Best Numbing Cream For Lips? The 185 Detailed Answer

access denied

Your access to the NCBI website at www.ncbi.nlm.nih.gov has been suspended due to possible misuse/abuse of your website. This is not an indication of a security issue such as a virus or attack. It could be something as simple as a script running away or learning how to make better use of e-utilities http://www.ncbi.nlm.nih.gov/books/NBK25497/ to work more efficiently so that your work this does not affect the ability of other researchers to also use our website. To restore access and understand how you can better interact with our site to avoid this in the future, ask your system administrator to contact [email protected].

What is numbing cream? The main ingredient in numbing cream* (also in gel form) is lidocaine.

Do I need numbing cream? Most dermal fillers contain a small amount of lidocaine. In the past, some of our Newport Beach patients have requested topical numbing cream prior to treatment (particularly for lip fillers and lower eyelid/tear area treatments). While a numbing cream is not necessary, patients may experience less discomfort during treatment of sensitive areas if they are numbed before entering.

Does the anesthetic have any benefits? In fact, we have found that working without a topical anesthetic (particularly with botox injections) allows the injector to better capture the treatment area and achieve optimal results.

I have always been anesthetized prior to treatment in the past, can I continue to do so? Following a changed schedule, we will no longer be offering anesthesia in practice. For patients who still want an anesthetic before the treatment, we will be happy to request a prescription. To obtain a prescription for our topical anesthetic, please call our Newport Beach office today at (949) 644-1400.

Can you submit a prescription to my pharmacy? Prescriptions for our topical anesthetic are issued by the Healthcare Pharmacy of Tustin, located at 14642 Newport Ave, Tustin, CA 92780, USA. Orders can be shipped directly to you, or you can pick up your prescription at the pharmacy. Once you have requested a prescription, your information and prescription will be faxed to the pharmacy. Healthcare Pharmacy of Tustin will contact you directly regarding payment (please confirm your preferred shipping method). If you missed the call, please call (714) 669-4000 for assistance. Prescriptions are $29.95 plus shipping (prices subject to change).

I’ve thought about trying fillers under my eyes or adding volume to my lips. I’m also starting to notice my cheeks becoming more defined. How do I know where to stun?

Many patients are looking for eye fillers like Belotero to treat fine lines, cavities, and dark circles. For this under-eye area, apply a small amount of a topical anesthetic along the lower orbital rim (the upper part of the cheekbones). Do not apply too close to the eye and do not rub over the eyes after applying the anesthetic.

Add volume to lips with Restylane KYSSE, reduce fine lines/wrinkles around the lip line or accentuate frowns at the corners of the mouth. Prepare these areas by applying a small amount of numbing to the lip lines and just slightly above/below. Do not lick your lips after applying the anesthetic (do not ingest the local anesthetic).

Improve the appearance of your marionette lines (also known as nasolabial folds, lines that run from the corner of your nose down along the side of your mouth and down to your jawline). Apply the numbing agent directly along the line/crease in preparation for dermal filler application.

Cheeks becoming more pronounced and skin sagging? Numb along the mid/lower edge of the cheekbones and in the mid-crease area of ​​the cheeks for the application of Voluma. By replacing the volume in the middle surface, we can pick up and smooth out the bottom surface.

Patients looking for a specific pre-injection treatment plan can have a virtual consultation with Dr. Request Lavinia Chong. Our Patient Care Coordinator will provide you with an approximate cost estimate based on your consultation and will confirm that we have sufficient time at your next scheduled treatment appointment to complete the proposed treatment plan. *See below for additional instructions on how to use your local anesthetic.

Application of local anesthetics

Before coming to your appointment, prepare the treatment area by cleaning it with a gentle cleanser. Be sure to remove all oils, makeup, and dirt from the surface, then pat dry with a clean towel.

Please note: Do not apply anesthetic cream to blemishes or areas of skin that are irritated or have undergone chemical peels and/or procedures in the past 30 days. For our Facelift, Necklift, Eyelift, Browlift patients who are less than 30 days post-surgery, please contact our patient coordinator before using any topical anesthetic.

Apply a thin layer of local anesthetic* to the area you want to treat. We recommend wearing a glove for application or applying with a cotton swab. Be careful not to apply too close to the eye area. Please also be careful not to rub the product in your eyes. If you apply a local anesthetic to your lips, be careful not to lick your lips (do not take/swallow the local anesthetic). Please wash your hands thoroughly after use.

After 20-30 minutes have passed, you can wipe the local anesthetic off the skin surface with gauze/cloth.

Apply no earlier than 30 minutes before treatment. Some patients may wish to apply their topical anesthetic before commuting to the office in Orange County. For patients arriving from San Diego, Los Angeles, or the Inland Empire, you can choose to plan ahead, arrive early, apply numbing cream upon arrival, and simply relax in your car before your treatment time.

*Please report irritation, redness, itching to the practice.

Privacy Policy Close

Aspen Pharma Ireland Limited UK Branch Website Privacy Policy

Introduction to this Website Privacy Policy

This website (the “Website”) is owned and operated by Aspen Pharma Ireland Limited UK Branch (“Aspen UK”). At Aspen UK, we have a unique culture that sets us apart. We are committed to patients, healthcare professionals and alliance partners, our employees and the community. Protection of personal data and respect for privacy are fundamental parts of that commitment and this Privacy Policy below helps demonstrate that commitment to visitors and users of Aspen UK websites. That is why we have implemented this website privacy policy (“Privacy Policy”). Aspen UK provides this Privacy Policy to explain how we collect, use, disclose and protect the personal information that you give us when you access and use the Website. Aspen UK is the data controller within the meaning of applicable data protection legislation. Aspen UK websites are an Aspen UK controlled web program owned, approved and/or targeted by Aspen UK on behalf of Aspen UK.

In general, by not providing any personal information, you can visit the website and view its content while remaining anonymous. If you do not agree to this privacy policy, please do not provide us with any information or use the website.

As used in this Privacy Policy, “we”, “our” and “us” refer to Aspen UK and its affiliates.

The importance of personal data

“Personal Data” is defined in the data protection laws applicable in your country. They contain all information relating to an identified or identifiable natural person. This means any individual who is identified, directly or indirectly, by association with an identifier such as name, identification number, location data, online identifiers (e.g. IP addresses – if they can be used to identify you) or one or more factors can be specific to the physical, physiological, genetic, mental, economic, cultural or social identity of that natural person.

Put simply, this is information that can be used to identify you, either on its own or together with other information we hold or have available to us.

Important notice about international transfers

We are part of the Aspen Group which has databases in various jurisdictions. We may transfer your data to one of the group’s databases outside your country of residence. These other countries either have different data protection laws than your country of residence or they do not have data protection laws. They may not be considered by the European Commission to provide an adequate level of protection for personal data. Even if the country to which the data is to be transferred does not require us to provide an adequate level of protection for your data, we will still attempt to ensure that data transfers to the Aspen Group databases in that country are adequately protected.

The categories of personal data we may collect, the purpose and the legal basis

Personal data collected from you includes:

Categories of personal data Purpose Legal basis Browsing information (IP address, browser information) Monitoring and generating statistical information on the use of our platforms and analyzing and improving their functionality. Legitimate Interests – We need to carry out this limited routine monitoring to ensure our website is working properly, to diagnose problems with our server and to administer our website.

Follow the instructions of law enforcement, a court of law, or any other entity required by law

For our general records and customer relationship management.

Administering the proposed sale, reorganization or merger of any or all parts of our business, including responding to inquiries from the prospective buyer or the merging entity.

Resolving any Complaints or Disputes with You. Legitimate interest (see left column)

In summary, we require certain categories of personal data as this is necessary to administer a contract with you (if applicable). Certain other personal data is processed for our legitimate interests when it is not harmful to you.

Data Anonymization and Use of Aggregated Information

We may convert your personal information into statistical or aggregated information in a manner that ensures that you are not identified or identifiable from that information. We may use this aggregated data to conduct market research and analysis, including to compile statistical research and reports.

