Black Seed Oil Vs Oil Of Oregano? The 57 New Answer

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It is well known that Oil of Wild Oregano possesses a powerful & therapeutic active ingredient, Carvacrol. Similarly, Black Seed Oil possesses the powerful active ingredient, Thymoquinone. Oil of Wild Oregano is one of the most powerful, potent essential oils.Children and pregnant or lactating individuals should not take black seed oil. Certain drugs, herbs, and supplements can have interactions. 4 Always consult your healthcare provider before starting a supplement.Because of its ability to protect against bacterial infection, topical oregano oil has been shown to be effective in wound treatment and healing, even killing off methicillin-resistant Staphylococcus aureus (MRSA). In addition to being a powerful antimicrobial agent, oregano oil also has anti-inflammatory effects.

Who should not take black seed oil?

Children and pregnant or lactating individuals should not take black seed oil. Certain drugs, herbs, and supplements can have interactions. 4 Always consult your healthcare provider before starting a supplement.

What does oregano oil cure?

Because of its ability to protect against bacterial infection, topical oregano oil has been shown to be effective in wound treatment and healing, even killing off methicillin-resistant Staphylococcus aureus (MRSA). In addition to being a powerful antimicrobial agent, oregano oil also has anti-inflammatory effects.

Is black seed oil powerful?

Black seed oil is a powerful herbal ingredient associated with a variety of health and beauty benefits. In particular, it may ease inflammation, lower blood sugar levels, improve skin and hair health, and help you manage your weight.

When should you not take oil of oregano?

Remember that essential oils are much stronger than the supplements and should always be diluted. Oregano oils shouldn’t be used in babies or children, and pregnant or breastfeeding women. Baser KH. (2008).

Oregano Oil: Is It Good for You?

Overview You may already know that oregano is an Italian herb commonly used in cooking. However, it can also be made into a more concentrated herbal supplement, often referred to as oregano oil. There are also oregano essential oils that have a much stronger concentration of the oregano plant than the herbal supplement. Oregano essential oil is extracted from the leaves of the oregano plant. Although oregano is a well-known herb found in many kitchens, oregano herb oils and oregano essential oils are not used in cooking. Rather, the essential oil is used both topically and through inhalation to treat certain health conditions. The herbal oil can be taken as an herbal supplement. Oregano oil contains chemical compounds including phenolic glycosides (phenols). These compounds have antioxidant and antimicrobial properties. Phenols such as carvacrol, cymene, terpinine and thymol make up a majority of the composition of oregano oil. It’s the phenols in oregano oil that can make it beneficial.

Side Effects and Risks Unlike the herb you cook with, commercially prepared oregano oil is highly concentrated. It’s easy to take too much or use it for too long. When used as directed, oregano oil should be safe. In too high doses it can have harmful effects. This may be due in part to thymol, one of the phenols it contains. In high doses, thymol is a mild irritant that can affect the skin or internal organs. It can cause: nausea

Vomit

upset stomach

central hyperactivity (inappropriate talkativeness) Thymol can also irritate or corrode the skin and eyes. Oregano oil should never be applied to broken skin or used on or near the eyes. Oregano oil can cause allergic reactions in some people. If you are allergic to oregano or other plants in the mint family such as mint, sage, basil, and lavender, do not use oregano oil. When applied topically, diluted oregano essential oil can cause a rash, even in people who are not allergic to it. It’s important to consult your doctor before using oregano oil and follow package directions carefully, whether you’re using the capsules or the essential oil. No medical research has been conducted on the safety of oregano oil for children or for pregnant or breastfeeding women. These populations should not use oregano oil. Although data is lacking, there is some concern that oregano oil may cause uterine contractions or miscarriage.

Guidelines for Proper Dosage and Use Medicinal dosages of oregano oil for humans have not been extensively studied. Commercially sold dietary supplements and essential oils have recommended dosages set by their manufacturers. These take into account the amount of thymol and other phenols. It is important not to exceed the recommended dosage or take oregano oil in any form, including on the skin, for more than several weeks. When using oregano essential oil, a little goes a long way. A drop or two of diluted oil may not seem like much, but exceeding this dosage can lead to side effects.

When to See Your Doctor Symptoms of an oregano allergy may include a rash, stomach upset, or difficulty breathing. It’s especially important not to inhale oregano oil if you may be allergic to it. This can lead to inflammation of the airways and can quickly become dangerous. Chronic exposure to thymol can cause symptoms that warrant a doctor’s visit. These include: Fatigue

Diarrhea

Muscle aches

dizziness

headache

difficulties swallowing

excessive salivation

What are the dangers of black seed oil?

Black seed can cause allergic rashes in some people. It can also cause stomach upset, vomiting, or constipation. When applied to the skin: Black seed oil or gel is possibly safe when used short-term. It can cause allergic rashes in some people.

Oregano Oil: Is It Good for You?

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El Obeid, A., Al Harbi, S., Al Jomah, N., and Hassib, A. Plant melanin modulates tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), and vascular endothelial growth factor (VEGF). ) production. phytomedicine. 2006;13(5):324-333. View summary.

El Saleh, S.C., Al Sagair, O.A., and Al Khalaf, MI. Protection of thymoquinone and Nigella sativa oil against methionine-induced hyperhomocysteinemia in rats. international J.Cardiol. 2004;93(1):19-23. View summary.

el Tahir, KE, Ashour, MM, and al Harbi, MM. The cardiovascular effects of black cumin (Nigella sativa) essential oil in rats: elucidating the mechanism of action. Gen. Pharmacol. 1993;24(5):1123-1131. View summary.

El Wakil, S. S. Evaluation of the in vitro effect of aqueous Nigella sativa extract on Blastocystis hominis isolates. J Egypt Soc.Parasitol. 2007;37(3):801-813. View summary.

El-Gharieb MA and et al. Possible hepatoprotective effects of vitamin E and Nigella sativa oil on hepatotoxicity induced by chronic malathion exposure in human and male albino rats. Toxicological & Environmental Chemistry. 2010;92(2):395-412.

Enomoto, S., Asano, R., Iwahori, Y., Narui, T., Okada, Y., Singab, AN., and Okuyama, T. Hematological studies on black seed oil from the seeds of Nigella sativa L. Biol. Pharm.Bull 2001;24(3):307-310. View summary.

Fararh, KM, Atoji, Y, Shimizu, Y, Shiina, T, Nikami, H, and Takewaki, T. Mechanisms of the hypoglycemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters. Res Vet. Sci 2004;77(2):123-129. View summary.

KM Fararh, AK Ibrahim and YA Elsonosy. Res Vet. Sci 2010;88(3):400-404. View summary.

Fararh KM, Shimizu Y, Shiina T, Nikami H, Ghanem MM, and Takewaki T. Res Vet. Sci 2005;79(3):219-223. View summary.

Fouda, A.M., Daba, M.H., Dahab, G.M. and Sharaf El-Din, O.A. Basic Clinic Pharmacol. Toxicol. 2008;103(2):109-118. View summary.

Gali-Muhtasib, H., Diab-Assaf, M., Boltze, C., Al Hmaira, J., Hartig, R., Roessner, A., and Schneider-Stock, R. Thymoquinone extracted from black cumin seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. international J Oncol. 2004;25(4):857-866. View summary.

Gali-Muhtasib, H., Roessner, A., and Schneider-Stock, R. Thymoquinone: a promising anticancer drug from natural sources. Int J Biochem CellBiol. 2006;38(8):1249-1253. View summary.

Ghannadi, A., Hajhashemi, V., and Jafarabadi, H. A study of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols. J Med Food 2005;8(4):488-493. View summary.

Hansen, J. T., Benghuzzi, H., Tucci, M., and Cason, Z. The role of black seed in proliferation and biochemical marker levels of Hep-2 cells. Biomed.Sci.Instrum. 2003;39:371-376. View summary.

Hawsawi, ZA, Ali, BA, and Bamosa, A. O. Effect of Nigella sativa (black seed) and thymoquinone on blood glucose in albino rats. Ann. Saudi Med 2001;21(3-4):242-244. View summary.

Hosseinzadeh, H. and Parvardeh, S. Anticonvulsant effects of thymoquinone, the main component of Nigella sativa seeds, in mice. Phytomedicine 2004;11(1):56-64. View summary.

Hosseinzadeh, H., Parvardeh, S., Nassiri-Asl, M., and Mansouri, MT. Intracerebroventricular administration of thymoquinone, the main component of Nigella sativa seeds, suppresses epileptic seizures in rats. Med Sci Monitor. 2005;11(4):BR106-BR110. View summary.

A Ilhan, A Gurel, F Armencu, S Kamisli, and M Iraz. Neuropharmacology 2005;49(4):456-464. View summary.

Islam, S.K., Ahsan, M., Hassan, C.M., and Malek, M.A. Antifungal activities of Nigella sativa seed oils. package J Pharm Sci 1989; 2(1): 25-28. View summary.

Islam, S.N., Begum, P., Ahsan, T., Huque, S., and Ahsan, M. Immunosuppressive and cytotoxic properties of Nigella sativa. Phytother.Res. 2004;18(5):395-398. View summary.

Jadayil, S. A., Tukan, S. K., and Takruri, H. R. Bioavailability of iron from four different local food crops in Jordan. Plant-based foods Hum.Nutr. 1999;54(4):285-294. View summary.

Kaleem, M., Kirmani, D., Asif, M., Ahmed, Q., and Bano, B. Biochemical effects of Nigella sativa L seeds in diabetic rats. Indian J Exp. Biol. 2006;44(9):745-748. View summary.

Kalus, U., Pruss, A., Bystron, J., Jurecka, M., Smekalova, A., Lichius, J.J., and Kiesewetter, H. Effect of Nigella sativa (black cumin) on subjective feeling in patients with allergic diseases. Phytother.Res. 2003;17(10):1209-1214. View summary.

Kamal EH and et al. Some cardiovascular effects of the dethymoquinones essential oil Nigella sativa and its main components alpha-pinene and p-cymene in rats. Saudi Pharmaceutical Journal (Saudi Arabia). 2003;11:104-110.

Kanter, M. Effects of Nigella sativa and its main component thymoquinone on sciatic nerves in experimental diabetic neuropathy. Neurochem. Res 2008;33(1):87-96. View summary.

Kanter, M. Effects of Nigella sativa seed extract on amelioration of lung tissue damage in rats after experimental lung aspiration. Acta Histochem. 2009;111(5):393-403. View summary.

Kanter, M. Protective effect of thymoquinone on streptozotocin-induced diabetic nephropathy. J Mol.Histol. 2009;40(2):107-115. View summary.

Kanter, M., Coskun, O., and Uysal, H. The antioxidant and antihistaminic effects of Nigella sativa and its major component thymoquinone on ethanol-induced gastric mucosal damage. Arch Toxicol. 2006;80(4):217-224. View summary.

Kanter, M., Coskun, O., Korkmaz, A., and Oter, S. Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozotocin-induced diabetic rats. Anat.Rec.A Discov.Mol.Cell Evol.Biol. 2004;279(1):685-691. View summary.

Kanter, M., Demir, H., Karakaya, C., and Ozbek, H. Gastroprotective activity of Nigella sativa L-oil and its component thymoquinone against acute alcohol-induced gastric mucosal injury in rats. World J Gastroenterol. 2005-11-14;11(42):6662-6666. View summary.

Kanter, M., Meral, I., Yener, Z., Ozbek, H., and Demir, H. Partial regeneration/proliferation of beta cells in the islets of Langerhans by Nigella sativa L. in streptozotocin-induced diabetic rats. Tohoku J Exp.Med 2003;201(4):213-219. View summary.

Keyhanmanesh, R., Boskabady, M. H., Eslamizadeh, M. J., Khamneh, S., and Ebrahimi, MA. The effect of thymoquinone, the main component of Nigella sativa, on tracheal sensitivity and white blood cell count in the lung lavage of sensitized guinea pigs. Planta Med 2010;76(3):218-222. View summary.

Kocyigit, Y., Atamer, Y., and Uysal, E. The effect of Nigella sativa L. dietary supplementation on serum lipid profile in rats. Saudi Med J 2009;30(7):893-896. View summary.

