering exactly what to eat for breakfast to lose weight with phentermine. Besides boosting energy levels and helping focus, taking the right nutrients in the morning can really help you on your weight loss journey. Breakfast helps you lose weight by boosting your metabolism and stopping cravings for unhealthy mid-morning snacks. Here we tell you everything you need to know to start your day off right to lose weight with phentermine.

The importance of breakfast

Maintaining a good metabolism is an important part of long-term weight loss. Not eating by midday can mean your body is without food for up to 18 hours. Instead of running smoothly and burning calories, your body tries to conserve whatever it can. A healthy breakfast will speed up your metabolism and make your body work more efficiently. So, after first taking your phentermine, fuel up with a healthy breakfast as part of your ideal phentermine weight loss plan. Instead of saving calories, skipping breakfast can actually stall weight loss.

Additionally, those who skip breakfast also have difficulty incorporating key weight-loss nutrients into their diets, since many breakfast foods contain significant amounts of vitamins C and D, calcium, protein, iron, and fiber. One way to get around this is to supplement your nutrient intake with Phen Vites, the only multivitamin specifically formulated to help people lose weight. Phen Vites are packed with all the essential vitamins and minerals you need to stop cravings, boost health and boost metabolism. Phen Vites also helps minimize the side effects of phentermine such as insomnia, fatigue, and mood swings. But even with this vitamin hit, you still need to eat breakfast to lose weight with phentermine.

It seems counterintuitive that eating breakfast can help you lose weight, but it’s true because eating breakfast keeps you from craving unhealthy foods and overeating later in the day. Excessive hunger can lead to a lack of self-control, and distorted satiety signals make it harder to tell when you’re full. Additionally, skipping breakfast can increase your body’s insulin response, which in turn increases fat storage and weight gain. Therefore, skipping breakfast actually increases your risk of obesity, as many studies have shown on those who skip breakfast.

Time-saving breakfast tips

As much as we would all like to have a leisurely breakfast with our families at the kitchen table, this is often not possible in our hectic everyday life. However, many breakfast foods can be prepared quickly, such as muesli, fruit and yogurt or whole wheat toast with nut butter. Even a handful of nuts, a smoothie, or portable fruits like bananas and apples can give us a much-needed boost before heading out to work or school. Another good diet tip is to cook things up for the week on a Sunday night, such as: For example, some boiled eggs for on-the-go snacks or a vegetable frittata to eat over a few days.

Something is better than nothing

Some people really can’t handle morning food and phentermine can sometimes cause a loss of appetite, but everyone should at least try to eat something small – like some skim milk or a healthy homemade smoothie – and then bring along a healthy mid-morning snack, if the hunger comes. If you think you’re doing just fine without breakfast, just try making the switch for a week – you’ll likely notice a difference in your energy levels, mood and focus, not to mention your eating habits throughout the day.

Ideal breakfast food for weight loss with phentermine

The foods you eat for breakfast are very important for weight loss; The right foods can keep you feeling full and energized throughout the morning, while the wrong foods add unnecessary fat and make you dissatisfied when they’re full of empty calories. You should avoid fried foods, sugary cereals, and foods like muffins and croissants that are full of unhealthy trans fats, and opt for a selection of these foods instead:

Fruit is a great breakfast choice as it can help you lose weight by keeping you full with fewer calories. Unprocessed fruits are high in water and fiber, which take up a lot of space in the stomach and leave less room for other foods. Great breakfast options include grapefruit, cantaloupe, and watermelon as their water levels keep you hydrated and full, while raspberries, blueberries, bananas, apples, kiwis, and pears are great sources of fiber that keep you fuller for longer. Enjoy your fruit on its own, in a homemade smoothie or with some low-fat yoghurt.

Yoghurt is a simple but very healthy option for breakfast. Low-fat plain yogurt is high in calcium, which has been shown to help with weight loss, and low-fat Greek yogurt is high in protein, which will fill you up with fewer calories — just make sure the yogurt you choose is unsweetened.

Oats, especially the steel-cut, rolled variety, are packed with fiber, protein, and resilient starches that help you feel full, burn fat, and boost your metabolism. Top them with fruit, nuts and yogurt for a great breakfast full of flavor and texture.

Wholemeal bread is great for its fiber content, which keeps you feeling full for longer. Don’t add empty calories with jam or butter, however, add some almond butter, which has less saturated fat than peanut butter and is high in protein and healthy monounsaturated fats.