In particular, we use technology to collect anonymous information about the use of this website. For example:

1. We use technology to track which pages of our website visitors see. We also use technology to determine which web browsers our visitors are using. This technology does not identify you personally, it only allows us to compile statistics about our visitors and how they use our website.

2. Certain pages of this website may contain hyperlinks to other pages. We may use technology to track how often these links are used and which pages of our website our visitors select. Again, this technology does not identify you personally – it only allows us to compile statistics on the use of these hyperlinks.

We use this anonymous data to improve the content and functionality of this website, and to address areas and topics of interest so that we can focus our email updates (for those who wish to receive such communications). This allows us to better understand the areas of interest of our website visitors in general and therefore improve our website and the products and services we offer.

Cookies and analysis tools

We may use cookies on our website from time to time. Cookies are small text files that your web browser leaves on your hard drive to recognize you as a repeat user of our website, to track your use of our website, and to target advertising. This enables certain aspects of your visit to our website to be personalised. Information collected by cookies in this way is only used on an aggregate basis. If a visitor does not expressly inform us of his identity, e.g. by registering on our website, providing information via an online form, or sending us correspondence from the website, we will not know the identity of individual visitors. We may use cookies to store preferences; record session information; develop information about the preferences and interests of website visitors; record previous activity on a website in order to provide a better service when you return to our website; or customize the content of web pages based on information you voluntarily provide.

The cookies that our websites may set fall into four categories:

1. Strictly Necessary Cookies

These cookies are essential as they enable you to move around our websites and use certain features, e.g. B. to access secure areas of the website or in connection with information searches. Without these cookies, certain services that you may request could not be provided.

2. Performance Cookies

These cookies can be used to collect information about how you use our websites, for example which pages you visit most often. These cookies do not collect any information that identifies you. These cookies are only used to learn how our websites work and to make relevant improvements.

3. Functionality and Profiling Cookies

These cookies can be used to enable our websites to store information about choices you make and to provide you with more personal features. We may also use such cookies to ensure that onsite marketing and experiences are relevant to you. The information these cookies collect may be anonymous and they cannot track your browsing activity on other websites.

4. Advertising Cookies

These cookies can be used to deliver advertisements that are more relevant to you and your interests. They are usually placed by advertising networks with our permission.

We use Google Analytics, a web analytics service provided by Google Inc. (Google), on our website. Google Analytics uses cookies, i.e. text files that are stored on your computer and enable an analysis of your use of the website. The information generated by the cookie about your use of this website is usually transmitted to a Google server in the USA and stored there. If IP anonymization is activated on this website, your IP address will be shortened beforehand by Google within member states of the European Union or in other contracting states of the Agreement on the European Economic Area. Only in exceptional cases will the full IP address be sent to a Google server in the USA and shortened there. On behalf of the operator of this website, Google will use this information to evaluate your use of the website, to compile reports on website activity and to provide other services related to website activity and internet usage to the website operator. The IP address transmitted by your browser as part of Google Analytics will not be merged with other Google data. You can prevent the storage of cookies by setting your browser software accordingly; we would like to point out to you however that in this case you will if applicable not be able to use all functions of this website in full. You can also prevent Google from collecting and processing the data generated by the cookie and related to your use of the website (including your IP address) by downloading and installing a browser plug-in from the following link: http:// / tools.google.com/dlpage/gaoptout?hl=en

We use Google Analytics with the extension “anonymizeIP()” on our site, whereby IP addresses are processed in abbreviated form in order to rule out direct personal reference.

You can deactivate cookies via the settings of your internet browser. Please consult your browser’s help function for information on disabling cookies. Note that certain features of our website may not work properly if you disable cookies.

Facebook pixel

We use the “Facebook Pixel” from Facebook Inc. (“Facebook”).

This allows user behavior to be tracked after they have been redirected to the provider’s website by clicking on a Facebook ad. This allows us to measure the effectiveness of Facebook ads for statistical and market research purposes. This data is also stored and processed by Facebook, which is why we are informing you to the best of our knowledge. Facebook can link this information to your Facebook account and also use it for its own advertising purposes, in accordance with Facebook’s data usage guidelines https://www.facebook.com/about/privacy/. You can allow Facebook and its partners to place ads on and off Facebook. A cookie can also be stored on your computer for these purposes.

This feature also enables us to show users of the website personalized advertisements (“Facebook Ads”) when they visit Facebook or other websites that also use this feature. We are interested in showing you personalized advertising in order to make our website more interesting for you. We do not use a “Facebook Custom Audience Customer List”. Due to the “Facebook Custom Audiences Pixel”, your browser automatically establishes a direct connection to the Facebook servers. We have no influence on the scope and further use of the data collected by Facebook through the use of this function and are therefore informing you according to our state of knowledge: By integrating the “Facebook Custom Audiences Pixel” Facebook receives the following information: HTTP header , pixel specific data, button click data, optional information and form field name (see https://www.facebook.com/business/gdpr for details). If you are registered with Facebook, Facebook can assign your visit to our website to your user account. Even if you are not registered with Facebook or have not logged in, there is a possibility that Facebook will find out and store your IP address and other identifiers in order to track you.

You can object to participation in the “Facebook Pixel” by clicking on https://www.facebook.com/settings?tab=ads.

The legal basis for the processing of your personal data is Art. 6 (1) (f) GDPR. You can find more information on data processing by Facebook at https://www.facebook.com/about/privacy. Facebook is certified under the Privacy Shield Agreement and thereby guarantees compliance with European data protection law: (https://www.privacyshield.gov/participant?id=a2zt0000000GnywAAC&status=Active).

Disclosure of your personal data to third parties

We may share your personal information with third parties including but not limited to:

1. within our group of companies for the purposes described in this privacy policy;

2. to third parties who provide services to us and help us and our group of companies to operate our business. For example, sometimes a third party may have access to your personal information to support our information technology;

3. to our legal and other professional advisers;

4. to the extent necessary to comply with a legal obligation, to protect vital interests, to protect the security or integrity of our databases or this website, to protect against legal liability;

5. to regulators, courts and governmental agencies to comply with legal orders, legal or regulatory requests and governmental requests; and

Security of Personal Information

We strive to implement appropriate technical and physical security measures to protect personal data transmitted, stored or otherwise processed by us from accidental or unlawful destruction, loss, alteration, unauthorized disclosure or unauthorized access in connection with our website. These measures include computer protection measures and secured files and facilities. Our service providers are also carefully selected and encouraged to use appropriate protective measures. In certain areas, Aspen UK uses industry standard SSL encryption to protect data transmissions. Most current browsers support the level of security required to use these areas.

In particular, we endeavor to take appropriate technical and organizational measures to ensure a level of security appropriate to the risk, including where appropriate: (a) pseudonymization (e.g. where data is separated from direct identifiers so that it cannot be linked to an identity is without additional information, which is kept separately) and encryption, (b) ensuring the ongoing confidentiality, integrity, availability and resilience of systems and services used to process your personal data, (c) ensuring the ability, availability and restore access to personal data in a timely manner in the event of a physical or technical incident; and (d) ensuring a process for regularly testing, evaluating and assessing the effectiveness of technical and organizational security measures.

Retention period or criteria for determining the retention period

We keep your personal data for as long as necessary to fulfill the purposes for which it was collected as described above.

The criteria we use to determine data retention periods for personal information include the following: (i) retention in case of requests. We will keep them for a reasonable period after the relationship between us has ended (up to 6 months) in case of any requests from you; (ii) Retention in Case of Damage. We will keep it for the period during which you have legal claims against us (in Germany this means we keep it for 10 years) if and to the extent that we have entered into a contract with you; (iii) Storage in accordance with legal and regulatory requirements. We will assess whether we are required by law or regulation to keep it after the period described in (ii).