Kooshki A, Forouzan R, Rakhshani MH, Mohammadi M. Effect of topical application of Nigella sativa oil and oral acetaminophen on pain in elderly people with knee osteoarthritis: a crossover clinical study. electron doctor. Nov 25, 2016; 8(11):3193-97. View summary.

Kooshki A, Tofighiyan T, Rastgoo N, Rakhshani MH, Miri M. Effect of Nigella sativa oil supplement on cardiovascular disease risk factors in patients with type 2 diabetes mellitus. Phytother Res. 2020. View summary.

Koshak A, Wei L, Koshak E, et al. Nigella sativa supplementation improves asthma control and biomarkers: a randomized, double-blind, placebo-controlled study. Phytother Res. 2017 Mar;31(3):403-9. View summary.

Mahdavi R, Namazi N, Alizadeh M, Farajnia S. Effects of Nigella sativa oil with a calorie restricted diet on cardiometabolic risk factors in obese women: a randomized controlled clinical trial. Food Function 2015;6(6):2041-8. View summary.

Medenica RD. Using black seed to boost immune function. U.S. Patent 5,482,711 Issued January 9, 1996. Obtained from US Patent and Trademark Ofc on April 12, 2000. www.uspto.gov/patft/index.htm.

Mohtashami A, Mahaki B, Azadbakht L, Entezari MH. Effects of bread containing Nigella sativa on lipid profiles, apolipoproteins and inflammatory factors in patients with metabolic syndrome. Clin Nutr Res. 2016;5(2):89-95. View summary.

Mohtashami R, Huseini HF, Heydari M, et al. Efficacy and safety of a honey-based formulation of Nigella sativa seed oil in functional dyspepsia: A double-blind, randomized, controlled clinical trial. J Ethnopharmacol 2015;175:147-52. View summary.

Molaie M, Darvishi B, Jafari Azar Z, Shirazi M, Amin G, Afshar S. Effects of a combination of Nigella sativa and Vitex agnus-castus with citalopram on healthy menopausal women with hot flashes: results of a subpopulation analysis. Gynecol Endocrinol. 2019 Jan;35(1):58-61. View summary.

Mousa HFM, Abd-El-Fatah NK, Darwish OA, Shehata SF, Fadel SH. Effect of Nigella sativa seed administration on the prevention of febrile neutropenia during chemotherapy in children with brain tumors. Child’s nerve syst. 2017;33(5):793-800. View summary.

Mousavi SM, Sheikhi A, Varkaneh HK, Zarezadeh M, Rahmani J, Milajerdi A. Effect of Nigella sativa supplementation on obesity indices: A systematic review and meta-analysis of randomized controlled trials. Supplement Ther Med. 2018;38:48-57. View summary.

Moustafa HAM, El Wakeel LM, Halawa MR, Sabri NA, El-Bahy AZ, Singab AN. Effect of Nigella sativa oil compared to metformin on glycemic control and biochemical parameters in patients with newly diagnosed type 2 diabetes mellitus. Endocrine 2019;65(2):286-94. View summary.

Muneera KE, Majeed A, Naveed AK. Vergleichende Bewertung von Nigella sativa (Kalonji) und Simvastatin zur Behandlung von Hyperlipidämie und zur Induktion von Hepatotoxizität. Pak J. Pharm. Sci. 2015 März;28(2):493-8. View summary.

Nagi MN, Alam K., Badary OA, et al. Thymochinon schützt bei Mäusen über einen antioxidativen Mechanismus vor Tetrachlorkohlenstoff-Hepatotoxizität. biochem. Mol. Biol. Int. 1999;47:153-9. View summary.

Namazi N, Larijani B, Ayati MH, Abdollahi M. Die Auswirkungen von Nigella sativa L. auf Fettleibigkeit: eine systematische Überprüfung und Metaanalyse. J Ethnopharmacol 2018;219:173-81. doi: 10.1016/j.jep.2018.03.001. View summary.

Nikakhlagh S, Rahim F, Aryani FH, Syahpoush A, Brougerdnya MG, Saki N. Pflanzliche Behandlung von allergischer Rhinitis: die Verwendung von Nigella sativa. Bin J Otolaryngol. 2011 Sep.-Okt.;32(5):402-7. View summary.

Nikkhah-Bodaghi M, Darabi Z, Agah S, Hekmatdoost A. Die Auswirkungen von Nigella sativa auf die Lebensqualität, den Krankheitsaktivitätsindex und einige entzündliche und oxidative Stressfaktoren bei Patienten mit Colitis ulcerosa. Phytother Res. 2019 Apr;33(4):1027-1032. doi: 10.1002/ptr.6296. Epub 2019, 22. Januar. Zusammenfassung anzeigen.

Onifade AA, Jewell AP, Adedeji WA. Nigella sativa concoction induced sustained seroreversion in HIV patient. Afr J Tradit Complement Altern Med. 2013;10(5):332-5. View summary.

Oysu C, Tosun A, Yilmaz HB, Sahin-Yilmaz A, Korkmaz D, Karaaslan A. Topical nigella sativa for nasal symptoms in elderly. Auris Nasus Larynx. 2014 Jun;41(3):269-72. View summary.

Perveen T, Haider S, Zuberi NA, et al. Increased 5-HT levels following repeated administration of Nigella sativa L. (Black Seed) oil produce antidepressant effects in rats. Sci Pharm 2013;82:161-70. View summary.

Rafati M, Ghasemi A, Saeedi M, et al. Nigella sativa L. for prevention of acute radiation dermatitis in breast cancer: A randomized, double-blind, placebo-controlled, clinical trial. Complement Ther Med. 2019;47:102205. View summary.

Razmpoosh E, Safi S, Abdollahi N, et al. The effect of Nigella sativa on the measures of liver and kidney parameters: A systematic review and meta-analysis of randomized-controlled trials. pharmacol. Res. 2020;156:104767. View summary.

Razmpoosh E, Safi S, Nadjarzadeh A, et al. The effect of Nigella sativa supplementation on cardiovascular risk factors in obese and overweight women: a crossover, double-blind, placebo-controlled randomized clinical trial. Eur J Nutr. 2020. View summary.

Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, et al. Clinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trial. Medicinski Arhiv 2012;66(3):198-200. View summary.

Safi S, Razmpoosh E, Fallahzadeh H, et al. The effect of Nigella sativa on appetite, anthropometric and body composition indices among overweight and obese women: A crossover, double-blind, placebo-controlled, randomized clinical trial. Complement Ther Med. 2020;57:102653. View summary.

Sahebkar A, Soranna D, Liu X, et al. A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure. J Hypertens 2016;34:2127-35. View summary.

Salem AM, Bamosa AO, Qutub HO, et al. Effect of Nigella sativa supplementation on lung function and inflammatory mediatorsin partly controlled asthma: a randomized controlled trial. Ann Saudi Med 2017;37:64-71. View summary.

Salem EM, Yar T, Bamosa AO, et al. Comparative study of nigella sativa and triple therapy in eradication of helicobacter pylori in patients with non-ulcer dyspepsia. Saudi J Gastroenterol. 2010 Jul-Sep;16(3):207-14. View summary.

Salomi NJ, Nair SC, Jayawardhanan KK, et al. Antitumour principles from Black seed seeds. Cancer Lett 1992;63:41-6. View summary.

Samadipour E, Rakhshani MH, Kooshki A, Amin B. Local usage of Nigella sativa oil as an innovative method to attenuate primary dysmenorrhea: A randomized double-blind clinical trial. Oman Med J. 2020;35(5):e167. View summary.

Sarac G, Kapicioglu Y, Sener S, et al. Effectiveness of topical Nigella sativa for vitiligo treatment. Dermatol Ther 2019;32(4):e12949. View summary.

Shawki M, El Wakeel L, Shatla R, et al. The clinical outcome of adjuvant therapy with black seed oil on intractable paediatric seizures: a pilot study. Epileptic Disord 2013;15:295-301. View summary.

Shirazi M, Khodakarami F, Feizabad E, Ghaemi M. The effects of nigella sativa on anthropometric and biochemical indices in postmenopausal women with metabolic syndrome. Endocrine. 2020;69(1):49-52. View summary.

Singh V, Gupta A, Verma UP, Mishra T, Pal M. An evaluation of the efficacy of ethanolic extract of Nigella sativa L. (Kalonji) on the clinical parameters of moderate to severe gingivitis: A split mouth clinical study. Ayu. 2019;40(3):152-158. View summary.

Soleymani S, Zargaran A, Farzaei MH, et al. The effect of a hydrogel made by Nigella sativa L. on acne vulgaris: A randomized double-blind clinical trial. Phytother Res. 2020. Zusammenfassung ansehen.

Tavakoly R, Arab A, Vallianou N, et al. The effect of Nigella sativa L. supplementation on serum C-reactive protein: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2019;45:149-55. View summary.

Tennekoon KH, Jeevathayaparan S, Kurukulasooriya AP, Karunanayake EH. Possible hepatotoxicity of Nigella sativa seeds and Dregea volubilis leaves. J Ethnopharmacol 1991;31:283-9. View summary.

Tuna HI, Babadag B, Ozkaraman A, Balci Alparslan G. Investigation of the effect of black cumin oil on pain in osteoarthritis geriatric individuals. Complement Ther Clin Pract 2018;31:290-4. doi: 10.1016/j.ctcp.2018.03.013. View summary.

Wang X, Jiang A, Batra V. Severe thrombocytopenia associated with black seed oil and evening primrose oil. Kurus. 2020;12(6):e8390. View summary.

Warner ME, Warner PA, Sprung J, Warner MA. Black seed oil and perioperative serotonin syndrome: A case report. A A Pract. 2019;13(11):420-422. View summary.

Worthen DR, Ghosheh OA, Crooks PA. The in vitro anti-tumor activity of some crude and purified components of blackseed, Black seed L. Anticancer Res 1998;18(3A):1527-32. View summary.

What does black seed cure?

Today, black seed is used for treating digestive tract conditions including gas, colic, diarrhea, dysentery, constipation, and hemorrhoids. It is also used for respiratory conditions including asthma, allergies, cough, bronchitis, emphysema, flu, swine flu, and congestion.

Oregano Oil: Is It Good for You?

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Sethi, G., Ahn, K. S., and Aggarwal, B. B. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis. Mol.Cancer Res 2008;6(6):1059-1070. View summary.

Shafei, M. N., Boskabady, M. H., and Parsaee, H. Effect of aqueous extract from Nigella sativa L. on guinea pig isolated heart. Indian J Exp. Biol. 2005;43(7):635-639. View summary.

Shafi, G., Munshi, A., Hasan, T. N., Alshatwi, A. A., Jyothy, A., and Lei, D. K. Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa. Cancer Cell Int 2009;9:29. View summary.

Shoieb, AM, Elgayyar, M, Dudrick, PS, Bell, JL, and Tithof, PK. In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. international J Oncol. 2003;22(1):107-113. View summary.

Singh BB, Khorsan R, Vinjamury SP, Der-Martirosian C, Kizhakkeveettil A and Anderson TM Herbal treatments of asthma: a systematic review. J Asthma 2007;44(9):685-698. View summary.

Soleimani, H., Ranjbar, A., Baeeri, M., Mohammadirad, A., Khorasani, R., Yasa, N., and Abdollahi, M. Rat Plasma Oxidation Status After Nigella Sativa L. Botanical Treatment in CCL(4)-Treated Rats. Toxicol.Mech.Methods 2008;18(9):725-731. View summary.

Steinmann, A., Schatzle, M., Agathos, M., and Breit, R. Allergic contact dermatitis due to black seed oil (Nigella sativa) after topical application. Contact Dermatitis 1997;36(5):268-269. View summary.

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Suddek, G. M. Thymoquinone-induced relaxation of isolated rat pulmonary artery. J Ethnopharmacol. 2-3-2010;127(2):210-214. View summary.

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Tan, M., Norwood, A., May, M., Tucci, M., and Benghuzzi, H. Effects of (-)epigallocatechin gallate and thymoquinone on proliferation of a PANC-1 cell line in culture. Biomed. Sci Instrument. 2006;42:363-371. View summary.

Tangyuenyongwatana, P. and Gritsanapan, W. A study on artifacts formation in the Thai traditional medicine Prasaplai. Planta Med 2008;74(11):1403-1405. View summary.