Eggs are perfect for mornings as they are high in protein and have been shown to help with weight loss when eaten for breakfast. They’re also very versatile, making a great topping for whole wheat toast when stirred or poached, or cooked for a handy portable breakfast snack.

Muesli is a breakfast staple, but often people don’t know which is the best to choose. The ideal choice is cereal with at least 5 grams of fiber and less than 5 grams of sugar per serving. Topping off your muesli with some skim milk and fruit provides an ideal breakfast combination of filling whole grains, calcium and energizing protein.

Green tea is a great option in the morning since it’s hydrating like water, but the polyphenols and catechins in green tea also give your metabolism a boost. You may prefer coffee, but try to limit your intake as much as possible while using phentermine. Although caffeine is a weight loss booster, coffee has been shown to increase the acidity of your urine pH, which means phentermine will be eliminated from your system sooner. Decaffeinated coffee has the same effect, so it’s the coffee itself that causes this effect, not caffeine. Phentermine should give you the energy boost you need with coffee, but if you feel like you need a little extra help then adding the over-the-counter supplement Phen Caps to your daily routine can help increase the effects of phentermine and yours to increase weight loss results.

A high-protein, high-fiber breakfast is the best way to start the day and is the best option when it comes to losing weight with phentermine. We’d love to know what foods you like to eat for breakfast, or if you have any recipe ideas you’d like to share!

phentermine

Generic Name: Phentermine [FEN-ter-meen]

Brand names: Adipex-P, Lomaira, Suprenza

Drug classes: anorexants, CNS stimulants

Medically verified by Drugs.com. Last updated on May 24, 2022.

What is phentermine?

Phentermine is similar to an amphetamine. It stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Phentermine is used along with diet and exercise to treat obesity, particularly in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Phentermine may also be used for purposes not listed in this medication guide.

warnings

Do not use phentermine if you are pregnant or nursing a baby.

You should not use phentermine if you suffer from glaucoma, hyperthyroidism, severe heart problems, uncontrolled high blood pressure, advanced coronary artery disease, extreme agitation, or a history of substance abuse.

Do not use this medicine if you have used an MAOI such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine in the past 14 days. It can lead to a dangerous interaction with other medicines.

Before taking this medicine

You should not use phentermine if you are allergic to it or if you:

a history of heart disease (coronary artery disease, cardiac arrhythmias, congestive heart failure, stroke);

severe or uncontrolled high blood pressure;

hyperthyroidism;

Glaucoma;

extreme excitement or nervousness;

a history of substance abuse; or

if you are taking other diet pills.

Do not use phentermine if you have used an MAOI in the past 14 days. It can lead to a dangerous interaction with other medicines. MAOIs include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use phentermine if you are pregnant. Tell your doctor immediately if you become pregnant during treatment.

You should not breast-feed while using this medicine.

To make sure this medicine is safe for you, tell your doctor if you have:

heart disease or coronary artery disease;

a heart valve disease;

high blood pressure;

diabetes (your diabetes medication dose may need to be adjusted); or

kidney disease.

Phentermine is not approved for anyone under the age of 16.

How should I take phentermine?

Take phentermine exactly as prescribed by your doctor. Follow all directions on your prescription label and read any medication guides or directions for use. Your doctor may occasionally change your dose.

The doses are usually taken before breakfast or 1 to 2 hours after breakfast. Follow your doctor’s dosage instructions very carefully.

Never use Phentermine in larger amounts or for longer than prescribed. Taking more of this drug does not make it more effective and can cause serious, life-threatening side effects.

This medicine is for short-term use only. The appetite suppressant effect may wear off after a few weeks.

Phentermine can take some getting used to. Abuse can cause addiction, overdose, or death. It is against the law to sell or give away this medicine.

Call your doctor right away if you think this medicine isn’t working as well or if you haven’t lost at least 4 pounds in 4 weeks.

Do not stop using this medicine suddenly, as you may experience uncomfortable withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

dosing information

Usual adult dose for obesity:

8 mg orally 3 times daily 30 minutes before meals OR

15 to 37.5 mg po once a day before breakfast or 1 to 2 hours after breakfast.

Use: Short-term (a few weeks) adjunct to a weight loss regimen based on exercise, behavior modification, and calorie restriction in the management of exogenous obesity in patients with a baseline body mass index (BMI) of 30 kg/m2 or greater, or BMI of 27 kg/m2 or higher in the presence of other risk factors (e.g. controlled hypertension, diabetes, hyperlipidemia).