If your application is successful and you take up employment with Aspen UK, your personal data will be transferred to your personnel file and processed for employment purposes. If your application for a job is unsuccessful, we will retain your personal data for a period consistent with applicable law after notification that your application was unsuccessful.

If you would like more information about our data retention practices, please contact us (see “Contact Us” below).

Your rights under data protection laws

You have various rights under data protection laws in your country. These may include (where applicable): the right to request access to the personal data we hold about you; the right to rectification, including to request that we correct inaccurate personal data; the right to request the restriction of processing concerning you or to object to the processing of your personal data, the right to request the erasure of your personal data when we no longer need to keep it; the right to data portability, including receiving personal data in a commonly used machine-readable format in certain circumstances, e.g. B. where our processing is based on consent; the right to object to automated decision-making, including profiling (if any), which produces legal or significant effects on you as an individual; and the right to withdraw your consent to processing for which you have previously given such consent. Please note that some of these rights will only become relevant once changes in data protection laws come into force in May 2018. You can also lodge a complaint with a supervisory authority in your country of residence.

Please read “Contact Us” if you wish to exercise any of these rights (where relevant).

Links to Other Sites

This website may contain hyperlinks to websites that are not operated by us. These hyperlinks are provided for your information and convenience only and do not imply any endorsement of the activities of these third party websites or any association with their operators. We do not control these websites and are not responsible for their data or privacy practices. We urge you to read any privacy policy posted on any website you visit before using the website or providing any personal information.

Updated and changed to this privacy policy

We may decide to change this privacy policy. If the change is fundamental or may significantly affect you, we will provide you with the updated Privacy Policy prior to the change actually taking effect. We encourage you to periodically review the content of this Privacy Policy.

contact details

If you have any questions or complaints about our compliance with this Privacy Policy, or if you have any recommendations or comments to improve the quality of our Privacy Policy, please contact us at:

Email: [email protected]

Public Science Service Telephone: +44 1748 828391

There are terms and conditions associated with your use and display of this website. These can be accessed by clicking on the “Terms of Use” link in the footer of the website (next to “Privacy Policy”).

Be sure to include your email address and phone number in your correspondence.

Alternatively write to: Aspen UK, 6 Bell Street, Maidenhead, Berkshire, SL6 1BU

Last updated: July 2018

A doctor or nurse will usually write you a prescription for lidocaine cream or the cream itself before your appointment. Always follow the directions that come with your cream.

If you are having an IV drip or blood drawn, apply the lidocaine cream 1 hour before.

For minor procedures, your doctor may tell you to apply the cream more than 1 hour before the procedure.

If the procedure is delayed and the numbing effect of the cream has worn off, ask your doctor or nurse for advice before applying any more creams.

If you are having a cosmetic procedure and purchased lidocaine from a pharmacy to numb the area, let the person performing the procedure know before it begins. It will help them know the area has been numbed and you will feel less pain.

How much to use

The amount you use depends on the procedure you have and the type of lidocaine cream you use.

Read the instructions that come with the cream or follow the advice of your doctor or nurse.

They may tell you to apply an entire tube of cream to each area of ​​your skin, more than one tube, or just part of a tube.

How to put it on

Orael

Generic Name: Benzocaine Topical [ BENZ-oh-kane-TOP-ik-al ]

Drug class: local anesthetics

Medically verified by Drugs.com. Last updated on June 14, 2022.

What is Orazel?

Orajel contains benzocaine, a local anesthetic (numbing drug). It works by blocking nerve signals in your body.

Orajel numbs the skin or surfaces in the mouth and is used to temporarily relieve pain from a sore throat, canker sore, cold sore, cold sore, mild irritation or injury to the mouth and gums.

Orajel is also used for temporary relief of gum inflammation in children aged 2 years and older.

warnings

Using Orajel by mouth can lead to a condition where the oxygen levels in your body tissues can become dangerously low. This is a potentially fatal condition called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a). Do not use this medicine if you have ever had methaemoglobinaemia.

Get emergency medical help if you have symptoms of methemoglobinemia: headache, tiredness, confusion, rapid heart rate, and feeling light-headed or short of breath, with a pale, blue, or gray appearance of your skin, lips, or fingernails.

Benzocaine overdose can cause deadly side effects if too much of the drug is absorbed through your skin and into your blood. Use the smallest amount needed.

Do not use Orajel on a child under 2 years old.

Before taking this medicine

Do not use Orajel if you have ever had methaemoglobinaemia in the past.

Do not use Orajel on a child under 2 years old.

Benzocaine overdose can cause deadly side effects if too much of the drug is absorbed through your skin and into your blood. This can happen if you apply more than the recommended dose.

Ask a doctor or pharmacist if it is safe to use this medicine if you have:

a personal or family history of methemoglobinemia or a genetic (hereditary) enzyme deficiency;

asthma, bronchitis, emphysema, or other breathing disorders;

heart disease; or

if you smoke

Ask a doctor before using Orajel if you are pregnant or breastfeeding.

When applying Orajel to your breast, avoid areas that may come into contact with the baby’s mouth.

How should I use Orajel?

Use Orajel exactly as directed on the label or as directed by your doctor. Read all medication guides or directions for use.

Your body can absorb more benzocaine if you use too much if you apply it to large areas of skin.

Use the smallest amount needed to numb skin or relieve pain. Do not use large amounts of Orajel. Do not cover treated skin areas with plastic wrap without medical advice.

Do not use Orajel to treat large areas of skin or deep puncture wounds. Avoid using the medicine on rough or blistered skin, such as B. severe burns or abrasions.

Call your doctor if your symptoms do not improve or worsen within the first 7 days of using Orajel. Also call your doctor if your symptoms have gone away but then come back.

If you’re treating a sore throat, call your doctor if the pain is severe or lasts more than 2 days, especially if you also develop a fever, headache, rash, swelling, nausea, vomiting, cough, or trouble breathing.

Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Because Orajel is used when needed, you may not have a dosing schedule. Skip any missed dose if it is almost time for your next dose.

What happens if I overdose?

See an ambulance or call the poison control center at 1-800-222-1222. An overdose of benzocaine applied topically to the skin can cause life-threatening side effects such as an irregular heartbeat, seizures, coma, slow breathing, or respiratory failure (not breathing).

What should I avoid when using Orajel?

Avoid eating on your gums or in your mouth within 1 hour of using Orajel.

Avoid getting Orajel in your eyes. Avoid swallowing the gel while applying it to your gums or the inside of your mouth.

Orajel side effects

Using Orajel by mouth can lead to a condition where the oxygen levels in your body tissues can become dangerously low. This is a potentially fatal condition called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a). This condition can occur after just one use of benzocaine or after multiple uses.

Signs and symptoms can appear within minutes or up to 2 hours after applying Orajel to the mouth or throat. GET EMERGENCY MEDICAL ASSISTANCE IF YOU:

headache, fatigue, confusion;

rapid heartbeat;

feeling lightheaded or short of breath; and

pale, blue or gray appearance of your skin, lips or fingernails.

Get emergency medical help if you have any signs of an allergic reaction to Orajel: hives; difficult breathing; swelling of the face, lips, tongue or throat.

Stop using this medicine and call your doctor at once if you have:

severe burning, stinging or tenderness where the medicine is applied;

swelling, warmth, or redness; or

Weeping, blistering, or signs of infection.

Common side effects of Orajel may include:

mild stinging, burning or itching where the medicine is applied;

skin sensitivity or redness; or

dry white flakes where the medicine was applied.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

What other drugs will affect Orajel?

Medicines used on the skin are unlikely to be affected by other medicines you are using. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

References Orajel product label

Further information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use Orajel only for the prescribed indication.

Always check with your doctor to ensure that the information presented on this page is appropriate for your personal circumstances.

Medical Disclaimer

Copyright 1996-2022 Cerner Multum, Inc. Version: 7.01.