Tangyuenyongwatana, P., Kowapradit, J., Opanasopit, P., and Gritsanapan, W. Cellular transport of anti-inflammatory pro-drugs originated from a herbal formulation of Zingiber cassumunar and Nigella sativa. Chin Med 2009;4:19. View summary.

Tardy, F., Benghuzzi, H., and Tucci, M. The role of thymoquinone and epigallocatechin-3-gallate on the viability of mrc-5 fibroblasts in culture – biomed 2009. Biomed.Sci Instrum. 2009;45:42-47. View summary.

Tauseef, Sultan M., Butt, M. S., and Anjum, F. M. Safety assessment of black cumin fixed and essential oil in normal Sprague Dawley rats: Serological and hematological indices. Food Chem.Toxicol. 2009;47(11):2768-2775. View summary.

Tekeoglu, I., Dogan, A., and Demiralp, L. Effects of thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models. Phytother.Res 2006;20(10):869-871. View summary.

Tekeoglu, I., Dogan, A., Ediz, L., Budancamanak, M., and Demirel, A. Effects of thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models. Phytother.Res. 2007;21(9):895-897. View summary.

Thabrew, M. I., Mitry, R. R., Morsy, M. A., and Hughes, R. D. Cytotoxic effects of a decoction of Nigella sativa, Hemidesmus indicus and Smilax glabra on human hepatoma HepG2 cells. life science. 8-5-2005;77(12):1319-1330. View summary.

Toama, M.A., El Alfy, T.S., and El Fatatry, H.M. Antimicrobial activity of Nigella sativa Linneaus seed essential oil. Antimicrob. Agents Chemother. 1974;6(2):225-226. View summary.

Toppozada, H. H., Mazloum, H. A., and el Dakhakhny, M. The antibacterial properties of the Nigella sativa l. seeds. Active principle with some clinical applications. J.Egypt.Med.Assoc. 1965;48:Suppl-202. View summary.

Turkdogan, M. K., Agaoglu, Z., Yener, Z., Sekeroglu, R., Akkan, H. A., and Avci, M. E. The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes. Dtsch.Tierarztl.Wochenschr. 2001;108(2):71-73. View summary.

Turkdogan, M. K., Ozbek, H., Yener, Z., Tuncer, I., Uygan, I., and Ceylan, E. The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats. Phytother.Res 2003;17(8):942-946. View summary.

Uz, E., Bayrak, O., Uz, E., Kaya, A., Bayrak, R., Uz, B., Turgut, F. H., Bavbek, N., Kanbay, M., and Akcay, A. Nigella sativa oil for prevention of chronic cyclosporine nephrotoxicity: an experimental model. Am.J Nephrol. 2008;28(3):517-522. View summary.

Vahdati-Mashhadian, N., Rakhshandeh, H., and Omidi, A. An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice. Pharmazie 2005;60(7):544-547. View summary.

Vance, S. H., Benghuzzi, H., Wilson-Simpson, F., and Tucci, M. Thymoquinone supplementation and its effect on renal tubular epithelial cells in vitro. Biomed. Sci Instrument. 2008;44:477-482. View summary.

Wienkotter, N., Hopner, D., Schutte, U., Bauer, K., Begrow, F., el Dakhakhny, M., and Verspohl, E. J. The effect of nigellone and thymoquinone on inhibiting trachea contraction and mucociliary clearance. Planta Med 2008;74(2):105-108. View summary.

Wilkins, R., Tucci, M., and Benghuzzi, H. Evaluation of raw 264.7 macrophages treated with epigallocatechin-3-gallate and thymoquinone – biomed 2009. Biomed.Sci Instrum. 2009;45:346-351. View summary.

Wilson-Simpson, F., Vance, S., and Benghuzzi, H. Physiological responses of ES-2 ovarian cell line following administration of epigallocatechin-3-gallate (EGCG), thymoquinone (TQ), and selenium (SE). Biomed. Sci Instrument. 2007;43:378-383. View summary.

Womack, K., Anderson, M., Tucci, M., Hamadain, E., and Benghuzzi, H. Evaluation of bioflavonoids as potential chemotherapeutic agents. Biomed. Sci Instrument. 2006;42:464-469. View summary.

Xuan, N. T., Shumilina, E., Qadri, S. M., Gotz, F., and Lang, F. Effect of thymoquinone on mouse dendritic cells. Cell Physiol Biochem. 2010;25(2-3):307-314. View summary.

Yaman, I. and Balikci, E. Protective effects of nigella sativa against gentamicin-induced nephrotoxicity in rats. Exp.Toxicol.Pathol. 2010;62(2):183-190. View summary.

Yar, T., El Hariri, M., El Bahai, M. N., and Bamosa, A. O. Effects of Nigella sativa supplementation for one month on cardiac reserve in rats. Indian J Physiol Pharmacol. 2008;52(2):141-148. View summary.

Yi, T., Cho, S. G., Yi, Z., Pang, X., Rodriguez, M., Wang, Y., Sethi, G., Aggarwal, B. B., and Liu, M. Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways. Mol.Cancer Ther 2008;7(7):1789-1796. View summary.

Yildiz, F., Coban, S., Terzi, A., Ates, M., Aksoy, N., Cakir, H., Ocak, A. R., and Bitiren, M. Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver. World J Gastroenterol. 9-7-2008;14(33):5204-5209. View summary.

Yildiz, F., Coban, S., Terzi, A., Savas, M., Bitiren, M., Celik, H., and Aksoy, N. Protective effect of Nigella sativa against ischemia-reperfusion injury of the kidneys. Reindeer fail. 2010;32(1):126-131. View summary.

Zaoui, A., Cherrah, Y., Alaoui, K., Mahassine, N., Amarouch, H., and Hassar, M. Effects of Nigella sativa fixed oil on blood homeostasis in rat. J Ethnopharmacol. 2002;79(1):23-26. View summary.

Zaoui, A., Cherrah, Y., Lacaille-Dubois, M.A., Settaf, A., Amarouch, H., and Hassar, M. [Diuretic and antihypertensive effects of Nigella sativa in spontaneously hypertensive rats]. Therapy 2000;55(3):379-382. View summary.

Zaoui, A., Cherrah, Y., Mahassini, N., Alaoui, K., Amarouch, H., and Hassar, M. Acute and chronic toxicity of Nigella sativa fixed oil. Phytomedicine 2002;9(1):69-74. View summary.

Akhtar MS, Riffat S. Field trial of Saussurea lappa roots against nematodes and Nigella sativa seeds against cestodes in children. J Pak Med Assoc 1991;41:185-7. View summary.

Aqel M, Shaheen R. Effects of black cumin seed essential oil on rat and guinea pig uterine smooth muscle. J Ethnopharmacol 1996;52:23-6. View summary.

Badary OA, Al-Shabanah OA, Nagi MN, et al. Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone. Eur J Cancer Prev 1999;8:435-40. View summary.

Chakravarty N. Inhibition of histamine release from mast cells by nigellone. Ann Allergy 1993;70:237-42. View summary.

Daba MH, Abdel-Rahman MS. Hepatoprotective activity of thymoquinone in isolated rat hepatocytes. Toxicol Lett 1998;95:23-9. View summary.

Dehkordi FR, Kamkhah AF. Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Fundam Clin Pharmacol 2008;22:447-52. View summary.

Hanafy MS, Hatem ME. Studies on the antimicrobial activity of black cumin (black cumin). J Ethnopharmacol 1991;34:275-8. View summary.

Haq A, Abdullatif M, Lobo PI, et al. Black cumin: effect on human lymphocytes and polymorphonuclear leukocyte phagocyte activity. Immunopharmacology 1995;30:147-55. View summary.

Haqqaq EG, Abou-Moustafa MA, Boucher W, Theoharides TC. The effect of a herbal water extract on histamine release from mast cells and on allergic asthma. J Herb Pharmacother 2003;3:41-54. View summary.

Houghton PJ, Zarka R, de las Heras B, Hoult JR. Solid black cumin oil and thymoquinone derived from it inhibit eicosanoid formation in leukocytes and lipid peroxidation of the membrane. Planta Med 1995;61:33-6. View summary.

Keshri G, Singh MM, Lakshmi V, Kamboj VP. Postcoital contraceptive efficacy of black cumin seed in rats. Indian J. Physiol. Pharmacol. 1995; 39:59-62. View summary.

Medenica RD. Using black seed to boost immune function. U.S. Patent 5,482,711 Issued January 9, 1996. Obtained from US Patent and Trademark Ofc on April 12, 2000. www.uspto.gov/patft/index.htm.

Nagi MN, Alam K., Badary OA, et al. Thymochinon schützt bei Mäusen über einen antioxidativen Mechanismus vor Tetrachlorkohlenstoff-Hepatotoxizität. biochem. Mol. Biol. Int. 1999;47:153-9. View summary.

Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, et al. Clinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trial. Medicinski Arhiv 2012;66(3):198-200. View summary.

Salomi NJ, Nair SC, Jayawardhanan KK, et al. Antitumour principles from Black seed seeds. Cancer Lett 1992;63:41-6. View summary.

Tennekoon KH, Jeevathayaparan S, Kurukulasooriya AP, Karunanayake EH. Possible hepatotoxicity of Nigella sativa seeds and Dregea volubilis leaves. J Ethnopharmacol 1991;31:283-9. View summary.

Worthen DR, Ghosheh OA, Crooks PA. The in vitro anti-tumor activity of some crude and purified components of blackseed, Black seed L. Anticancer Res 1998;18(3A):1527-32. View summary.

How much oil of oregano should I take per day?

Pay attention to the dosage recommended by the oil’s manufacturer. Research has shown that people can take as much as 600 mg of oregano oil per day without negative effects.

Oregano Oil: Is It Good for You?

Oregano is also highly valued for its medicinal value. Its leaves are crushed and mixed with oil to make oregano oil. The essence extracted from the herb can be taken orally, applied directly to the skin, or even inhaled depending on the condition you are targeting.

Oregano oil is made from the oregano herb, a wild plant that belongs to the mint family. It is native to many Mediterranean countries and is a particularly common part of Spanish, Greek and Italian cuisine. People use it as a side dish or condiment in many different dishes.

Health Benefits

A rich source of antioxidants, oregano oil can help repair the body’s cells and reduce the rate of aging and the risk of some diseases. Oregano contains pyridoxine, also known as vitamin B6, which is necessary for healthy blood vessels and skin.

In addition to these nutrients, oregano is also a good source of magnesium, a necessary nutrient that many people are deficient in. Adequate intake of magnesium is important for maintaining strong bones, and low magnesium levels are a leading cause of osteoporosis.

Oregano oil is also known for a number of other health benefits, such as:

cholesterol management

Oregano oil has been found to support healthy cholesterol levels. A study of 48 people who took a small amount of oregano oil after each meal showed a significant reduction in their LDL (“bad”) cholesterol, which is a leading cause of clogged arteries that can lead to heart disease.

Promotes digestive health

Oil from oregano is commonly used to treat digestive problems such as abdominal cramps, bloating, irritable bowel syndrome, among others. As more research continues, experts have found that oregano is rich in carvacrol. This is known to be effective against types of bacteria that cause indigestion.

treat fungal infections

Oregano oil is very high in thymol, an organic compound also found in thyme and other herbs. Researchers have linked thymol to treatments for several types of fungal diseases that affect the skin, including toenail fungus, yeast infections, athlete’s foot, and others.

Does Oil of Oregano detox your body?

The important benefit oil of oregano can bring to gut health is its broad antimicrobial spectrum effect. This can help cleanse the intestines and clear out any remaining bacterial infections, overgrowths, or fungal infections.

Oregano Oil: Is It Good for You?

Article Evidence-Based Evidence-Based This article is based on scientific evidence written by experts and peer-reviewed. Our team of licensed nutritionists and nutritionists strive to be objective, unbiased and honest, presenting both sides of the argument. This article contains academic references. The numbers in brackets (1, 2, 3) are clickable links to peer-reviewed academic papers. Oregano Oil Benefits: How This Herbal Antimicrobial Can Help Your Health Written by Dr. Michael Ruscio, DNM, DC on June 25, 2021

The antibacterial, antifungal, and anti-inflammatory properties of oregano

KEY FINDINGS Oregano oil contains active ingredients with antifungal, antibacterial, anti-inflammatory and antioxidant properties.