Usual Pediatric Dose for Obesity:

Age 17 years and older:

8 mg orally 3 times daily 30 minutes before meals OR

15 to 37.5 mg po once a day before breakfast or 1 to 2 hours after breakfast.

Use: Short-term (a few weeks) adjunct to a weight loss regimen based on exercise, behavior modification, and calorie restriction in the management of exogenous obesity in patients with a baseline body mass index (BMI) of 30 kg/m2 or greater, or BMI of 27 kg/m2 or higher in the presence of other risk factors (e.g. controlled hypertension, diabetes, hyperlipidemia).

What happens if I miss a dose?

Take the medicine as soon as possible, but skip the missed dose if it’s late in the day. Do not take two doses at the same time.

What happens if I overdose?

See an ambulance or call the poison control center at 1-800-222-1222. An overdose of phentermine can be fatal.

Overdose symptoms may include confusion, panic, hallucinations, extreme agitation, nausea, vomiting, diarrhea, stomach cramps, tiredness or depression, irregular heartbeat, weak pulse, seizures, or slowed breathing (breathing may stop).

What to avoid

Avoid driving or engaging in hazardous activities until you know how phentermine affects you. Your ability to react may be impaired.

Drinking alcohol with this medicine can cause side effects.

Phentermine Side Effects

Get emergency medical help if you have signs of an allergic reaction to phentermine: hives; difficult breathing; swelling of the face, lips, tongue or throat.

Phentermine can cause serious side effects. Call your doctor at once if you have:

shortness of breath, even with slight exertion;

chest pains, feeling like you might faint;

swelling in your ankles or feet;

pounding heartbeats or fluttering in your chest;

tremors, restlessness, trouble sleeping;

unusual mood or behavior changes; or

increased blood pressure – severe headache, blurred vision, pounding in the neck or ears, anxiety, nosebleeds.

Common side effects of phentermine can include:

Itching;

dizziness, headache;

dry mouth;

unpleasant taste;

Diarrhea;

Constipation;

Stomach pain; or

increased or decreased interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

What other drugs will affect phentermine?

Taking phentermine along with other diet medications like fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung condition called pulmonary hypertension. Do not take phentermine with other diet medications without your doctor’s advice.

Many drugs can interact with phentermine. This includes prescription and over-the-counter medications, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicines you are taking or stopping.

Popular FAQs

Why am I tired of Phentermine? Fatigue or fatigue can occur as a result of sleepless nights or after a period of overstimulation, however, phentermine side effects also include drowsiness, fatigue, and reduced energy levels. If you feel tired or lack energy while taking phentermine and the problem persists, you should consult your doctor as you may be suffering from an undiagnosed medical condition. Is Phentermine Safe to Use? Phentermine is safe to use when taken as directed by your doctor. Make sure your doctor knows about all other medicines you are taking and any medical conditions you have. It should not be taken with other weight loss medications. Although rare, high blood pressure has been reported in some patients. Phentermine should not be taken if: You have cardiovascular disease

you are taking or have recently stopped taking medicines known as monoamine oxidase inhibitors

You have an overactive thyroid

You have glaucoma

You have a history of substance abuse or agitation

You are pregnant or breastfeeding

You are sensitive to or have reacted to other stimulants. How long does it take to lose weight with phentermine? Phentermine should be prescribed as part of a weight loss plan that also includes exercise, behavior modification, and calorie restriction. Phentermine is usually taken for 12 weeks or less. The effects of weight loss depend on the dose of phentermine taken, as well as diet, exercise, and other factors. How long does Phentermine stay in your system? Phentermine stays in your system for about 4 days after ingestion. It takes about 20 hours for half of the drug to leave your body. Many things affect how long it takes for a drug to leave your system. These include your age, diet, kidney and liver function, and other factors. How do I take phentermine for the best results? Take phentermine as directed by your doctor. It is usually taken in the morning before breakfast. It can also be taken 1 to 2 hours after breakfast. Phentermine is not usually taken at night as it can cause insomnia. How does phentermine work? Phentermine affects the neurotransmitters of the brain. It is believed to cause weight loss by suppressing appetite. The exact way phentermine works to cause weight loss is not known. Phentermine belongs to the class of drugs known as sympathomimetic amines. These are commonly known as stimulants. Is Phentermine Approved for Weight Loss? Phentermine is a drug approved for weight loss as part of a program of exercise, calorie restriction, and behavior modification. Phentermine can be prescribed for short-term treatment in people with a body mass index (BMI) of 30 kg/m2 or more. It can also be prescribed to people with a BMI of 27 kg/m2 or more and other risk factors such as high blood pressure, diabetes or high cholesterol. Some of the side effects of phentermine may include: Palpitations

Elevated blood pressure

A sense of unrest

headache

Dry mouth

Diarrhea

constipation

hives

A higher or lower libido

Further information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and only use phentermine for the prescribed indication.