DESCRIPTION Lidocaine Ointment USP, 5% contains a local anesthetic and is administered topically. See INDICATIONS AND USE for specific applications. Lidocaine Ointment USP, 5% contains Lidocaine USP, which is chemically named acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)- and has the following structural formula: Composition of Lidocaine Ointment USP, 5%: Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, (lidocaine) 5% in a water-miscible ointment vehicle containing polyethylene glycols.

CLINICAL PHARMACOLOGY Mechanism of action Lidocaine stabilizes the neuronal membrane by inhibiting the ion fluxes required for impulse initiation and propagation, thereby inducing a local anesthetic effect. Beginning of anesthesia Lidocaine ointment 5% produces a local, topical anaesthetic. The onset of action is 3 to 5 minutes. It is ineffective if applied to intact skin. Hemodynamics Excessive blood levels can cause changes in cardiac output, total peripheral resistance and mean arterial pressure. These changes can be attributed to a direct depressant effect of the local anesthetic on various components of the cardiovascular system. Pharmacokinetics and metabolism Lidocaine can be absorbed from the mucous membranes after topical administration, with the rate and extent of absorption depending on the specific site of application, duration of exposure, concentration and total dose. In general, the rate of absorption of local anesthetics after topical application is fastest after intratracheal administration. Lidocaine is also well absorbed from the gastrointestinal tract, but little intact drug appears in the circulation due to biotransformation in the liver. Lidocaine is rapidly metabolized by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, amide bond cleavage and conjugation. N-Dealkylation, a major biotransformation pathway, leads to the metabolites monoethylglycine xylidide and glycine xylidide. The pharmacological/toxicological effects of these metabolites are similar to, but less potent than, those of lidocaine. About 90% of the administered lidocaine is excreted as various metabolites and less than 10% is excreted unchanged. The primary urinary metabolite is a conjugate of 4-hydroxy-2,6-dimethylaniline. The plasma binding of lidocaine is dependent on the drug concentration and the bound fraction decreases with increasing concentration. At concentrations of 1 to 4 µg free base per ml, 60 to 80 percent of lidocaine is protein bound. Binding is also dependent on the plasma concentration of alpha-L-acid glycoprotein. Lidocaine crosses the blood-brain and placenta barriers, presumably by passive diffusion. Studies on the metabolism of lidocaine following intravenous bolus injections have shown that the elimination half-life of this active substance is typically 1.5 to 2 hours. Due to lidocaine’s rapid rate of metabolism, any condition that impairs liver function can alter the kinetics of lidocaine. In patients with hepatic impairment, the half-life may be twofold or more prolonged. Renal impairment does not affect the kinetics of lidocaine but may increase the accumulation of metabolites. Factors such as acidosis and use of CNS stimulants and depressants affect the CNS levels of lidocaine required to produce overt systemic effects. Objective side effects become increasingly evident with increasing venous plasma levels above 6 mcg free base per ml. In rhesus monkeys, arterial blood levels of 18-21 mcg/ml have been shown to be the threshold for convulsive activity.

INDICATIONS AND USE Lidocaine ointment 5% is indicated for anesthesia of accessible mucous membranes of the oropharynx. It is also useful as an anesthetic lubricant for intubation and for temporary relief of pain associated with minor burns, including sunburn, abrasions and insect bites.

CONTRAINDICATIONS Lidocaine is contraindicated in patients with known hypersensitivity to amide-type local anesthetics or to other components of Lidocaine Ointment 5%.

WARNINGS EXCESSIVE DOSAGE OR SHORT INTERVALS BETWEEN DOGS MAY LEAD TO HIGH PLASMA LEVELS AND SERIOUS SIDE EFFECTS. PATIENTS SHOULD BE INSTRUCTED TO STRICTLY FOLLOW THE DOSAGE AND DIRECTIONS SET FORTH IN THIS PACKAGE LEAFLET. TREATMENT OF SEVERE SIDE EFFECTS MAY REQUIRE RESUSCITATION, OXYGEN AND OTHER REVITALIZING DEVICES. Lidocaine ointment 5% should be used with extreme caution in the presence of sepsis or severely traumatized mucosa at the site of application, since under such conditions there is a possibility of rapid systemic absorption. Methaemoglobinaemia Cases of methaemoglobinaemia have been reported in association with the use of local anaesthetics. Although all patients are at risk of methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary impairment, infants under 6 months of age and concomitant exposure to oxidizing agents or their metabolites are more prone to develop clinical manifestations the disease. If local anesthetics need to be used in these patients, close monitoring for symptoms and signs of methaemoglobinaemia is recommended. Signs of methaemoglobinaemia may appear immediately or a few hours after exposure and are characterized by cyanotic skin discoloration and/or abnormal blood staining. Methemoglobin levels may continue to rise; Prompt treatment is therefore required to avert more serious central nervous system and cardiovascular side effects, including seizures, coma, arrhythmias, and death. Discontinue lidocaine ointment 5% and all other oxidizing agents. Depending on the severity of signs and symptoms, patients may respond to supportive measures, i. H. Oxygen therapy, hydration. A more severe clinical presentation may require treatment with methylene blue, exchange transfusion, or hyperbaric oxygen.

PRECAUTIONS General The safety and effectiveness of lidocaine depend on proper dosage, technique, proper precautions, and preparedness for emergencies (see WARNINGS and ADVERSE REACTIONS). The lowest dose that produces effective anesthesia should be used to avoid high plasma levels and serious side effects. Repeated doses of lidocaine can result in significant increases in blood levels with each repeated dose due to the slow accumulation of the drug and/or its metabolites. Tolerance to elevated blood levels varies with the patient’s status. Debilitated, elderly patients, acutely ill patients and children should receive reduced doses according to their age and physical condition. Lidocaine should also be used with caution in patients with severe shock or heart block. Lidocaine ointment 5% should be used with caution in patients with known drug intolerance. Patients allergic to para-aminobenzoic acid derivatives (procaine, tetracaine, benzocaine, etc.) have not shown cross-sensitivity to lidocaine. Many drugs used during the administration of anesthesia are considered potential triggers of familial malignant hyperthermia. Since it is not known whether amide-type local anesthetics can induce this reaction and since the need for additional general anesthesia cannot be predicted in advance, it is suggested that a standard protocol for the management of malignant hyperthermia should be available. Early unexplained signs of tachycardia, tachypnea, labile blood pressure, and metabolic acidosis may precede a rise in temperature. A successful outcome depends on early diagnosis, prompt discontinuation of the suspected causative agent(s), and initiation of treatment, including oxygen therapy, supportive measures as indicated, and dantrolene (read Dantrolene sodium intravenous package insert before use) . Drug Interactions Patients receiving local anesthetics are at an increased risk of developing methemoglobinaemia when concomitantly exposed to the following drugs, which may include other local anesthetics: Examples of drugs associated with methemoglobinaemia: Class examples nitrates/nitrites nitroglycerin, nitroprusside , Nitric Oxide, Nitrous Oxide Local Anesthetics Benzocaine, Lidocaine, Bupivacaine, Mepivacaine, Tetracaine, Prilocaine, Procaine, Articaine Antineoplastic Agents Cyclophosphamide, Flutamide, Rasburicase, Ifosfamide, Hydroxyurea Antibiotics Dapsone, Sulfonamides, Nitrofurantoin,