The oil can give a boost to balance the bacteria and fungi in your gut and help eliminate pathogens (bad microbes) like candida.

It is recommended to use oregano oil and other herbal antimicrobials as needed for chronic health conditions after changing your diet and starting probiotics.

You probably already have a jar of dried oregano in your kitchen cupboard, or enjoy this fresh Greek herb in a delicious oregano pesto or other Mediterranean-inspired dish.

But aside from its culinary uses, the oregano plant — particularly oregano oil, which is extracted from the leaves — has some important health benefits that can help cleanse your gut and restore balance and well-being. This, in turn, may help with gut-related inflammation and autoimmune disorders (including brain fog, fatigue, and colitis).

What is oregano oil?

The oregano herb, Origanum vulgare L, belongs to the mint family, which also includes mint and marjoram. Originally grown in Greece, oregano has known antioxidant activity and antimicrobial properties [1 Trusted SourcePubMedGo to source].

Oregano oil is extracted from oregano leaves. Its chemical composition contains a higher concentration of active ingredients than the whole herb.

The two main active ingredients (both belonging to the phenolic family of antioxidants) in Origanum vulgare L-Oil are:

carvacrol

thymol

Rosmarinic acid is a third helpful ingredient in oregano oil.

A reputable, science-based oregano oil product will have standardized levels of active ingredients. A guaranteed amount of thymol and carvacrol should be listed on the label.

Oregano Essential Oil vs. Oregano Oil

It is worth noting that an oregano essential oil sold for purposes such as aromatherapy is different from vegetable oregano oil and the essential oil should not be consumed internally.

Oregano essential oil is generally used after it has been dispersed in a carrier oil such as coconut oil or olive oil. It is then used for an aromatherapy massage or applied topically to treat skin conditions.

Health Benefits of Oregano Oil

Oregano has long been used as a traditional herbal medicine in humans. More “in vivo” (in living organisms) studies are needed, but laboratory and test tube (in vitro) studies suggest this may be helpful for:

How oregano oil helps with intestinal problems

The powerful antimicrobial effects of oregano oil can help relieve chronic gut symptoms.

For background: Many symptoms and conditions such as colitis, thyroid problems and general brain fog and fatigue can start in the gut. They may be the result of imbalances and lack of diversity in gut bacteria (gut dysbiosis), small bowel bacterial overgrowth (SIBO), or fungal or parasitic infections [10, 11, 12].

The important benefit that oregano oil may bring to gut health is its broad spectrum antimicrobial activity. This can help clean out the colon and eliminate any remaining bacterial, growth, or fungal infection.

Residual pathogens or bacterial imbalances may include:

Candida

Bacterial growths such as SIBO

H. pylori (which can cause stomach inflammation and ulcers)

Parasitic Infections

The science behind oregano oil and gut health

Scientific literature shows that oregano herb extracts are antimicrobial, antiviral and hepatoprotective. They also have analgesic (pain-relieving) effects and anti-inflammatory properties [13 Trusted SourcePubMedGo to source].

In particular, oregano oil and its active ingredients have been shown to help cleanse and rebalance the gut:

When to use antimicrobials

But before you jump straight into oregano oil, let’s look at where it should be used in a balanced approach to healing your gut.

Review the flowchart below, and you’ll see that oregano—an antimicrobial—appears as the third step (“removal”) in my eight-step protocol for treating problematic symptoms caused by a problem in your gut.

In a gut healing program, it generally makes the most sense to tackle your diet first, followed by a regimen of probiotics to help balance your gut. There is good scientific evidence and treatment guidelines from around the world to support this [18 Trusted SourcePubMedGo to source, 19 Trusted SourcePubMedGo to source].

If these two steps are not effective, herbal antimicrobials such as oregano oil can be added as the next part of your gut healing journey.

Step 1: Implement your diet

To start the movement to a healthier gut, I recommend a gut healing elimination diet designed to:

Reduce or eliminate foods that can irritate your gut lining or feed imbalanced gut bacteria.

Healing and Sealing of Intestinal Permeability (Leaky Gut)

Feed your good gut bacteria

Reduce inflammation

Help you understand which foods trigger your symptoms

The Paleo diet is the easiest diet that I recommend trying first as a framework for your elimination diet because it is a well-rounded diet that has been shown to reduce inflammation by minimizing exposure to foods that can provoke an immune response [20 Trusted SourcePubMedGo to source, 21 Trusted SourcePubMedGo to source]. These include sugar, unhealthy fats, chemical additives, and common problem foods like dairy, gluten, and soy.

If a paleo diet doesn’t relieve symptoms after a week or two, you can try gradually restrictive diets like the low-FODMAP diet or an autoimmune protocol diet.

It may take a few weeks to find a diet that you are happy with and enjoy so that you feel healthier. If you’re at this point, you can move on to step two.

Step 2: Support with probiotics

Once you find a healthy diet that works for you, you can support it with probiotic supplements that help:

The most popular probiotics contain a combination of Lactobacillus and Bifidobacterium species, but I recommend adding two more – Saccharomyces Boulardii (a healthy fungus) and a soil-based probiotic – for best results. These three categories of probiotics each have their own benefits, and meta-analysis has shown that multi-strain probiotics tend to result in greater symptom improvement than single-strain probiotics [28 Trusted SourcePubMedGo to source, 29 Trusted SourcePubMedGo to source].

introduction of antibiotics

Let’s imagine that after completing the above two steps, some stubborn symptoms remain.

Now is a good time to add a microbial agent like oregano oil to your treatment regimen.

Oregano oil can significantly increase symptom relief for many people. Introducing this antimicrobial can help relieve your persistent GI issues, brain fog, and fatigue.

Cautious approach

When you first start dealing with microbes, your body can react in a number of ways. Be prepared for a possible short-term worsening of symptoms from “die-off.”

Dying off can temporarily result in:

Increased fatigue

headache

indigestion

Flu-like symptoms

On the plus side, die-off symptoms are a good sign that an antimicrobial like oregano is working.

However, long-term spurts from introducing oregano oil or any other antimicrobial may mean it isn’t suitable for you, or you may need a lower dose.

Other herbal antimicrobials that might work for you instead include artemisinin and berberine. It’s definitely worth researching a few different antimicrobials to find something that works for you.

Watch after

Oregano and oregano oil are certified by the U.S. Food and Drug Administration (FDA) Food Ingredients Generally Recognized As Safe (GRAS) [30 Trusted SourcePubMedGo to source]. However, you should always follow your doctor’s medical advice.

If you are breastfeeding, taking oregano oil in excess of what you would reasonably consume from food is not recommended.

Antimicrobial Resistance

Antimicrobial resistance occurs when bacteria, viruses, fungi or parasites change over time in a way that makes them less susceptible to destruction by a pharmaceutical or natural antibiotic.

Antimicrobial resistance is a public health concern as it makes infections more difficult to treat and increases the risk of spreading disease and serious illness [31]. Being responsible for our own health and that of others means that we should not overuse antimicrobials of any kind.

However, herbal compounds like oregano oil are less likely to contribute to antibiotic resistance than pharmaceutical drugs. This is because herbal compounds have broad-acting pharmacology that allows control of drug-resistant organisms [32 Trusted SourcePubMedGo to source].

In other words, while bacteria and pathogens can develop resistance to drugs that essentially work in one way, they are generally less likely to develop resistance to herbal compounds that work in multiple different ways.

pull everything together

Breaking free from distressing gut symptoms can be problematic, and it can be discouraging when revising your diet and taking probiotics aren’t having the desired effects.

This is where taking antibiotics can really come in handy, and oregano oil is one of the most helpful options.

It can have powerful colon cleansing effects that can provide greater relief for some people than just diet and probiotics alone.

If you have additional questions after reading this article, consider scheduling a virtual or in-person consultation at our Functional Medicine Center, or read more about my eight-step protocol for restoring your digestive system health in Healthy Gut, Healthy You.

Is black seed oil good for lungs?

Black seed oil as an adjunct therapy in COPD patients significantly improves lung functions and maintains the oxidant-antioxidant balance, in addition to its effect in reducing the aggravation of inflammatory processes in COPD patients by limiting the level of inflammatory markers (TNF-α and IL-6).

Oregano Oil: Is It Good for You?

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What is black seed oil good for immune system?

It’s a powerful immune modulator, keeping the immune system in balance so it doesn’t overreact or underreact. Black seed oil also quenches dangerous inflammation and boosts appropriate immune function, resulting in enhanced protection against infections, while it also eases coughs, bronchitis symptoms, and colds.

Oregano Oil: Is It Good for You?

Immune System Health

Black seed oil (AKA, black cumin and black cumin seed) provides powerful immune system support. It is a powerful immunomodulator that keeps the immune system balanced so it doesn’t over- or under-react. Black seed oil also quenches dangerous inflammation and boosts appropriate immune function, resulting in improved protection against infection, while also relieving coughs, bronchitis symptoms, and colds.1 2 3 New research shows that it’s due to its immune-regulating, anti-inflammatory, and antioxidant benefits Black Seed Oil is a powerful ally of the immune system, especially when it comes to respiratory health.4 5

Allergies & Asthma

About 18 million Americans suffer from allergies and almost 19 million from asthma. These conditions can range from pure annoyance to debilitating and life-threatening conditions. Studies show that thymoquinone causes a significant reduction in inflammatory molecules that play a role in both asthma and allergy-related symptoms.6 7 A study in patients with allergic rhinitis yielded promising results showing that treatment with black seed oil led to a drastic reduction Reductions resulted in IgE antibodies (antibodies that indicate an allergic reaction) in nasal secretions as well as a significant reduction in nasal congestion and itching, runny nose and sneezing attacks.8 Studies also show that black seed oil is a force to be reckoned with when it comes to treating asthma. Black seed oil and thymoquinone themselves “trigger a relaxation of the windpipe and large airways (bronchi), both of which can spasm during an asthma attack.” Inflammatory cells in their lung tissue “equivalent to those induced by dexamethasone, a potent immunosuppressive steroid.”11

Tonsillitis & Sinusitis

Another study showed that taking black seed oil for acute tonsillitis and sore throats, infections that are often viral in nature, significantly relieved sore throats and reduced the need for pain medication.12 Black seed oil also shines in the treatment of sinusitis. The results of a study showed its therapeutic potential in the treatment of sinusitis through its “…anti-inflammatory, antioxidant, antihistaminic, immunomodulatory, antimicrobial and analgesic effects. The oil can inhibit sinus and respiratory tract inflammation and microbial infections, and ultimately help the patients suffering from clinical symptoms of sinusitis such as nasal congestion, headache, neck pain, earache and toothache,” the study found.13

Cardiovascular health, blood sugar and weight maintenance

Black seed oil neutralizes the oxidation of lipids (fats) and reduces the effects of oxidized LDL cholesterol, a key trigger in atherosclerotic plaques that block blood flow and cause heart attacks and strokes.14 Studies have shown that black seed oil can improve lipid profile and cardiovascular health -Prevent disease in both healthy people and hyperlipidemic patients. Hyperlipidemia is a condition in which high levels of fat particles such as cholesterol and triglycerides are present in the blood.15 Black seed oil is believed to benefit cardiovascular health in part by inhibiting the absorption of cholesterol in the gut and reducing cholesterol production in the liver. 16

Black seed oil also lowers high blood pressure. The results of a double-blind, eight-week study looking at the effects of black seed oil on hypertension showed that the oil-treated group at 2.5 ml twice daily had significantly lower systolic and diastolic readings compared to the baseline and placebo groups at the end of the study, without side effects.17

Black seed oil, when combined with antidiabetic drugs and statins, may also help diabetics control both dyslipidemia (abnormal levels of cholesterol or lipids in the blood) and blood sugar.18 A review of 13 clinical trials of the hypoglycemic effects of black seed oil, including eight patients with insulin resistance, found found that black seed use reduced fasting blood sugar, insulin levels, and insulin resistance.19 20

Also, a common risk factor for cardiovascular disease is body weight and general metabolic profile. A double-blind, randomized, controlled study of 90 obese women who took either black seed oil or a placebo for eight weeks resulted in significantly lower weight and waist circumference in the women taking black seed oil compared to the placebo group. There was also a significant decrease in triglyceride and LDL cholesterol levels in the black seed oil group compared to the placebo group.21

With its wide ranging health benefits, black seed oil is worth adding to your supplement repertoire so it can come to the rescue when you need it!