Always check with your doctor to ensure that the information presented on this page is appropriate for your personal circumstances.

Medical Disclaimer

Copyright 1996-2022 Cerner Multum, Inc. Version: 10.01.

Adipex (Phentermine) is a prescription drug that helps people with weight loss. It works by reducing appetite and is usually prescribed for three to six weeks (although it can be used for up to 12 weeks) for people who exercise and eat a low-calorie diet.

Phentermine is also the active ingredient in other prescription drugs including Fastin, Ionamin and Zantryl and is one of the two ingredients in Qsymia. These drugs are the most commonly prescribed diet pills on the market. Because these drugs are similar to amphetamines and act as a stimulant, they are a controlled substance and are often sold illegally.

Knowing how phentermine works in your system and for how long can help you avoid drug interactions and side effects. It is also important to note that phentermine has the potential to be addictive.

Adipex can be detected in blood, urine and hair. The SAMHSA amphetamine test on the 5-panel urine test is the most commonly performed test. Hair follicle tests and blood tests are less common but can also be used.

Very good / Gary Ferster

How long does it take to feel the effects?

Phentermine works similarly to amphetamines by suppressing appetite, stimulating the central nervous system and increasing blood pressure. Phentermine is absorbed from the gastrointestinal tract and reaches peak blood levels within three to 4.4 hours. At this point you should start to feel the effects, which will let you know that the drug is working.

Short-term effects of Adipex may include:

Decreased appetite

euphoria

hyperactivity

anxiety, irritability

chest pain

It is taken either as a prolonged-release capsule, which is taken once a day in the morning, or as a tablet, which is taken three times a day half an hour before meals.

Phentermine increases norepinephrine, dopamine, and serotonin levels and produces effects similar to amphetamine. Because of this, phentermine is a controlled substance and is only legally available through a prescription.

How long does Adipex last?

Adipex has a half-life of about 20 hours, which is the time it takes for half of the dose to be metabolized by the liver or excreted unchanged in the urine. It takes five to six half-lives for Adipex to be completely eliminated from your system.

A typical dose of Adipex is one 37.5 mg capsule in the morning before breakfast. Adipex capsules contain the active ingredient phentermine hydrochloride, 70% to 80% of which is excreted unchanged in the urine. The rest undergoes N-oxidation and N-hydroxylation to form corresponding metabolites.

blood

Adipex is detected via a blood test for up to 24 hours.

urine

Adipex is detected by the SAMSHA 5 panel amphetamine test for one to four days. Urine tests are the most common, so it’s fairly safe to stop taking Adipex a week before the drug test and expect it not to show up on the test.

hair

The hair follicle drug test can detect Adipex for several months.

False positive tests

Because phentermine is similar in structure to amphetamines, it can give a false positive in urine drug tests for amphetamines or MDMA, a 2016 study confirms. A positive result signals the need for a confirmatory test, which then shows that it is was phentermine and not amphetamine or methamphetamine. The original result is then considered a false positive.

If you have a prescription for phentermine, you should let the testing lab know so that your results can be properly interpreted.

Factors affecting detection time

The amount of phentermine that tests detect and how long it stays in your system depends on a number of factors.

Age

The metabolism of Adipex may take longer in older people.

dosage

Taking more than the recommended dose and using it off-label can allow Adipex to stay in your system longer.

metabolism

A person of average build and metabolism can expect phentermine to be present in their urine for three to five days. It may take longer for older people

How to get Adipex out of your system

It is recommended to taper off the use of Adipex rather than stop immediately. Adipex is generally cleared from your system about two days after you last took it.

Phentermine is stored in body fat and fat burning can aid in elimination. However, there is no healthy way to speed up this process. If you expect to be tested for Adipex, state that you are taking it or stop using it before being tested. People who are prescribed Adipex for weight loss often expect to take it for several weeks. plan ahead.

Remember that showing up for a drug test is no problem for Adipex if you take the drug as prescribed by your doctor.

Symptoms of an overdose

Phentermine has stimulant properties and can affect neurotransmitters such as dopamine, norepinephrine, and serotonin. This is very similar to amphetamines. For this reason, prescriptions are strictly regulated and often only permitted for short periods of time. It is not recommended for people with a history of stimulant use disorder.