para-aminosalicylic acid antimalarials chloroquine, primaquine anticonvulsants phenytoin, sodium valproate, phenobarbital Other drugs acetaminophen, metoclopramide, sulfonamides (i.e. sulfasalazine), quinine used in local anesthesia may interfere with swallowing, thereby increasing the risk of aspiration. For this reason, no food should be taken for 60 minutes after the application of local anesthetic preparations in the mouth and throat area. This is especially important in children because of their frequency of eating. Numbness of the tongue or oral mucosa can increase the risk of accidental bite trauma. Food and chewing gum should not be taken while the mouth or throat is numbed. Educate patients that the use of local anesthetics can cause methemoglobinemia, a serious condition that requires prompt treatment. Advise patients or caregivers to seek medical attention immediately if they or anyone in their care experiences the following signs or symptoms: pale, gray, or blue-colored skin (cyanosis); Headache; rapid heart rate; Shortness of breath; drowsiness; or tiredness. Carcinogenesis, mutagenesis, impairment of fertility Animal studies with lidocaine to evaluate carcinogenic and mutagenic potential or effects on fertility have not been performed. Use in pregnancy Teratogenic effects. Pregnancy category B. Reproductive studies were performed in rats at doses up to 6.6 times the human dose and revealed no evidence of fetal harm from lidocaine. However, there are no adequate and well-controlled studies in pregnant women. Animal reproduction studies are not always predictive of human response. This fact should be considered before administering lidocaine to women of childbearing potential in general, especially during early pregnancy when maximum organogenesis occurs. Labor and delivery Lidocaine is not contraindicated in labor and delivery. When using lidocaine ointment 5% concomitantly with other products containing lidocaine, the total dose of all formulations must be taken into account. Breastfeeding mothers It is not known whether this medicine is excreted in breast milk. Because many drugs are excreted in human milk, caution should be exercised when administering lidocaine to a breastfeeding woman. Pediatric use The dosage in children should be reduced according to age, body weight and physical condition. Caution should be exercised when applying lidocaine ointment 5% to large areas of broken or abraded skin to avoid overdose, as systemic absorption of lidocaine may be increased in such conditions (see DOSAGE AND ADMINISTRATION).

ADVERSE REACTIONS Adverse reactions following lidocaine administration are similar to those observed with other amide local anesthetics. These side effects are generally dose dependent and may result from high plasma levels caused by overdosing or rapid absorption, or may result from hypersensitivity, idiosyncrasy or decreased tolerance on the part of the patient. Serious side effects are generally systemic in nature. The following types are the most commonly reported: CNS manifestations of the central nervous system are excitable and/or depressant and may be characterized by drowsiness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, Cold or numbness, twitching, tremors, convulsions, loss of consciousness, respiratory depression and respiratory arrest. The excitatory manifestations can be very brief or not appear at all, in which case the first manifestation of toxicity can be drowsiness, which progresses to unconsciousness and respiratory arrest. Drowsiness after lidocaine administration is usually an early sign of high blood levels of the drug and may occur as a result of rapid absorption. Cardiovascular system Cardiovascular manifestations are usually debilitating and characterized by bradycardia, hypotension and cardiovascular collapse, which can lead to cardiac arrest. Allergic Allergic reactions are characterized by skin lesions, urticaria, edema or anaphylactoid reactions. Allergic reactions can occur as a result of hypersensitivity to the local anesthetic or other components of the formulation. Allergic reactions resulting from hypersensitivity to lidocaine are extremely rare and, if they occur, should be treated by conventional means. Detection of susceptibility by skin testing is of dubious value. To report SUSPECTED SIDE EFFECTS, contact Amneal Pharmaceuticals at 1-877-835-5472 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

OVERDOSE Acute emergencies due to local anesthetics are generally associated with high plasma levels occurring during therapeutic use of local anesthetics (see ADVERSE REACTIONS, WARNINGS and PRECAUTIONS). Management of local anesthetic emergencies The first consideration is prevention, which is best achieved through careful and constant monitoring of the patient’s vital cardiovascular and respiratory signs and level of consciousness after each local anesthetic administration. Oxygen should be given at the first sign of change. The first step in treating seizures is immediate attention to maintaining a patent airway and assisted or controlled ventilation with oxygen and a delivery system that provides immediate positive airway pressure through a mask. Circulatory adequacy should be checked immediately after initiation of these ventilations, bearing in mind that drugs used to treat seizures sometimes decrease circulation when administered intravenously. If the convulsions persist despite adequate respiratory support, and if circulatory status allows, small doses of an ultra-short-acting barbiturate (such as thiopental or thiamylal) or a benzodiazepine (such as diazepam) can be given intravenously. The doctor should be familiar with these anticonvulsants before using local anesthetics. The administration of intravenous fluids and possibly a vasopressor, depending on the clinical situation (e.g. ephedrine), may be necessary to support the treatment of circulatory depression. If not treated promptly, both convulsions and cardiovascular depression can lead to hypoxia, acidosis, bradycardia, arrhythmias, and cardiac arrest. If cardiac arrest occurs, standard CPR should be instituted. Dialysis is of negligible value in the treatment of acute lidocaine overdose. The oral LD50 of lidocaine HCl in fed female rats is 459 (346 to 773) mg/kg (as salt) and 214 (159 to 324) mg/kg (as salt) in fasted female rats.

DOSAGE AND ADMINISTRATION When Lidocaine Ointment 5% is used concomitantly with other products containing lidocaine, the total dose of all formulations must be considered. Adults A single application should not exceed 5 g lidocaine ointment 5% with 250 mg lidocaine base (corresponding chemically to around 300 mg lidocaine hydrochloride). This is approximately equivalent to squeezing a six (6) inch length of ointment from the tube. For a 70 kg adult, this dose is equivalent to 3.6 mg/kg (1.6 mg/lb) of lidocaine base. No more than half a tube, approximately 17 g to 20 g of ointment or 850 mg to 1000 mg of lidocaine base, should be administered in one day. Although the incidence of side effects with lidocaine ointment 5% is quite low, caution should be exercised, particularly when using large amounts, as the incidence of side effects is directly proportional to the total dose of local anesthetic administered. Dosage for children It is difficult to recommend a maximum dose of a drug for children, as this varies with age and weight. For children under ten years of age who have normal lean body mass and development, the maximum dose can be determined using one of the standard pediatric drug formulations (e.g. Clark’s rule). For example, the dose of lidocaine in a 5-year-old child weighing 50 lbs should not exceed 75 mg to 100 mg when calculated using Clark’s rule. In any event, the maximum amount of lidocaine administered should not exceed 4.5 mg/kg (2 mg/lb) body weight. For medicinal use, apply topically to adequately control symptoms. The use of a sterile gauze swab is recommended for use on injured skin tissue. Apply to tube prior to intubation. In dentistry, apply to previously dried oral mucosa. Subsequent removal of excess saliva with cotton rolls or a saliva ejector minimizes dilution of the ointment, allows for maximum penetration, and minimizes the possibility of the topical ointment being swallowed. For use in connection with the insertion of new dentures, apply to all denture surfaces that come into contact with mucosa. IMPORTANT: Patients should consult a dentist every 48 hours during fitting.

FORM OF SUPPLY Lidocaine Ointment USP, 5% is supplied as a white to off-white ointment. It is available as follows: 30g laminated tubes with child resistant closure, NDC 65162-918-30. 35.44 g (1¼ oz) laminate tubes with child-resistant closures, NDC 65162-918-38. 50 g (1 ¾ oz) double wall container with child resistant closure, NDC 65162-918-53. Pharmacist: When dispensing to a consumer, provide child-resistant packaging for dispensing. Store at 20° to 25°C (68° to 77°F); Allowable between 15°C and 30°C (59°F to 86°F) [see USP Controlled Room Temperature]. Distributed by: Amneal Pharmaceuticals LLC Bridgewater, NJ 08807 Rev. 10-2018-08

The use of lidocaine cream often depends on the strength. Lidocaine 4% comes in a cream or patch and is typically used to help with pain relief in muscles and joints. It is helpful for people with back pain, sore muscles and mild joint pain. Lidocaine cream 5% is available OTC to help with itching and pain caused by hemorrhoids.

Because lidocaine cream temporarily numbs the skin and reduces pain, it has a few other uses besides muscle pain and hemorrhoid irritation. Lidocaine cream is also used by tattoo artists and laser hair removal clinics to relieve pain before potentially painful procedures. Lidocaine cream can also be used before certain cosmetic procedures, such as laser skin resurfacing and needle-based facials.