References available upon request

How long does it take for black seed oil to work?

Based on this comparative study between acne treatment with black seed and benzoyl peroxide, it can be said that black seed oil takes anywhere from 6- 8 weeks for noticeable improvements.

Oregano Oil: Is It Good for You?

Black seed oil has been considered a miracle oil in the Middle East for centuries. It is currently gaining ground in the mainstream beauty industry as an ingredient for acne-free skin.

While other active ingredients like benzoyl peroxide and retinol are known to be popular acne remedies, they sometimes have side effects like dryness, stinging, itching, and burning.

Black seed oil is presented as a natural option that is less invasive while still providing the same result. But is this oil really good for acne-prone skin? In this guide you will find everything you need to know about this wonder ingredient.

What is Black Seed Oil?

Black seed oil is obtained from the cold pressing of the seeds of the Nigella sativa (fennel flower) plant. This plant grows in parts of the Middle East, Asia, Eastern Europe and North Africa.

It has been used in Asian, Aruyvedic and Arabic cultures for over 2000 years for its medicinal properties.

The pure and natural black seed oil has a golden brown color. It has a shelf life of 2 years and is non-comedogenic. Its scent can be described as mild, earthy, spicy or woody. It is also known as black cumin oil, black cumin oil, black onion seed or kalonji oil.

This lightweight oil has antioxidant, anti-inflammatory, antibacterial, and antifungal properties that make it suitable for combination and acne-prone skin. These are also the reasons why many brands today are turning to this natural oil to formulate acne treatment products. Below are some of the incredible benefits of black seed oil.

Benefits of Black Seed Oil for Acne Prone Skin

Destroys acne-causing bacteria

Black seed oil contains the active ingredient thymoquinone, a powerful antibacterial agent that helps prevent acne vulgaris. This bacterium is responsible for the appearance of whiteheads and blackheads.

It has an essential fatty acid profile consisting of linoleic acid (50.2%), oleic acid (19.9%) and stearic acid (2.5%). Its content of linoleic acid helps to unclog pores and regulate sebum production in oily skin, while oleic acid moisturizes.

A 2010 clinical study of 62 patients with mild to moderate acne found that a lotion containing 20% ​​black seed oil was more effective at reducing the appearance of acne lesions than a lotion containing 5% benzoyl peroxide.

Has a strong antioxidant and anti-inflammatory effect

Black seed oil is packed with phenolic compounds (thymoquinone, thymol, carvacrol) and saponins (alpha-hederin) that give it antioxidant properties.

When exposed to free radicals, skin cells become damaged, leading to inflammation in acne-prone skin. The antioxidants found in black seed oil help prevent this by reducing oxidative stress and neutralizing free radicals present on the skin.

This oil also works to smooth out signs of aging. Its high concentration of linoleic acid helps boost ceramide production for a healthy lipid barrier.

Facilitates absorption of other skin care products

Black seed oil has a high concentration of linoleic acid. As a result, it can improve the absorption of other products into the skin. It does a lot to make the other products in your skincare routine more effective as they are able to reach deeper layers of the dermis.

Antifungal properties

A recent 2019 study found that black seed essential oil treats pathogenic yeast and dermatophyte fungi (a group of fungi that cause skin conditions). These include skin conditions such as fungal acne, facial, hair and body ringworm; Athlete’s foot, jock itch and onychomycosis.

Heals acne scars

This oil has been known over the years to speed up wound healing like acne scars. Although it does not boost collagen production, it is effective in reducing scars. By reducing the inflammation caused by acne, it speeds up the skin’s healing process. In addition, it helps inhibit the growth of bacteria that could lead to further pore infection.

Other Benefits of Black Seed Oil

Soothes eczema and psoriasis

When applied topically, black seed oil helps reduce inflammation and relieve itching caused by eczema thanks to its anti-inflammatory properties. Tested on hand eczema, it proved more effective than Eucerin.

The black seed oil also helps in the treatment of psoriasis. It has been shown to boost the immune system and inhibit the proliferation of infected skin cells. Its antioxidant, anti-inflammatory, antibacterial, and anti-hostile effects all work together to prevent and treat psoriatic lesions on the skin.

Patients in this study treated with both the oil and oral doses experienced complete healing.

Treats hypopigmentation and vitiligo

Hypopigmentation occurs when your skin cells don’t produce enough melanin. Vitiligo is a skin condition caused by the loss of the skin’s pigment-producing cells, also called melanocytes. In both cases, the result is the appearance of lighter patches of skin all over the body.

According to a review published in the Journal of Dermatology & Dermatologic Surgery, thymoquinone, the most active ingredient in black seed oil, induces melanin production when exposed to melanocytes.

When tested on patients in this clinical study, topical application of black seed oil resulted in a decrease in vitiligo area after six months of daily use.

Drinking black seed oil for acne: does it help?

When it comes to treating acne, all available data only highlights topical use of black seed oil. However, it has been proven that taking black seed or black seed oil capsules has pharmaceutical benefits. Especially in diseases such as diabetes, high blood pressure, asthma, arthritis, skin cancer, cardiovascular diseases, diabetes, Alzheimer’s, epilepsy, amyotrophic lateral sclerosis, etc.

How to use black seed oil for acne

There are many products on the market that are formulated with this rich oil. From serums to facial oils to acne fights and spot treatments the list is endless etc.

It is safe to apply black seed oil directly to the face. It’s a light and non-greasy oil with a comedogenic rating of 2. That means it won’t clog your pores.

You can also use it as a facial oil in combination with other natural oils that are great for acne-prone skin, such as rosehip oil, watermelon seed oil, or evening primrose oil.

Add it to your homemade face masks for a special acne treatment. Just be careful how much you use to avoid wasting the products.

Always do a patch test on your forearm 24 hours in advance to check for allergies. If you are taking any medication, be sure to check with your doctor about possible contraindications before use.

How to buy quality black seed oil for acne

To date, there is no standard way to verify the quality of all black seed oils on the beauty market. Therefore, the quality of the products available in the market will vary from one vendor to the next.

Then how is it possible to know that you are buying quality black seed oil? Well, here are some pointers:

Make sure the oil you buy has been certified organic by the regulators in the country where you buy it. Quality black seed oil should come from trusted, certified organic, vegan, and non-GMO sources. These are always the best on the international market. Get samples obtained by cold press extraction. This extraction method guarantees less damage to the nutrients contained in the oil. Oil obtained through heat extraction or chemical extraction can be mixed with cheap carrier oils that could be harmful to your body. Choose oil that is stored in an amber bottle rather than a clear one. It protects the oil from sunlight and heat damage. Finally, look for suppliers that sell nitrogen-flushed black seed oil for better preservation.

frequently asked Questions

How long does black seed oil take to get rid of acne?

Based on this comparative study between black seed and benzoyl peroxide acne treatment, it can be said that black seed oil takes between 6 to 8 weeks to produce noticeable improvements.

Is black seed oil good for fungal acne?

Yes. Black seed oil is effective against fungal acne. Fungal acne occurs as a result of infection of hair follicles in the skin by yeast. Black seed oil contains phenolic compounds like thymoquinone and thymol that help clear yeast infections.

Does black seed oil work for cystic acne?

There is no data to suggest its effectiveness against cystic acne.

Black Seed vs Black Seed Oil vs Black Seed Oil Capsules: Which is Best for Acne?

Black seeds are the seeds of the Nigella sativa plant. They can be taken for their nutritional benefits.

Black seed oil is the oil obtained from the cold pressing of black seed. Black seed oil has been shown to have dermatological benefits in treating skin conditions like acne, eczema, and psoriasis. Again, there is no scientific evidence that taking any of these will help treat acne. But it is recommended for dietary purposes

Black seed oil capsules are capsules that contain black seed oil. This is a form of packaging for easy consumption. Black seed oil and oil capsules are more concentrated than seeds. Therefore, it is better to include it in your diet.

Can black cumin oil be taken during pregnancy?

There is not yet enough scientific data to claim that the use of black seed oil is recommended for pregnant women. It is best to consult your doctor before use.

Does Oil of Oregano cause blood clots?

Oil of oregano may reduce the amount platelets clump together (platelet aggregation) and may reduce the way other blood clotting factors work. Oil of oregano may interact with other natural health products that also affect blood clotting, increasing the risk of bruising and/or bleeding.

Oregano Oil: Is It Good for You?

Oil of oregano pressure side

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Common names: origanum oil, wild marjoram, oregano oil

Scientific names: Origanum vulgare

Conclusion Efficacy: No studies were conducted in patients with rheumatic diseases. Its use is not recommended. Safety: Considered possibly safe when used as a medicinal product.

What is oregano oil?

Oil of Oregano is oil from the oregano plant.

It is commonly used as a spice in cooking due to the flavor of its leaves.

The leaves, stems and flowers are used to make medicine.

What is it used for in people with rheumatic diseases?

It has been applied to the skin to relieve muscle and joint pain in people with rheumatoid arthritis.

It is more commonly used for cough and cold symptoms, some infections, heartburn and gas, and skin conditions.

How is it supposed to work?

It is not known how oil of oregano could help with rheumatic diseases.

Oregano oil contains chemicals (carvacrol, thymol, eugenol) that help slow bacterial growth and kill fungus.

It works? What science says:

There are no studies on the use of oregano oil in rheumatic diseases.

What are possible side effects and what can I do about them?

Oregano oil is considered Likely Safe when applied to the skin or eaten in prepared meals.

It is not known if oregano oil is safe when used as an oral medicine. Large amounts of oregano can cause stomach upset.

Oregano oil can also cause allergic reactions. Do not use oregano oil if you are allergic to plants from the mint family such as basil, lavender, sage and more.

interactions

With drugs:

Oregano oil can decrease the amount of platelets (platelet aggregation) and reduce the effect of other blood clotting factors. Oregano oil may increase the risk of bleeding in patients taking anticoagulants/antiplatelets. Common antiplatelet and anticoagulant drugs may include: warfarin (Coumadin), ASA (Aspirin) and clopidogrel (Plavix), ticagrelor (Brilinta), prasugrel (Efient), enoxaparin (Lovenox), dalteparin (Fragmin), dabigatran (Pradaxa), rivaroxaban (Xarelto ), apixaban (Eliquis) and others.

Oil of oregano can lower blood sugar. People with diabetes should monitor levels more closely.

Oregano oil can affect how lithium is removed from the body. Patients taking lithium should be monitored more carefully or the use of oregano oil should be avoided.

For other diseases:

Oregano oil can affect blood clotting, which can increase the risk of bleeding during surgery. Stop using oil of oregano at least 2 weeks before surgical procedures.

With other natural health products:

Oregano oil can decrease the amount of platelets (platelet aggregation) and reduce the effect of other blood clotting factors. Oregano oil may interact with other natural health products that also affect blood clotting and increase the risk of bruising and/or bleeding.

Such as: garlic, ginkgo, ginger, certain types of ginseng, red clover, and others.

Oregano oil can decrease the absorption of certain minerals like iron, zinc, and copper.

For more information about oregano oil, consult your doctor and pharmacist.

What happens if you take too much oil of oregano?

In large doses, oregano oil may be toxic — and even lethal. Oregano may have diuretic effects. Large amounts of oregano can upset the stomach. Oregano oil may cause rash when applied to the skin.

Oregano Oil: Is It Good for You?

Oregano is an herb commonly used in cooking. The oil extracted from its leaves has a long history of medicinal uses. Over the centuries, it has been used to treat a variety of ailments, including snake and spider bites, respiratory problems, and menstrual cramps. Today it is marketed for treating a long list of health conditions.

Why do people take oregano oil? There are many claims about the use of oregano oil. However, there is little evidence that it is effective for all conditions. For example, oregano oil is often marketed as a treatment for intestinal parasites and the symptoms that accompany them, such as: Bloating

cramps

constipation

Diarrhea

Fatigue A single study found that taking 200 milligrams of oregano oil three times a day for six weeks eliminated three such parasites. But the study was small, inconclusive, and funded by a dietary supplement manufacturer. Some laboratory studies show that oregano or its components have properties that may kill some food-borne germs. However, there is no evidence that it helps prevent food poisoning.

Does oregano oil raise blood pressure?