Some of the serious side effects of Adipex include increased blood pressure, palpitations, restlessness, dizziness, tremors, insomnia, shortness of breath, chest pain, and swelling of the legs and ankles.

Symptoms of an Adipex overdose, on the other hand, may include:

confusion

panic

hallucinations

Extreme restlessness

nausea

Vomit

Diarrhea

Stomach cramps

tiredness or depression

Irregular heartbeats

Weak pulse

seizure

Slow breathing (breathing may stop)

If you think someone has overdosed on phentermine medication, call the Poison Control Center at 1-800-222-1222. If the victim has collapsed or is not breathing, call 911 immediately.

Interactions with other drugs

It’s important to discuss all your medications and supplements with your doctor to avoid drug interactions. Drugs of particular concern include those used to treat depression and related disorders, including:

Monoamine oxidase inhibitors (MAOIs) such as Marplan (isocarboxazid) and Nardil (phenelzine)

Selective serotonin reuptake inhibitors (SSRIs) such as Prozac (fluoxetine), Luvox (fluvoxamine), Paxil (paroxetine), and Zoloft (sertraline)

Your doctor should also be made aware of any history of heart disease, including high blood pressure and atherosclerosis, or an overactive thyroid. It’s also best to avoid alcohol while taking Adipex, as the combination can increase the effects.

get help

Withdrawal symptoms from Adipex tend to peak within the first few days and decrease over the next week. Common withdrawal symptoms from Adipex include:

headache

lack of energy

High blood pressure

Diarrhea

stomach pain

Vomit

menstrual irregularities

insomnia

irritability

memory loss

palpitations

If you regularly take Adipex in high doses and stop taking it too soon, you could be at risk of more serious problems, including:

heart failure

cardiac arrest

dashes

Tremble

seizures

nerve damage

Adipex and other phentermine-containing medications may be available by prescription and can help you with your weight loss goals. However, it’s important to recognize that there are potential risks involved, including developing addiction and even stimulant use disorder.

You may find it difficult to concentrate without taking Adipex. You could get into unhealthy cycles of taking more and less of the drug, putting a dangerous strain on your cardiovascular system.

Cravings for Adipex interfering with your daily routine is a reason to speak to a psychologist. Counseling or group therapy can help you understand why you are using Adipex and develop alternatives and strategies to gradually stop using it. Both harm reduction psychotherapy and abstinence-based programs are available, depending on what works best for you.

Phentermine and topiramate are available as extended-release capsules for oral use. The drug is usually taken once a day in the morning with or without food. This drug can cause trouble falling asleep or staying asleep if taken in the evening. Take phentermine and topiramate at about the same time each day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part that you don’t understand. Take phentermine and topiramate exactly as directed.

Your doctor will likely start you on a low dose of phentermine and topiramate and increase your dose after 14 days. After taking this dose for 12 weeks, your doctor will check how much weight you have lost. If you haven’t lost a certain amount of weight, your doctor may tell you to stop taking phentermine and topiramate, or they may increase your dose and then increase it again after 14 days. After you have taken the new dose for 12 weeks, your doctor will check how much weight you have lost. Unless you have lost a certain amount of weight, it is unlikely that you will benefit from taking phentermine and topiramate, so your doctor will likely tell you to stop taking the drug.

Phentermine and topiramate can be addictive. Do not take a larger dose, more frequently, or for longer than directed by your doctor.

Phentermine and topiramate will only help control your weight as long as you continue to take the drug. Do not stop taking phentermine and topiramate without talking to your doctor. If you suddenly stop taking phentermine and topiramate, seizures may occur. Your doctor will tell you how to gradually reduce your dose.

Phentermine and topiramate are not available in retail pharmacies. This drug is only available through certain mail-order pharmacies. Ask your doctor if you have any questions about how to get your medication.

Your doctor or pharmacist will provide you with the manufacturer’s patient information (medication guide) when you start treatment with phentermine and topiramate and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website for the Medication Guide.

dr Arterburn shares reassuring news from his PCORnet study of the most widely used anti-obesity drug in the United States.

By David Arterburn, MD, MPH, Principal Investigator at Kaiser Permanente Washington Health Research Institute and Physician of Internal Medicine at Washington Permanente Medical Group

Over time, we are realizing more and more how chronic and intractable obesity can be. Comprehensive, intensive interventions to achieve lifelong lifestyle changes—including diet and exercise—are the cornerstones of treatment with long-term follow-up. But such programs don’t work for up to one in three patients. And weight gain is common after 6 months, the point at which such programs can achieve a 5 to 10 percent weight loss.