Orajel can be bought at any pharmacy without a prescription, but how long does it last for a toothache? Does it only work for mild toothache or also for severe toothache? Our Long Island City dentists will tell you the whole truth and nothing but the truth.

How long does Orazel last?

According to the labels on the three most popular Orajel products, there is no officially stated duration of action. I would like to reiterate that there is no statement on the product label as to how long the effects of Orajel will last.

To prove this to you, we’ll go through all three products. What ingredients are in them and what are their stated effects.

Orajel – drug for toothache gel

This particular product is designed to provide instant pain relief for mild toothaches only. There is no mention of how long Orajel will last for pain relief.

10% benzocaine to relieve mouth pain

Provides instant pain relief

Easy to use

Ingredients:

10% benzocaine – oral pain reliever

Orajel 3X Medicated for Toothache & Gum Gel

This product is intended for toothache and sore gums. The 3X doesn’t mean it has triple the potency, it means it has 3 ingredients. There is no mention of how long Oraljel 3x will last for pain relief.

20% benzocaine to relieve mouth pain

Cooling relief to soothe gums

Relieves gum irritation

Ingredients:

Benzocaine 20% – oral pain reliever

Menthol 0.26% – oral pain reliever

Zinc chloride 0.15% – oral astringent

Orajel 4X Medicated for Toothache & Gum Gel

This product aims to provide instant pain relief from severe toothache and sore gums. The 4X doesn’t mean it’s four times as effective, it means it contains four ingredients. There is no mention of how long Orajel 4x will last for pain relief.

Clinical strength pain relief

Proven to kill harmful bacteria

Helps prevent infections

Cooling relief for irritated gums

Ingredients:

Benzalkonium chloride 0.13% – oral antiseptic

Benzocaine 20% – oral pain reliever

Menthol 0.5% – oral pain reliever

Zinc chloride 0.15% – oral astringent

Comparison of the 3 Orajel products

The strongest Orajel product is the 4X and it has over four times the ingredients of the original. The 4X also has one more ingredient than the 3X and slightly higher concentrations. The concentration of benzocaine, the main narcotic, appears to have exceeded 20% at both 3X and 4X. The menthol provides a cooling sensation that can help the numbing effect a bit, similar to using an ice pack.

Is there a way to find out how long the Orajel pain relief lasts?

Even though Orajel doesn’t tell us how long the effects last, we can still find out through extrapolated knowledge and clinical studies. You may be surprised, but our Long Island City dentists actually use a product that contains nearly identical ingredients to Orajel.

The product we use as a numbing gel contains the same ingredient as Orajel, which is 20% benzocaine. The only difference is that this cannot be purchased over the counter and a dental license is required. Although you may not be able to buy it, the ingredient is identical.

The only ingredient in topical anesthetics that can numb the tooth and gums is benzocaine, so we should investigate studies into this.

Studies on the duration of the anesthetic effects of benzocaine

The first study showed that a 20% concentration of benzocaine takes about 30 seconds to produce a numbing effect. Then it took another 2-3 minutes to get the full depth and intensity of the anesthetic. After that, the anesthetic lasted 5-15 minutes.

The second study found that benzocaine typically had a rapid onset of less than 1 minute before the anesthetic took effect. Then the total effective duration of the anesthetic was between 5 and 10 minutes.

Conclusion based on the two studies

According to both studies, the numbing effect of benzocaine can last up to 20 minutes at most. Because Orajel contains the exact same ingredient, we can confidently say that Orajel can last up to 20 minutes with each use.

How long does Orajel last in clinical practice?

In case you didn’t want to believe the two studies above, we can bring you real life evidence of how long Orajel lasts and how effective it is at numbing your teeth.

Your dentist will use the Orajel-like product as a pre-numbing gel. Emphasis on the fact that this is a PRE numbing gel and not a numbing gel. This is what your dentist uses to numb your tooth.

Dry the gums with a piece of gauze. Apply the Orajel to a cotton swab and rub onto the gums. Leave the gel on for 1-2 minutes. Numb the tooth with an injection from a dental needle.

If you remember the last time you had a tooth filling, the 4 steps above were the flow of the procedure. Even after using Orajel, when your dentist gave you that dental injection, it still hurt seriously. I’m sure you’ve been thinking in your head, did that numbing gel do anything at all?! If the Orajel really numbed your tooth, that hypodermic needle shouldn’t hurt at all, right? So yeah, basically the gel doesn’t numb you enough to not feel pain through the needle.

Last but not the least, if you were going to have a cavity filling and your dentist only uses Orajel, you would feel great pain as soon as he starts drilling. You NEED that second numbing shot to completely numb the tooth. The Orajel is NOT enough to completely numb a tooth!

Why doesn’t Orajel completely numb the tooth?

The reason why Orajel is not very effective for numbing the tooth is because the gel is not able to penetrate the surface of the tooth to reach the nerve of the tooth. For this reason, the product is labeled as a “topical” anesthetic. The label topical means that it only works on the surface and not beyond. This means if you have nerve pain coming from inside the tooth, applying the gel to the surface won’t do anything for the pain as it can’t get inside the tooth!

The novocaine or lidocaine that your dentist uses to completely numb your tooth is not a local anesthetic, but a “local anesthetic.” This means that it works in a localized area and is not just limited to surface effects like the topical anesthetics.

What is JUDGMENT?

Basically, the effect of Orajel only lasts up to 20 minutes, but it is not very effective at first. It is not able to completely numb the tooth because the gel is unable to penetrate through the tooth and into the nerve to numb it. It will provide a tiny bit of relief at most, but only for a mild toothache, and it will only last 20 minutes.

If you use an Orajel product, we recommend skipping the original and the 3X and going straight for the Orajel 4X. Based on our research above, even the 4X won’t give you the pain relief you want if you have a severe toothache, so there’s essentially no point in using the weaker Orajel products.

However, if you really need toothache relief, you should see a dentist instead because we are experts in toothache relief.

Lip fillers are injections that give the lips a plumper and fuller appearance. They are commonly referred to as dermal fillers. Four types of dermal fillers approved by the Food and Drug Administration (FDA) are: Hyaluronic acid

calcium hydroxyapatite

Poly-L-lactic acid (PLLA)

Polymethyl methacrylate (PMMA) beads suspended in bovine (cow) collagen. Sometimes estheticians use lip botox for a similar effect, but this is not considered a dermal filler. The lip filler procedure only takes a few minutes and is minimally invasive. But the procedure isn’t permanent, and you’ll need future injections to maintain the lip fullness that the filler creates. You may experience swelling or tenderness and bruising after the procedure, although side effects should be minor. Aftercare for lip fillers is manageable. If you’re unsure if the procedure is right for you, it helps to be clear about what to expect during follow-up.

10 Lip Plumper Care Tips If you have bruising at the injection site, applying aloe vera, vitamin K, or arnica creams may help, according to a 2015 review. It’s a good idea to speak to your doctor before using these. After that, apply ice to your lips using an ice pack or an ice cube covered with a thin cloth (so it doesn’t stick to the lip and cause pain). This helps reduce swelling, itching, bruising, and other pain. Avoid strenuous exercise for 24 to 48 hours after receiving lip or other dermal fillers. Elevated blood pressure and heart rate from exercise can make swelling or bruising worse. Light activities like walking are fine. drink enough Drinking plenty of water helps your body heal. Eat plenty of hydrating fruits and vegetables and try to avoid excess sodium, which can make swelling worse. Avoid high temperatures such as steam rooms, saunas or heated exercise classes for 48 hours after treatment. High heat can increase swelling. Ask your doctor what pain relievers you can take in the days following your treatment. Tylenol is usually fine, but no blood-thinning medications like ibuprofen or aspirin. If you are getting lip fillers for a specific event, make sure you allow enough time between the procedure and the event to allow your lips to properly recover. Try sleeping with your head elevated on pillows to reduce swelling. Don’t sleep on your face. Avoid putting makeup on your lips for up to 24 hours after the procedure.