According to a September 2021 study published in the American Journal of Clinical Nutrition, people who ate more herbs and spices—in particular, cinnamon, turmeric and oregano—recorded lower blood pressure readings 24 hours later.

Oregano Oil: Is It Good for You?

Hypertension is one of the top seven factors in our overall risk profile for the #1 cause of death in the United States: heart disease.

You’re probably familiar with the advice to eat less sodium and more potassium when looking for the best blood pressure-lowering diet, but salt isn’t the only flavor element that can affect your tick. It turns out that the choice of spices in your food can also help keep your blood pressure in check. According to a September 2021 study published in the American Journal of Clinical Nutrition, people who ate more herbs and spices — specifically cinnamon, turmeric, and oregano — had lower blood pressure readings 24 hours later.

Before we dive into the details, it’s worth taking this with a small grain of salt as only 71 participants, between the ages of 30 and 75, took part in the study. Still, the limited sample size may inspire future research in this fairly new area of ​​scientific interest.

Each of the 71 people had at least one risk factor for heart disease and fell into the “overweight” or “obese” category on the body mass index (BMI) scale. After a 12-hour fast, participants were measured for blood pressure, height, weight, waist circumference, fasting blood sugar, and arterial flexibility. They then wore blood pressure monitors for the following 24 hours.

The 71 participants were randomly divided into three groups:

Low Spice Diet (0.5 grams per day)

Moderately spiced diet (3.3 grams per day)

High Spicy Diet (6.6 grams per day)

They were told to then meet their daily allowance of spices with herbs and spices typical of many American diets, with a strong focus on three in particular — cinnamon, turmeric, and oregano — which the scientists learn about from previous research reports and metadata had analyzes that may relate to heart health.

Also see: Stocking Up on These 4 Super Spices

They followed their diet for 4 weeks, took a 2 week break, and then tried a different spice diet. (So ​​someone can start in the high-spice category, rest for two weeks and eat as usual, then try the low-spice diet.) At the end of each 4-week span, they completed follow-up evaluations.

The story goes on

Lamb and Beef Balti

Of the 63 people who completed all of the spice trials, the researchers found that the heavily spiced diet resulted in healthier 24-hour blood pressure readings (a proven predictor of cardiovascular death risk) than the moderate and low versions. Cholesterol, blood sugar, arterial function and other categories did not change.

“The blood pressure lowering effects of herbs and spices in a standard Western diet surprised me. We [already know] about the effects of many lifestyle factors, particularly dietary factors that can increase blood pressure—like sodium, alcohol, and caffeine—and others that can lower blood pressure, like potassium, magnesium, calcium, weight loss, physical activity, and some vitamins , including folic acid and vitamin D when intakes are low,” Penny Kris-Etherton, one of the study’s lead authors, tells Medical News Today. “But the antihypertensive effect of herbs and spices is new! When it comes to herbs and spices, up to our study, there hadn’t been a clinical study that showed benefits in lowering blood pressure.” (ICYMI, High blood pressure may speed up cognitive decline – here are 4 ways to combat both, according to doctors.)

The short time span and limited scope of this study leaves room for research to build on the required dosage, control for other dietary changes, and ensure consistent herb and spice exposure throughout the study.

See Also: 5 Insidious Reasons Your Blood Pressure Is High, According to a Nutritionist

“It will be important to assess the effects of individual spices on blood pressure and to understand the mechanism by which each lowers blood pressure,” Kris-Etherton continues to Medical News Today. “It would also be interesting to assess the effects of herbs and spices on the microbiome and to assess whether the effects of herbs and spices on [blood pressure] are modulated by changes in the gut microbiome. Beyond clinical trial research, studies are needed to evaluate effective educational programs that promote the use of herbs and spices in a healthy diet pattern that is lower in sodium, saturated fats and added sugars in relation to diet quality and clinical endpoints such as risk factors for chronic disease to teach.”

Until we know more, there’s certainly no harm in adding more herbs and spices, particularly cinnamon, turmeric, and oregano (which may also offer anti-inflammatory and blood-sugar-boosting effects) to your daily diet.

“It’s important to note that while the goal of this study was to examine the average American diet, we need major changes in average eating patterns to make our eating habits healthier and more sustainable.” While certain foods or ingredients may have small benefits on their own, we need to encourage a shift towards healthier eating across the board,” adds Simon Steenson, Ph.D., nutritionist at the British Nutrition Foundation.

Next: 7 Spices You May Not Be Using, But Should.

Does black seed oil raise blood pressure?

The oil may also help lower blood pressure. One study in 70 healthy adults noted that 1/2 teaspoon (2.5 mL) of black seed oil twice a day for 8 weeks significantly reduced blood pressure levels, compared with a placebo ( 30 ).

Oregano Oil: Is It Good for You?

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This article provides an overview of the potential health benefits of black seed oil, possible side effects, and dosage information.

Studies suggest it could have numerous health uses, including treating asthma and aiding in weight loss. It’s also applied topically to benefit skin and hair (1, 2, 4, 5).

Derived from N. sativa seeds, black seed oil has been used in traditional medicine for over 2,000 years for its many therapeutic benefits.

This shrub also produces fruit with tiny black seeds. N. sativa seeds, commonly referred to simply as black seed, have many other names, including black seed, black seed, nigella, fennel flower, and Roman coriander (2, 3).

Nigella sativa (N. sativa) is a small flowering plant that grows in southwest Asia, the Middle East, southern Europe, and northern Africa (1).

In traditional medicine, black seed oil is used to treat a variety of health conditions. As a result, it has sometimes been referred to as the “panacea”—or universal healer (4, 6).

While not all proposed medicinal uses have proven effective, black seed oil and its botanicals have been linked to several health benefits.

Rich in antioxidants

Black seed oil is rich in antioxidants — plant compounds that help protect cells from damage caused by unstable molecules called free radicals (7, 8, 9, 10).

Antioxidants are important for health, as research has shown that they can reduce inflammation and protect against conditions like heart disease, Alzheimer’s, and cancer (11).

Black seed oil in particular is rich in thymoquinone, which has powerful antioxidant and anti-inflammatory effects. As a result, studies suggest this compound may protect brain health and help treat various types of cancer (7, 12, 13, 14).

May help treat asthma

Asthma is a chronic condition in which the lining of your airways swells and the muscles around it tighten, making it difficult for you to breathe (15).

Research has shown that black seed oil, and specifically the thymoquinone in the oil, may help treat asthma by reducing inflammation and relaxing muscles in the airways (4, 16, 17).

A study of 80 adults with asthma found that taking 500 mg of black seed oil capsules twice a day for 4 weeks significantly improved asthma control (16).

Although promising, larger and longer studies are needed to evaluate the long-term safety and effectiveness of black seed oil supplements in treating asthma.

May support weight loss efforts

Although the exact mechanism is not fully understood, research shows that black seed oil may help reduce body mass index (BMI) in individuals with obesity, metabolic syndrome, or type 2 diabetes (18, 19, 20) .

In an 8-week study, 90 women aged 25–50 with obesity were given a low-calorie diet and either a placebo or 1 gram of black seed oil per meal for a total of 3 grams per day (21).

At the end of the study, those taking the black seed oil had lost significantly more weight and waist size than the placebo group. The oil group also experienced significant improvements in triglyceride and LDL (bad) cholesterol levels (21).

Despite these promising results, more research is needed on the long-term safety and effectiveness of taking black seed oil for weight loss.

Can lower blood sugar levels

In people with diabetes, consistently high blood sugar levels have been shown to increase the risk of future complications, including kidney disease, eye disease, and stroke ( 22Trusted Source ).

Several studies in people with type 2 diabetes indicate that a daily dose of 2 grams of crushed black seed significantly lowers fasting blood glucose levels and hemoglobin A1c (HbA1c) levels, a measure of average blood glucose levels over 2–3 months can (23, 24, 25).

While most studies use black seed powder in capsules, black seed oil has also been shown to help lower blood sugar levels (25).

A study of 99 adults with type 2 diabetes found that both 1/3 teaspoon (1.5mL) and 3/5 teaspoon (3mL) of black seed oil per day for 20 days reduced HbA1c levels compared to a placebo significantly (26). .

May help lower blood pressure and cholesterol levels

Black seed oil has also been studied for its potential effectiveness in lowering blood pressure and cholesterol levels.

High blood pressure and high levels of total and LDL (bad) cholesterol are important risk factors for heart disease (27).

Two studies, one in 90 women with obesity and the other in 72 adults with type 2 diabetes, found that taking 2-3 grams of black seed oil capsules per day for 8-12 weeks reduced LDL (bad) and Significantly lowered total cholesterol levels (21, 28).

Another study of 90 people with high cholesterol observed that eating 2 teaspoons (10 grams) of black seed oil after breakfast for 6 weeks significantly reduced LDL (bad) cholesterol levels ( 29Trusted Source ).

The oil can also help lower blood pressure.

A study of 70 healthy adults found that 1/2 teaspoon (2.5 mL) of black seed oil twice a day for 8 weeks significantly lowered blood pressure compared to a placebo ( 30Trusted Source ).

While promising, general research on black seed oil for lowering blood pressure and cholesterol is limited. More research is needed to confirm the optimal dose.

Can protect brain health

Neuroinflammation is inflammation of brain tissue. It is believed to play an important role in the development of diseases like Alzheimer’s and Parkinson’s (13, 31).

Early test-tube and animal studies suggest that thymoquinone in black seed oil may reduce neuroinflammation. Therefore, it may help protect against brain diseases such as Alzheimer’s or Parkinson’s (13, 32, 33, 34).

However, there is currently very little research into the effectiveness of black seed oil in humans, particularly in relation to the brain.

A study of 40 healthy older adults found significant improvements in measures of memory, attention, and cognition after taking 500 mg of N. sativa capsules twice daily for 9 weeks (35).

Still, more research is needed to confirm the protective effects of black seed oil on brain health.

Can be good for skin and hair

In addition to medicinal uses, black seed oil is commonly used topically to help with a variety of skin conditions and to moisturize hair.

Research suggests that black seed oil may help treat some skin conditions due to its antimicrobial and anti-inflammatory effects, including (36, 37, 38):

acne

eczema

general dry skin

psoriasis

Despite claims that the oil can also help moisturize hair and reduce dandruff, no clinical studies support these claims.

Other Potential Benefits

Black seed oil may have other health benefits including:

anti-cancer effects. Test-tube studies have shown that thymoquinone in black seed oil helps control the growth and spread of various types of cancer cells (39, 40).

Test-tube studies have shown that thymoquinone in black seed oil helps control the growth and spread of various types of cancer cells ( , ). Reduce the symptoms of rheumatoid arthritis. Because of its anti-inflammatory effects, limited research suggests that black seed oil may help reduce joint inflammation in people with rheumatoid arthritis (41, 42, 43).

Because of its anti-inflammatory effects, limited research suggests that black seed oil may help reduce joint inflammation in people with rheumatoid arthritis ( , , ). male infertility. Limited research suggests that black seed oil may improve semen quality in men diagnosed with infertility (44, 45).

Limited research suggests that black seed oil may improve semen quality in men diagnosed with infertility ( , ). Antifungal. Black seed oil has also been shown to have antifungal activities. Specifically, it may protect against Candida albicans, a yeast that can lead to candidiasis (46, 47).

While early research on the use of black seed oil is promising, more human studies are needed to confirm these effects and the optimal dosage.

Can you take black seed oil and vitamin D together?

Study demonstrates synergy between the standardized black seed oil ThymoQuin and vitamin D3. When combined with vitamin D3, ThymoQuin reduced inflammatory biomarkers and upregulated immune response.

Oregano Oil: Is It Good for You?

A recent study1 published in the Journal of Food & Nutritional Sciences examined the immunomodulating effects of black seed oil and vitamin D3 on mesenchymal stem cells (MSCs) and in mice. MSCs can modulate inflammatory responses and sense various inflammatory signals. Two different black seed oils were used in the study: ThymoQuin (TQ), standardized to 3% thymoquinone and low in free fatty acids, from TriNutra of Israel, and a commercial black seed oil (CBSO) that was high in free fatty acids.