As placebo-controlled studies have shown, weight-loss drugs are one way to help more people achieve stronger, and potentially longer-lasting, responses to lifestyle interventions. However, these drugs are typically not widely used, mainly due to a lack of insurance coverage, resulting in high patient costs, but also due to concerns about side effects.

Phentermine is the most commonly used anti-obesity drug in the United States. When it was approved for weight loss in 1959, the chronic nature of obesity was not understood. The Food and Drug Administration (FDA) has limited treatment to 12 weeks or less. In contrast, when the FDA approved a new brand-name combination drug, Phentermine/Topiramate-CR (Qsymia), in 2012, it was intended for long-term use for a year or more.

Many doctors prescribe patients phentermine alone for more than 12 weeks. And anecdotal reports from many of my colleagues suggested that it has been helpful for many patients over the long term. But there’s a lack of research on its longer-term safety and effectiveness. Phentermine is available as an inexpensive generic drug, but concerns have been raised about addiction and cardiovascular side effects due to its mode of action. The drug is a stimulant, so it’s possible it can increase blood pressure. We clearly needed more research to understand the benefits and risks of long-term use of phentermine.

Fill in that knowledge gap

In our new study, “Safety and Effectiveness of Longer-Term Phentermine Use: Clinical Outcomes from an Electronic Health Record Cohort,” published today in Obesity, my colleagues and I found evidence of better weight loss with longer-term phentermine use — up to 2 years follow up. And we found no association between prolonged use and the risk of cardiovascular disease or death up to 3 years after starting phentermine.

To conduct this study, we used electronic medical records from the Patient Outcomes Research to Advance Learning (PORTAL) cohort, which is part of the National Patient-Centered Clinical Research Network (PCORnet) initiative funded by the Patient-Centered Outcomes Research Institute (PCORI). is funded. This cohort included information from 8 health systems in the United States, including Kaiser Permanente (Southern California, Colorado, Northwest, Washington, Hawaii and Mid-Atlantic) and Denver Health and HealthPartners (in Minnesota). The study was led by my longtime collaborator Kristina Lewis, MD, MPH, SM at Wake Forest School of Medicine in Winston-Salem, NC.

We studied nearly 14,000 phentermine users, 8 out of 10 of whom were women. Her average BMI was 38, which is 235 pounds for a 5ft 6in person. But they included people with a BMI of just 27, which is 168 pounds for a 5ft 6in person. (Obesity starts at a BMI of 30.) Three out of 10 of them have been prescribed phentermine for more than 3 months. At 6 months, 1 year, and 2 years after starting phentermine, weight loss was clinically significantly greater in subjects taking the drug long-term (greater than 1 year) or intermediate-term (greater than 112 days but less than 1 year) than in subjects who have only used it for 3 months. The 144 people who used phentermine continuously for more than a year were off more than 7 percent of their baseline weight after 2 years.

It is important to monitor patients for their response to phentermine treatment. About a third of people prescribed phentermine lost less than 3 percent of their weight within the first 3 months of starting the drug. These “non-responders” should not continue treatment with phentermine as they are unlikely to derive any clinical benefit. In contrast, people who responded early to the drug — losing at least 3 percent of their weight within 3 months — tended to have greater long-term overall success in losing weight with the drug.

In terms of safety, we expected an increase in blood pressure, but instead found that systolic blood pressure was reduced in long-term phentermine users compared to short-term users at 24 months. It is possible that this reduction in blood pressure is due to sustained weight loss in the longer-term users of phentermine. Forty-one (0.3 percent) of 13,972 phentermine users experienced a serious adverse event (36 cardiovascular events; 5 deaths), but none were long-term users.

Implications for the treatment of obesity

Our study is limited because it is observational, not a randomized controlled trial, and has a relatively small sample of long-term users—and it did not address the issue of possible addiction. However, due to phentermine’s wide availability and low cost, our findings could have a significant impact on the treatment of obesity in people at low risk of heart disease.

Similar to what we’ve seen in studies of the combination drug Qsymia, it appears that some patients can safely maintain their long-term weight loss with phentermine alone. However, until we have a change in FDA guidance, longer-term prescribing of phentermine should be done off-label with full consideration of the legal and medical regulatory implications, which may vary from state to state.

More importantly, given the low cost of phentermine compared to other weight loss drugs, this study should motivate a future randomized trial to more definitively establish the long-term efficacy and safety of phentermine.