Things to Avoid During Lip Puffing Follow-Up Here are a few other things your doctor will likely recommend avoiding after your lip plumping procedure. Avoid Alcohol Alcohol thins blood, so you should avoid it for at least 24 hours after having lip fillers. Alcohol can also cause inflammation, increase the chance of bruising, and make swelling worse. It’s also a good idea to abstain from alcohol a few days before your appointment. Don’t fly Your doctor will probably recommend that you wait at least a week after your treatment before flying. This is because the air pressure in an airplane can make swelling and bruising worse.

When will it reach the final look? With lip fillers, you’ll see results right away, but once the swelling has gone down, the results don’t look as pronounced. It usually takes about 4 weeks for the filler to settle in and achieve the final, desired look. The results usually last about 6 months.

Side effects of lip fillers Side effects of lip fillers can occur within hours, days, or weeks of receiving the injections. According to the FDA, they usually go away within a short period of time, but can occasionally appear weeks, months, or years later. These side effects include: bruising

itching

swelling

pain and tenderness

redness

Rash In some cases, more serious complications can occur. In these cases you should consult a doctor. Read more below.

When to See a Doctor While minor side effects like swelling and redness are normal, see a doctor if you notice any of the following complications. Excessive bruising or swelling If you have excessive bruising or swelling for more than a week, call your doctor. It’s rare, but allergies and reactions are possible. Vascular occlusion occurs when the filler is injected into or around an artery, reducing or stopping blood flow. The surrounding skin and tissues begin to die without an adequate blood supply. Signs of vascular occlusion include immediate, severe pain and a change in skin color that may look like white patches or patches. It’s also important to note that since most fillers contain lidocaine, which is an anesthetic, it can take a while for the pain to be noticeable. It may take several hours to wear off after the injection process. Lumps In one case study, a woman injected with bovine collagen developed hard swellings at the injection sites. Clumping, nodules, and bumps can also occur with other types of fillers. Lumps caused by the most common type of lip filler, hyaluronic acid, can be broken up with a drug called hyaluronidase. But many lumps of this filler will simply improve with massage and time. When lumps are caused by inflammation, medical professionals can treat them with corticosteroid injections, and they appear to go away in some cases, but not all. Lumps and bumps caused by dermal fillers can often be surgically removed if they don’t go away on their own. Cold sores Your doctor will ask you if you are prone to cold sores or herpes simplex virus 1 (HSV-1). Dermal fillers can trigger an outbreak that may require antiviral treatment. It’s best to talk to your doctor if you’ve had a history of herpes outbreaks after getting dermal fillers.

Based on your description, it is quite possible that you are sensitive to the anesthetic used in your treatment. I would suggest seeing a dermatologist who will do patch testing to determine what you may be sensitive/allergic to. I have seen several cases of patients in my clinic reacting to numbing creams, particularly compound formulations. I have seen a few cases of people having unusual swelling and redness after being treated with Vivace. Patch testing in these cases has revealed the causes – whether it be ingredients in the numbing cream vehicle or the actual numbing agent itself. If you know what you are allergic to you can tell your Vivace practitioner to discuss options for different numbing/ discuss anesthesia options.

lidocaine topical

Generic Name: Lidocaine Topical [LYE-doe-kane-TOP-i-kal]

Brand names: AneCream, Bactine, Glydo, LidaMantle, Lidoderm, … show all 11 brands LidoRx, Medi-Quik Spray, RadiaGuard, RectiCare, Regenecare HA Spray, Solarcaine Cool Aloe

Dosage forms: intradermal device (0.5 mg); topical cream (3%; 4%; 5%); topical film (1.8%; 3.5%; 4%; 5%); topical gel (0.5%; 2.8%; 3%; 4%); topical gel with applicator (2%); topical kit (4%; 5%; 5% with emollients); topical liquid (2.5%); topical lotion (1%); topical ointment (5%); topical solution (4%); topical spray (0.5%; 10%; 2%; 4%)

Drug class: local anesthetics

Medically reviewed by Drugs.com on May 17, 2022. Written by Cerner Multum.

What is lidocaine topical?

Lidocaine is a local anesthetic (numbing drug). There are many brands and forms of lidocaine. Not all brands are listed in this brochure.

Topical lidocaine (for application to the skin) is used to relieve pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison oak, and minor cuts, scrapes, or burns. Lidocaine topical is also used to treat rectal discomfort caused by hemorrhoids.

The intradermal lidocaine device can be used during minor medical procedures such as venipuncture or peripheral intravenous cannulation.

Lidocaine topical may also be used for purposes not listed in this medication guide.

warnings

An overdose of numbing drugs can have deadly side effects if too much of the drug is absorbed through the skin.

Do not use large amounts of lidocaine topically, and do not cover the treated skin areas with a bandage or plastic wrap without medical advice.

Keep both used and unused lidocaine skin patches out of the reach of children and pets. The amount of lidocaine in the skin patches could be harmful to a child or pet who accidentally sucks or swallows the patch.

Before taking this medicine

You should not use lidocaine topically if you are allergic to any type of narcotic.

Fatal overdoses have occurred when numbing drugs are used without a doctor’s advice (eg, during a cosmetic procedure such as laser hair removal). However, overdose has also occurred in women treated with an anesthetic drug prior to mammography.

Note that many cosmetic procedures are performed without the presence of a doctor.

Tell your doctor if you have ever had:

a blood cell disorder called methemoglobinemia (in you or a family member);

liver disease; or

if you are taking heart rhythm medication.

Tell your doctor if you are pregnant or breastfeeding.

When applying lidocaine topically to your breast, avoid areas that may come into contact with the baby’s mouth.

How should I apply lidocaine topically?

Use topical lidocaine exactly as directed on the label or as directed by your doctor. Do not use this medicine in larger amounts than recommended.

Improper use of lidocaine topical can result in death.

Topical lidocaine comes in many different forms (gel, spray, cream, lotion, ointment, liquid, skin patch, and others).

Do not take orally. Topical medicine is intended for use on the skin only. If this medicine gets in your eyes, nose, mouth, rectum, or vagina, flush with water.

Read and carefully follow all instructions for use that come with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Use the smallest amount of medicine needed to numb the skin or relieve pain. Your body can absorb too much of this medicine if you use too much of it, if you apply it to large areas of skin, or if you apply heat, bandages, or plastic wrap to treated areas of skin. Skin that’s cut or irritated can also absorb more topical medications than healthy skin.

Do not use this medicine on swollen areas of skin or deep puncture wounds. Avoid using the medicine on rough or blistered skin, such as B. severe burns or abrasions.

Do not cover the treated skin unless instructed to do so by your doctor.

Lidocaine topical can be applied with your fingertips or a cotton swab.

The lidocaine intradermal device is applied by a healthcare provider.

Store at room temperature away from moisture and heat.

Keep both used and unused lidocaine topical skin patches out of the reach of children or pets. The amount of lidocaine in the skin patches could be harmful to a child or pet who accidentally sucks or swallows the patch. In this case, seek emergency medical attention.

What happens if I miss a dose?

Because lidocaine is used topically when needed, you may not have a dosing schedule. Skip any missed dose if it is almost time for your next dose. Do not use two cans at the same time.

What happens if I overdose?

See an ambulance or call the poison control center at 1-800-222-1222. An overdose of a numbing drug can have fatal side effects if too much of the drug is absorbed through your skin and into your blood.

Symptoms of overdose may include an irregular heartbeat, seizures (convulsions), slow breathing, coma, or failure to breathe (pauses in breathing).

Lidocaine applied to the skin is unlikely to cause an overdose unless you apply more than the recommended dose.

What should I avoid when using lidocaine topically?

Avoid touching the sticky side of a lidocaine skin patch while applying it.

Avoid accidentally injuring treated skin areas while they are numb. Avoid contact with very hot or very cold surfaces.

Topical side effects of lidocaine

Get medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of the face, lips, tongue or throat.