In the in vitro portion of the study, MSCs were treated with TQ alone, CBSO alone, vitamin D3 alone, TQ with vitamin D3, and CBSO with vitamin D3 to examine the effects of each on MSC proliferation levels of inflammatory biomarkers and lipid changes in droplet count and size, adipocyte differentiation, mitochondrial biogenesis and stem cell function. Researchers found that CBSO significantly increased mean lipid droplet size compared to control, while TQ reduced mean lipid droplet size, even more than vitamin D3 alone. The combination of TQ and vitamin D3 showed a significant reduction in average lipid droplet size.

While CBSO increased TNF-alpha levels, TQ reduced expression of the inflammatory cytokine. Overall, TQ reduced the size of large lipid droplets and effectively increased the area of ​​small lipid droplets, and these effects were enhanced by the addition of vitamin D3. Researchers also observed increased mitochondrial biogenesis and increased energy metabolism in the presence of TQ, which was only enhanced by vitamin D3.

In the animal protocol, 20 mice were divided into five groups: 1) lean controls, 2) high-fat diet (HFD), 3) HFD and treated with TQ for eight weeks, 4) HFD and treated with vitamin D3 for eight weeks, and 5) HFD and treated with TQ and vitamin D3 for eight weeks. After examining angiogenesis in mouse liver tissue, the researchers found that mice that ate an HFD with TQ and vitamin D3 had higher levels of the antibodies ANG-1 and SDF-1, while the HFD diet alone had the lowest levels of these antibodies , which showed an effect on the immune system.

“I have long debated the unique synergistic properties of black seed oil standardized to 3% thymoquinone and very low in free fatty acids,” said Morris Zelkha, co-founder and CEO of TriNutra, in a press release. “While previous focus was primarily on synergy with omega-3 fatty acids, we are pleased to share the results of ThymoQuin combined with vitamin D3 for enhanced immune support. Vitamin D3 is widely recognized as a necessary part of good health and to see that we can amplify its effects with ThymoQuin opens up many opportunities for new products and further research.”

Relation

Is black seed oil good for your liver?

Nigella (Nigella sativa, Ranunculaceae) seed oil (NSO) is used in Iranian traditional medicine to treat liver diseases. Experimental evidence suggests that NSO may reduce steatosis and improve lipid profiles and markers of liver function.

Oregano Oil: Is It Good for You?

Nonalcoholic fatty liver disease (NAFLD) begins with steatosis (a buildup of triglycerides in the liver) and can progress to steatohepatitis (NAFLD with inflammation and cell damage), fibrosis, cirrhosis, or hepatocellular carcinoma. No drug therapy has been approved for the treatment of NAFLD, and diet modification and exercise to reduce body weight are the only recommended treatments. Nigella (Nigella sativa, Ranunculaceae) Seed Oil (NSO) is used in traditional Iranian medicine to treat liver diseases. Experimental evidence suggests that NSO can reduce steatosis and improve lipid profiles and markers of liver function. However, clinical studies on NAFLD are lacking. Therefore, the purpose of this randomized, double-blind, placebo-controlled study was to evaluate the effectiveness of NSO in the treatment of NAFLD.

Patients (N=120; mean age 47 years) with ultrasound-confirmed NAFLD participated in this study, which was conducted at Baqiyatallah Hospital in Tehran, Iran. Excluded patients had a Child-Pugh score* greater than 7; liver disease other than NAFLD; were taking a drug that affects NAFLD; or have been pregnant, planning to become pregnant or are breastfeeding.

Cold-pressed NSO was purchased from Barij Essence Pharmaceutical Company (Kashan, Iran). The thymoquinone and fatty acid content of the NSO was determined using high performance liquid chromatography (HPLC) and gas chromatography (GC), respectively. The NSO contained 0.987 ± 0.07 mg thymoquinone per ml. The main fatty acids were linoleic acid (49.37%), palmitic acid (20.27%), oleic acid (5.76%), stearic acid (5.48%), palmitoleic acid (0.94%), arachidic acid (0.90%) and myristic acid (0.63%).

Patients were randomized to receive either 2.5 mL NSO (n=60) or 2.5 mL mineral oil (placebo; n=60). Both NSO and placebo were mixed with 1.25 mL of honey and 1.25 mL of water, and both were similar in appearance and smell. All patients were instructed to take 5 ml of the syrup every 12 hours for three months. Patients were asked not to make any changes to their diet or physical activity over the course of the study. Ultrasonography was performed at baseline and three months later, and blood samples were taken for analysis. The primary endpoints were fatty liver (assessed by ultrasound) and serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). The secondary endpoints were body mass index (BMI), complete blood count, and serum levels of high-density lipoprotein cholesterol (HDL-C), blood urea nitrogen, and creatinine.

There were no significant differences between the groups at baseline. Compliance was good in both groups (patients took at least 80% of their assigned doses). No patient had grade 0 fatty liver (normal liver) at baseline. However, after three months, 18 patients in the NSO group and four patients in the placebo group had grade 0 fatty liver. Overall, the NSO group had a significant decrease in fatty liver grade compared to the placebo group (P<0.01 ). ALT, AST and TG levels decreased significantly and HDL-C levels increased significantly in the NSO group compared to the placebo group (p=0.001 for all). There were no significant changes in the other measured parameters. No adverse events were reported. In conclusion, three months of NSO supplementation improved hepatic steatosis, as well as hepatic aminotransferase, TG, and HDL-C levels in patients with NAFLD. The authors hypothesize that reductions in hepatic steatosis and aminotransferases indicate that NSO may reverse liver damage and protect the liver in patients with NAFLD. Since there were no changes in body weight, the benefits of NSO were not due to weight loss. Acknowledged limitations of this study include the small sample size, short duration, and lack of elastography, a type of medical imaging to measure liver fibrosis. The authors concluded that larger, longer studies evaluating NSO in the treatment of nonalcoholic steatohepatitis, hepatic fibrosis, and cirrhosis are warranted. * The Child-Pugh score is a tool used to assess the prognosis of chronic liver disease and cirrhosis.

Is it good to take black seed oil on an empty stomach?

Black seed oil is safe for consumption as long as you are taking the recommended dosage. You can take it after food, with food or even saute your food in it but it is recommended that you take it raw to reap its benefits to the fullest since exposure to excessive heal can denature some of the compounds present in it.

Oregano Oil: Is It Good for You?

Black seed oil, a medicinal oil extracted from the seeds of the Nigella sativa shrub, is gaining popularity in the UK and we’re thankful for it!

Organic black cumin oil contains a cocktail of beneficial compounds and essential nutrients such as unsaturated fatty acids, vitamins and natural phytochemicals such as thymoquinone. These active ingredients give black cumin oil its striking properties; it heals, restores and nourishes.

From promoting skin health to strengthening your hair, from fighting cold and flu symptoms to improving digestive health and aiding in weight loss, black seed oil has a long list of health benefits.

And that’s exactly why you see it everywhere; from online shops to cosmetics stores. Black seed oil supplements come in a variety of forms; Black seed oil capsules, organic black seed oil and even black seed honey.

But as refreshing and exciting as black seed oil is, we were late in learning about its magical properties in the UK. Many have questions about this wonderful herbal remedy, its benefits, and how to use it.

Black seed oil is an amazing gift from nature and everyone should be aware of its benefits. So, to clear the fog, we’ve answered the 5 most frequently asked questions about black seed oil:

1) What is Golden Black Seed good for?

Golden black cumin is a balanced herbal blend of black cumin and turmeric. It combines the healing properties of two wonderful natural ingredients to support metabolism, boost immunity and improve memory.

Early research and pre-clinical studies show that golden black seed blends help the body maintain healthy cholesterol levels, regulate blood sugar levels, boost immunity, and improve mood. In-depth research is needed to confirm the dual effects of turmeric and black seed.

2) What does black seed oil heal?

Black seed oil is a dietary supplement with great healing potential, but it cannot replace regular medication.

Effectively nourishes black seed oil treats

Today black seed oil is used as an adjunct to treat:

Digestive tract related problems such as colic, diarrhea, constipation and hemorrhoids

Respiratory diseases such as asthma, allergies, cough, bronchitis and flu

Possible health benefits of black seed oil

Black seed oil shows promise as a treatment or effective supplement for the many conditions, but its full potential has not been properly explored. Early studies, mostly conducted on animals, indicate that black seeds, their extracts, and oil have the following potential health benefits:

Improved liver function

Black seed oil helps with diabetes

Relieves skin conditions associated with inflammation such as eczema and itching

Reduces cholesterol levels

Maintains blood pressure

Effectively reduces weight

Helps with drug withdrawal, especially opiates

Reduces seizures and epileptic seizures in children

Minimizes joint pain and rheumatism

pain relief

cancer prevention

Counteracts congestion and inflammation

Increases hair growth

menstrual regulation

black seed oil in the past

Historically, black seeds and the oil derived from them have been used to heal a variety of ailments, ranging from skin conditions like eczema and respiratory problems like asthma and coughs to headaches, dizziness and inflammation.

3) Do you take black seed oil on an empty stomach?

Black seed oil is safe for consumption as long as you take the recommended dosage. You can take it post-meal, with food, or even sear your food in it, but it’s recommended that you take it raw to reap its benefits, as exposure to over-healing can denature some of the compounds it contains.

There’s a reason why experts recommend taking herbal products and oil on an empty stomach; Some foods and beverages can prevent or slow down the effective absorption of dietary supplements or impair their effectiveness.

To get the most out of your black seed oil treatment, take the prescribed dose on an empty stomach, then wash it down with water or juice.

4) Can Nigella Sativa Cure Cancer?

Early research has shown that black seed or Nigella sativa shrub is loaded with cancer-fighting compounds like thymoquinone, but more extensive clinical evidence is needed to confirm these findings.

Most of the studies on the effects of Nigella sativa extracts like black seed supplementation on cancer have been done in cells and animals. The experimental studies revealed that thymoquinone extracted from the black seed bush reduced the growth and size of tumors in rats. The same study found that black seed supplements prevented radiation damage in rodents.

More research-based evidence is needed to confirm whether Nigella sativa supplements can effectively fight cancer in humans by reducing the growth and proliferation of cancer cells.

5) How do you take black seed oil?

Black seed oil can be ingested or applied directly to the skin. You can use black seed oil as a spice, add it to your drinks and even take it in the form of black seed oil soft gel capsules. It is most commonly used as a dietary supplement. If you’re looking for recipes, you might want to check out our guide on how to add black seed oil to your diet.

Black seed oil can also be diluted with a carrier oil like coconut oil and then applied to the skin to relieve joint pain and skin dryness.

Looking for Organic Black Seed Oil?

Nature’s Blends can help. At Nature’s Blends we bring you only the purest and most organic products. Our oil is the best in the UK because we only cold press it once to keep it organic and preservative free.

All items in our black cumin range are made from high quality black cumin seeds sourced from the vast fields of Ethiopia. For more black seed products including black seed capsules, pure black seed oil and black seed honey in the UK visit www.naturesblends.co.uk

Black Seed Oil \u0026 Oil of Oregano NATURAL ANTIBIOTICS

Black Seed Oil \u0026 Oil of Oregano NATURAL ANTIBIOTICS
Black Seed Oil \u0026 Oil of Oregano NATURAL ANTIBIOTICS


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Solutions 4 Health Oil of Wild Oregano & Black Seed Oil

Our Oil of Wild Oregano and Black Seed Oil formulation is combined with Certified Organic Extra Virgin Olive Oil from Australian produced olives.

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Source: www.evelynfaye.com.au

Date Published: 2/30/2021

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Nobody Wants to be Sick for the Holidays | Health First Network

Black Seed’s unique active ingredients; crystalline nigellone and thymoquinone work to support the digestive and respiratory systems while Oregano Oil sourced …

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Source: healthfirstnetwork.ca

Date Published: 6/9/2022

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Solution 4 Health Oil of Wild Oregano & Black Seed Oil 50ml

Wild oregano oil (Origanum vulgare) & black seed oil (Nigella sativa) work synergistically, as they combine their indivual, unique methods for combating and …

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Source: www.superpharmacy.com.au

Date Published: 3/17/2021

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Solutions 4 Health Oil of Wild Oregano & Black Seed Oil 50ml

Wild oregano oil is known to possess a powerful and therapeutic active ingredient, carvacrol. Similarly, black seed oil possesses the powerful active ingredient thymoquinone.