Topical lidocaine can cause serious side effects. Call your doctor at once if you have:

severe headache or vomiting;

severe burning, stinging or irritation where the medicine was applied;

swelling or redness;

sudden dizziness or drowsiness after using medication;

confusion, speech or vision problems, ringing in the ears; or

unusual temperature sensations.

Common side effects are:

slight irritation where the drug is applied; or

Numbness in places where the medicine was accidentally applied.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

What Other Medications Affect Topical Lidocaine?

Medicines used on the skin are unlikely to be affected by other medicines you are using. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Always check with your doctor to ensure that the information presented on this page is appropriate for your personal circumstances.

Medical Disclaimer

Copyright 1996-2022 Cerner Multum, Inc. Version: 9.02.

A doctor or nurse will usually write you a prescription for lidocaine cream or the cream itself before your appointment. Always follow the directions that come with your cream.

If you are having an IV drip or blood drawn, apply the lidocaine cream 1 hour before.

For minor procedures, your doctor may tell you to apply the cream more than 1 hour before the procedure.

If the procedure is delayed and the numbing effect of the cream has worn off, ask your doctor or nurse for advice before applying any more creams.

If you are having a cosmetic procedure and purchased lidocaine from a pharmacy to numb the area, let the person performing the procedure know before it begins. It will help them know the area has been numbed and you will feel less pain.

How much to use

The amount you use depends on the procedure you have and the type of lidocaine cream you use.

Read the instructions that come with the cream or follow the advice of your doctor or nurse.

They may tell you to apply an entire tube of cream to each area of ​​your skin, more than one tube, or just part of a tube.

How to put it on

Published: July 14, 2017 in: Skin diseases

A tattoo, bikini wax or laser hair removal need not cause you pain. In fact, more and more people are using numbing creams to take the sting out of painful skin treatments.

Numbing cream is a formula that contains an anesthetic and can be applied directly to the skin to relieve pain symptoms. When applied before skin treatments, waxing, or tattooing, it numbs the area and provides fast pain relief.

Numbing Cream can be used for:

injections and blood samples

dermal fillers

Laser hair removal

Permanent makeup

piercing

skin treatments

tattoo

To grow

How does numbing cream work?

Numbing cream prevents the pain signals from reaching the brain because ingredients contain active narcotics. It acts as an anesthetic to numb a selected area before a skin treatment.

How long does the numbing cream last?

A numbing cream should be applied approximately 30 minutes to an hour before the skin treatment in question and your skin will remain numb for up to two hours after application.

Best UK Numbing Creams

So which numbing cream is best for you? Two of the best numbing creams on the market are EMLA numbing cream and LMX4 numbing cream. LMX numbing cream contains the active ingredient lidocaine, while Ametop numbing cream contains tetracaine; both are known to quickly relieve pain. LMX4 Numbing Cream can also be used to relieve the pain of insect bites, minor cuts and burns and abrasions, and before skin treatments such as medicated facial peels, permanent makeup and dermal fillers.

Where to buy numbing cream

You don’t need a prescription to buy the leading brands of numbing creams. If you are looking for an effective numbing cream you can shop online at Weldricks and buy both Ametop numbing cream and LMX4 numbing cream. Alternatively, you can buy numbing creams from your pharmacy without a prescription.

So there you have everything you ever wanted to know about numbing cream. Browse through our extensive range of numbing creams online at your leisure.

Lip fillers are injections that give the lips a plumper and fuller appearance. They are commonly referred to as dermal fillers. Four types of dermal fillers approved by the Food and Drug Administration (FDA) are: Hyaluronic acid

calcium hydroxyapatite

Poly-L-lactic acid (PLLA)

Polymethyl methacrylate (PMMA) beads suspended in bovine (cow) collagen. Sometimes estheticians use lip botox for a similar effect, but this is not considered a dermal filler. The lip filler procedure only takes a few minutes and is minimally invasive. But the procedure isn’t permanent, and you’ll need future injections to maintain the lip fullness that the filler creates. You may experience swelling or tenderness and bruising after the procedure, although side effects should be minor. Aftercare for lip fillers is manageable. If you’re unsure if the procedure is right for you, it helps to be clear about what to expect during follow-up.

10 Lip Plumper Care Tips If you have bruising at the injection site, applying aloe vera, vitamin K, or arnica creams may help, according to a 2015 review. It’s a good idea to speak to your doctor before using these. After that, apply ice to your lips using an ice pack or an ice cube covered with a thin cloth (so it doesn’t stick to the lip and cause pain). This helps reduce swelling, itching, bruising, and other pain. Avoid strenuous exercise for 24 to 48 hours after receiving lip or other dermal fillers. Elevated blood pressure and heart rate from exercise can make swelling or bruising worse. Light activities like walking are fine. drink enough Drinking plenty of water helps your body heal. Eat plenty of hydrating fruits and vegetables and try to avoid excess sodium, which can make swelling worse. Avoid high temperatures such as steam rooms, saunas or heated exercise classes for 48 hours after treatment. High heat can increase swelling. Ask your doctor what pain relievers you can take in the days following your treatment. Tylenol is usually fine, but no blood-thinning medications like ibuprofen or aspirin. If you are getting lip fillers for a specific event, make sure you allow enough time between the procedure and the event to allow your lips to properly recover. Try sleeping with your head elevated on pillows to reduce swelling. Don’t sleep on your face. Avoid putting makeup on your lips for up to 24 hours after the procedure.

Things to Avoid During Lip Puffing Follow-Up Here are a few other things your doctor will likely recommend avoiding after your lip plumping procedure. Avoid Alcohol Alcohol thins blood, so you should avoid it for at least 24 hours after having lip fillers. Alcohol can also cause inflammation, increase the chance of bruising, and make swelling worse. It’s also a good idea to abstain from alcohol a few days before your appointment. Don’t fly Your doctor will probably recommend that you wait at least a week after your treatment before flying. This is because the air pressure in an airplane can make swelling and bruising worse.

When will it reach the final look? With lip fillers, you’ll see results right away, but once the swelling has gone down, the results don’t look as pronounced. It usually takes about 4 weeks for the filler to settle in and achieve the final, desired look. The results usually last about 6 months.

Side effects of lip fillers Side effects of lip fillers can occur within hours, days, or weeks of receiving the injections. According to the FDA, they usually go away within a short period of time, but can occasionally appear weeks, months, or years later. These side effects include: bruising

itching

swelling

pain and tenderness

redness

Rash In some cases, more serious complications can occur. In these cases you should consult a doctor. Read more below.

When to See a Doctor While minor side effects like swelling and redness are normal, see a doctor if you notice any of the following complications. Excessive bruising or swelling If you have excessive bruising or swelling for more than a week, call your doctor. It’s rare, but allergies and reactions are possible. Vascular occlusion occurs when the filler is injected into or around an artery, reducing or stopping blood flow. The surrounding skin and tissues begin to die without an adequate blood supply. Signs of vascular occlusion include immediate, severe pain and a change in skin color that may look like white patches or patches. It’s also important to note that since most fillers contain lidocaine, which is an anesthetic, it can take a while for the pain to be noticeable. It may take several hours to wear off after the injection process. Lumps In one case study, a woman injected with bovine collagen developed hard swellings at the injection sites. Clumping, nodules, and bumps can also occur with other types of fillers. Lumps caused by the most common type of lip filler, hyaluronic acid, can be broken up with a drug called hyaluronidase. But many lumps of this filler will simply improve with massage and time. When lumps are caused by inflammation, medical professionals can treat them with corticosteroid injections, and they appear to go away in some cases, but not all. Lumps and bumps caused by dermal fillers can often be surgically removed if they don’t go away on their own. Cold sores Your doctor will ask you if you are prone to cold sores or herpes simplex virus 1 (HSV-1). Dermal fillers can trigger an outbreak that may require antiviral treatment. It’s best to talk to your doctor if you’ve had a history of herpes outbreaks after getting dermal fillers.