Wild oregano oil is one of the most powerful and potent essential oils. Its benefits are backed by numerous evidence-based scientific studies. It has been found to be effective as an antibacterial, antifungal, and anti-inflammatory product. It has been shown to help relieve rheumatic pain, respiratory conditions associated with cold and flu symptoms and has been found to support gastrointestinal health and fight urinary tract infections.

Black seed oil is extracted from the seeds of the Nigella sativa plant using the cold-pressed extraction method.

Black seed oil (Nigella sativa) is currently one of the most intensively studied plant species in the world, with many therapeutic qualities supported by the numerous clinical studies that have been carried out. Its main active ingredient, thymoquinone, has been shown to have several beneficial effects in treating patients with various diseases such as: B. Cardiovascular and respiratory diseases. Its many therapeutic benefits include bronchodilator, antihypertensive, antidiabetic, and cholesterol-lowering properties.

Wild Oregano Oil (Origanum vulgare) and Black Seed Oil (Nigella sativa) work synergistically as they combine their individual, unique methods of fighting and treating bacterial, fungal and viral infections.

Wild oregano and black seed oil is alcohol-free. It is made in Australia under strict manufacturing and quality controls in a TGA/GMP certified facility.

Ingredients: Extra virgin olive oil from certified organic farming Black cumin oil (Nigella sativa) Oregano oil from certified organic farming (Origanum Vulgare)

What Is Black Seed Oil?

Black Seed Oil is a dietary supplement extracted from the seeds of Nigella sativa, a flowering plant that grows in Asia, Pakistan and Iran. Black seed oil has a rich history dating back over 2,000 years.

Black seed oil contains the secondary plant substance thymoquinone, which can act as an antioxidant. Antioxidants detoxify harmful chemicals in the body called free radicals.

This article discusses the potential uses, risk factors, and side effects of taking the supplement.

Dietary supplements are not regulated in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. Whenever possible, choose a dietary supplement that has been tested by a trusted third party such as USP, ConsumerLabs, or NSF. But even if supplements are third-party tested, that doesn’t mean they’re necessarily safe for everyone or generally effective. Therefore, it’s important to talk to your doctor about any supplements you’re considering taking and to learn about possible interactions with other supplements or medications.

Supplement Facts Active Ingredient(s) : Thymoquinone

: Thymoquinone Alternative name(s): black cumin oil, kalonji oil, nigella sativa oil

: Black Seed Oil, Kalonji Oil, Nigella sativa Oil Legal status : Not regulated by the FDA

: Not regulated by the FDA Recommended Dose : More research is needed on dosing for specific age groups and conditions

: More research is needed on dosing for specific ages and conditions. Safety Considerations: Be careful with certain medications, herbs, and dietary supplements

Use of black cumin oil

The use of dietary supplements should be individualized and reviewed by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. No dietary supplement is intended to treat, cure, or prevent any disease.

Although research on the health effects of black seed oil is relatively limited, there is some evidence that it may offer potential benefits. Here’s a look at some key findings from available studies.

Type 2 diabetes

According to a 2017 review published in the Journal of Pharmacopuncture, black seed oil may benefit some people with type 2 diabetes.

Researchers reviewed four randomized, double-blind, placebo-controlled clinical trials involving people who ingested black seed oil, tea, or seeds. The results showed that the participants had a drop in their fasting blood sugar. It’s important to note that in most studies, black seed oil was consumed in addition to taking oral diabetes medications, a healthy diet, and exercise.

A more recent 2020 study aimed to evaluate the effect of black seed oil on inflammation, fasting blood sugar, and lipid profile in people with type 2 diabetes. The results also showed a significant reduction in fasting blood sugar levels in those who received black seed oil capsules compared to the placebo group.

Rheumatoid arthritis

According to a small study published in Immunological Investigations in 2016, black seed oil may help treat rheumatoid arthritis (RA).

In this randomized, double-blind, placebo-controlled study, 43 women with mild to moderate RA took black seed oil capsules or a placebo daily for one month. Compared to the placebo group, those using black seed oil reported a reduction in:

Arthritis symptoms (as assessed using a clinical rating scale)

blood levels of inflammatory markers

The number of swollen joints

Allergies & nasal infections

Black seed oil shows promise for treating allergies. In a 2011 clinical study of 66 people published in the American Journal of Otolaryngology, using black seed oil for two weeks reduced participants’ nasal symptoms, including:

Stuffy nose

itchy nose

Runny nose

Sneeze

Another report published in 2018 analyzed data to determine if black seed oil could help treat sinusitis. The study authors concluded that the oil has several therapeutic effects, including:

antiphlogistic

antioxidant

antihistamine

Immunomodulator (something that affects the immune system)

Antimicrobial

analgesic

obesity

According to a study, black seed oil can reduce risk factors in overweight women.

For the study, women consumed Nigella sativa oil or a placebo while on a low-calorie diet for eight weeks. At the end of the study, the following values ​​had decreased more in the group taking the Nigella sativa oil:

Another eight-week study involved overweight sedentary women and examined the combination of aerobic exercise with black seed oil supplementation. In the study, one group took black seed oil and another a placebo; both used aerobic exercise.

Researchers found that the treatment combination of diet, exercise, and black seed oil produced benefits, including lowering cholesterol. It must also be noted that this trio also resulted in weight loss compared to the placebo groups, but the benefits are unclear. Nevertheless, the authors concluded that further studies with a larger sample size and an assessment of diet are needed.

Other Uses of Black Seed Oil

While black seed oil has been studied in human, laboratory, and animal studies for the following conditions, more research is needed. Please discuss your use of black seed oil with your registered dietitian, pharmacist or healthcare provider before using for any of the following:

allergies

headache

High blood pressure

indigestion

Strengthening of the immune system

reducing inflammation

fight infections

acne

Dry hair

psoriasis

hair growth

Dry skin

What Are the Side Effects of Black Seed Oil?

Consuming a dietary supplement like black seed oil can have potential side effects. These side effects can be common or serious.

frequent side effects

Very little is known about the long-term safety of black seed oil, or how safe it is in amounts higher than those typically found in foods. However, some studies have found risks associated with black seed oil, including:

Toxicity: A component of black seed oil known as melanthin (toxic component) can be toxic in large amounts.

: A component of black seed oil known as melanthin (toxic component) can be toxic in large amounts. Allergic Reaction: Applying black seed oil directly to the skin can cause an allergic rash known as allergic contact dermatitis in some individuals. In one case report, a person developed fluid-filled skin blisters after applying Nigella sativa oil to the skin. However, they also ingested the oil, so it’s possible the blisters were part of a systemic reaction (eg, toxic epidermal necrolysis).

: Applying black seed oil directly to the skin may cause an allergic rash known as allergic contact dermatitis in some individuals. In one case report, a person developed fluid-filled skin blisters after applying Nigella sativa oil to the skin. However, they also ingested the oil, so it’s possible the blisters were part of a systemic reaction (eg, toxic epidermal necrolysis). Bleeding Risk: Black seed oil can slow blood clotting and increase the risk of bleeding. Therefore, you should not take black seed oil if you suffer from a blood clotting disorder or are taking medications that affect blood clotting. Also, stop taking black seed oil at least two weeks before a scheduled surgery.

For these reasons, be sure to talk to your doctor if you’re considering taking black seed oil. Also, remember that black seed oil is not a substitute for conventional medical care. Therefore, avoid stopping your medication without talking to your doctor.

Precautions

Children and people who are pregnant or breastfeeding should not take black seed oil supplements as their long-term safety has not been studied.

Dosage: How Much Black Seed Oil Should I Take?

Always speak to a healthcare provider before taking any supplement to ensure the supplement and dosage are appropriate for your individual needs.

Adults most commonly use black seed oil in doses of 1 to 2.5 grams daily for four to 12 weeks. Black seed powder was most commonly taken orally in doses of 1 to 2 grams daily for eight to 12 weeks. Speak to a doctor to determine what dose is best for a specific condition.

What happens if I take too much black seed oil?

As a rule of thumb, never take more than the manufacturer’s recommended dosage. If you experience any side effects, stop taking black seed oil and contact your doctor.

interactions

It’s important to carefully read a supplement’s ingredient list and nutritional information table to know what ingredients are in it and how much of each ingredient. Please check this label with your healthcare professional to discuss possible interactions with foods, other supplements, and medications.

Drug Interactions

It’s also possible for black seed oil to interact with many common medications, including:

Medicines used to treat high blood pressure, such as Norvasc (amlodipine)

immunosuppressants

diabetes medication

Serotonergic drugs (drugs that increase levels of serotonin in the brain)

Anticoagulants (medicines that slow blood clotting)

tranquilizers

Diuretics (aka water pills)

Interactions between herbs and dietary supplements

It’s also possible for black seed oil to interact with many common herb and supplement interactions, including:

Herbs and supplements that may lower blood pressure (eg, casein peptides, L-arginine, niacin, and nettle)

Herbs and supplements that may lower blood sugar (eg, aloe, bitter melon, cassia cinnamon, chromium, prickly pear)

Herbs and supplements that may slow blood clotting (eg, garlic, ginger, ginkgo, nattokinase, and panax ginseng)

Herbs and supplements with calming properties (eg, hops, kava, L-tryptophan, melatonin, and valerian)

Herbs and supplements with serotonergic (affecting serotonin in the brain) properties (e.g. 5-HTP, L-Tryptophan, SAMe and St. John’s Wort).

Iron: Black seed oil can increase the amount of iron the body absorbs.

Frequently Asked Questions What is black seed oil used for? Some people use black seed oil supplements to treat certain health conditions, including arthritis, allergies, asthma, and diabetes, and to maintain a healthy weight. While some studies support health claims, most are small and more research is needed.

Are there people who should not take black seed oil? Children and pregnant or breastfeeding people should not take black seed oil. Certain medications, herbs, and dietary supplements can interact. Always consult your doctor before beginning any dietary supplement.

How Much Black Seed Oil Should I Take? Adults most commonly use black seed oil in doses of 1 to 2.5 grams daily for four to 12 weeks. However, you should always consult your doctor first to determine if the supplement and dosage are right for you.

How to store black seed oil

Store black seed oil according to the manufacturer’s directions. Dispose of as indicated on the packaging.

Sources of black seed oil and what to look for

Below is more information on dietary and dietary supplement sources of black seed oil.

Food Sources of Black Seed Oil

Black seed oil is used in many countries as a spice and food preservative. It can be purchased commercially as an oil or powder.

Black Seed Oil Supplements

Black seed is often sold as a powder, tea, supplement, or oil. When purchasing a dietary supplement, don’t be fooled by claims that it can cure or treat a specific disease. Under FDA labeling laws, it is illegal for manufacturers to make such claims, which are rarely supported by clinical evidence.

Recap The FDA does not regulate black seed oil supplements, so use caution when choosing a supplement. Avoid products that make claims about treating health conditions and look for certified cold-pressed products.

summary

Some people use black seed oil supplements to treat certain health conditions, including arthritis, allergies, asthma, and diabetes, and to maintain a healthy weight. While some studies support health claims, most are small and more research is needed.

As a supplement, the FDA does not regulate black seed oil. You should exercise caution and work with your doctor to determine if it is right for you and at what dosage.

Oregano Oil: Is It Good for You?

Oregano oil, or oregano oil, is extracted from the leaves of the oregano plant and has been used in folk medicine for centuries as a deterrent to disease. Even today, many people use oregano oil to fight infections and colds, despite its well-known bitter, unpleasant taste. Although more research is needed on the health benefits of oregano oil, studies have confirmed that it has the following properties: Antimicrobial

antiviral

Antifungal

antioxidants

antiphlogistic

antidiabetic

Drugs for suppressing cancer

Nutritional Information One teaspoon of dried oregano leaves contains: Calories: 2.65

Protein: 0.09 grams

Fat: 0.04 grams

Carbohydrates: 0.69 grams

Fiber: 0.42 grams

Sugar: 0.04 grams Oregano is a good source of: Beta carotene

magnesium

calcium

potassium

phosphorus

folate

Ferrous oregano is also an excellent source of vitamin K. Studies have shown that vitamin K is important for bone health and blood sugar regulation. Oregano oil also contains antioxidants that help prevent free radicals from damaging your cells, which can lead to serious diseases like cancer.

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